Clinical trials: Anesthesia Time, open to volunteers
Airway Management, Tracheal Intubation
Effect of Night Shift Versus Daytime Duty on Tracheal Intubation Complications and Duration in Surgical Patients
Airway management is one of the most critical steps of anesthesia, and its complications can be life-threatening. Reduced staffing, differences in personnel experience, and physical and mental fatigue during off-hours (evenings…
- Conditions
- Airway Management, Tracheal Intubation, Intubation Complications, General Anesthesia
- Trial name
- NCT07823179
- Testing
- Tracheal Intubation
- Volunteers
- 1,000 people
- Sponsor
- Merve Yazici Kara
Intravenous Anesthesia, Cholelithiasis
Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy
The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy.
- Trial name
- REMIPROP-LOC (NCT07717684)
- Testing
- Remimazolam, Propofol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal de Sergipe
Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures
Synergistic Effect of Intravenous Lidocaine on Anesthetic Induction and Emergence in Patients Undergoing Laparoscopic Cholecystectomy or Gynecological Surgery
This study aims to evaluate the effect of intravenous lidocaine on consciousness changes during anesthesia in patients undergoing laparoscopic cholecystectomy or gynecologic surgery.
- Conditions
- Cholecystectomy, Laparoscopic, Gynecologic Surgical Procedures, Anesthesia and Procedure Related Time Intervals
- Trial name
- Li (NCT07193836)
- Testing
- Normal Saline (0.9% NaCl), Lidocaine, Lidocaine Bolus + Infusion
- Where
- China
- Volunteers
- 195 people
- Sponsor
- General Hospital of Ningxia Medical University
Anesthesia, Anesthesia Complication
Preoperative Blood Volume Optimization Using Transthoracic Echocardiography
Immediately following the induction of general anesthesia, arterial hypotension may occur with an incidence of about 40% in patients classified as ASA 3 or 4.
- Conditions
- Anesthesia, Anesthesia Complication, Anesthesia Induction, Arterial Hypotension
- Trial name
- EchOptimal (NCT06639737)
- Testing
- preoperative stroke volume optimization, Post induction stroke volume optimization
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Caen
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Anesthesia, Local
Split Face Study of the Duration of Local Anesthetics - Fourth Arm
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT06694714
- Testing
- 0.5 ml lidocaine + epinephrine 1:100,000, 1.0 ml lidocaine + epinephrine 1:100,000
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Any Patient Under General Anesthesia With Propofol Induction
A Novel Two-Step Dosing Induction Strategy (The Propofol Challenge Test) to Minimize Propofol Injection Pain
Propofol is the most widely used intravenous hypnotic agent for the induction of general anesthesia owing to its rapid onset and short duration of action.
- Trial name
- PROTECT (NCT07763548)
- Testing
- Bolus injection, Fractionned onjection
- Where
- Belgium
- Volunteers
- 2,000 people
- Sponsor
- Erasme University Hospital
Hysteroscopy, Ambulatory Surgery
Remimazolam-Flumazenil Versus Sevoflurane for Hysteroscopic Day Surgery
This prospective, single-center, randomized controlled trial aims to compare remimazolam anesthesia with planned flumazenil reversal and sevoflurane-based balanced anesthesia in adult women undergoing ambulatory hysteroscopic…
- Conditions
- Hysteroscopy, Ambulatory Surgery, General Anesthesia
- Trial name
- NCT07663877
- Testing
- Remimazolam, Flumazenil, Sevoflurane
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Hypotension on Induction
The Role of Left Ventricular Outflow Tract (LVOT) Velocity-time Integral (VTI) and Respiratory Variability at Peak Rate (Vpeak) in Predicting Hypotension After General Anesthesia Induction
Preoperatively, patients will undergo transthoracic echocardiography measurements approximately 15-30 minutes before induction. TTE will be performed on all patients by an experienced observer; the echocardiography device will be…
- Trial name
- LVOT-VTI-hypot (NCT07121699)
- Testing
- Inotrope
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Anesthesia
Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
The purpose of this study is to assess and compare conditions for tracheal intubation obtained with modified time principal induction with 0.6 mg/kg rocuronium and 1 mg/kg succinylcholine.
- Trial name
- NCT06029049
- Testing
- Modified Time Principle Induction (MTPI) with rocuronium, RSI succinylcholine
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- The University of Texas Health Science Center, Houston
POCD - Postoperative Cognitive Dysfunction, Recovery Time
The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy
In this study, the investigators want to examine the effects of intravenous anesthetic drugs and gases on cognitive functions in the postoperative period in individuals who will undergo surgery for obesity.
- Conditions
- POCD - Postoperative Cognitive Dysfunction, Recovery Time, Postoperative Neurocognitive Disorder, Postoperative Delirium
- Trial name
- NCT07637357
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Comparison of Buffered Versus Non Buffered Local Anesthetic In Inflamed Tissues
"Comparison of Buffered Versus Non-Buffered Local Anesthetic in Patients With Inflamed Tissues for Pain Perception, Onset, Duration and Adverse Effects"
This study aims to determine whether buffered or non-buffered local anesthetic (LA) is more effective and safer for managing pain in patients with inflamed tissues undergoing surgical procedures.
- Trial name
- NCT07592143
- Testing
- Buffered Local Anesthesia
- Volunteers
- 68 people
- Sponsor
- King Edward Medical University
Dexamethasone, Spinal Anesthesia
Dexamethasone and Duration of Spinal Anesthesia
This study will evaluate whether intravenous dexamethasone affects the duration of spinal anesthesia in patients undergoing lower abdominal surgery.
- Conditions
- Dexamethasone, Spinal Anesthesia, Adjuvant
- Trial name
- NCT07819682
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Pakistan
Adenotonsillar Hypertrophy
Teleconsultation vs Face-to-Face Evaluation for Perioperative Respiratory Events in Pediatric Adenotonsillectomy
The goal of this clinical trial is to assess whether preoperative anesthesia teleconsultation is at least equivalent to in-person consultation in preventing perioperative respiratory adverse events (such temporary reduction in…
- Trial name
- Teleped (NCT07175779)
- Testing
- Face-to-Face Preanesthesia Consultation, Telemedicine Preanestehsia Consultation
- Where
- Switzerland
- Volunteers
- 106 people
- Sponsor
- Andrea Saporito
Intrathecal Dexmedetomidine
This Study Aims to Determine Whether Lower Doses (4 µg) of Intrathecal Dexmedetomidine Can Provide Comparable Analgesic Benefits While Minimizing Adverse Hemodynamic Effects in Patients Encountered in Our Setup( Shifa International Hospital Islamabad).
This study aims to determine whether lower doses (4 µg) of intrathecal dexmedetomidine can provide comparable analgesic benefits while minimizing adverse hemodynamic effects in patients encountered in our setup( Shifa…
- Trial name
- NCT07807020
- Testing
- Intrathecal Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Infraclavicular Brachial Plexus Block
Pulse Wave Transit Time After Infraclavicular Block
This prospective observational study aims to evaluate the time-dependent changes in Pulse Wave Transit Time (PWTT) following ultrasound-guided infraclavicular brachial plexus block.
- Trial name
- NCT07669688
- Testing
- Ultrasound-guided infraclavicular brachial plexus block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Total Hip Arthroplasty (THA), Intrathecal Anesthesia
Assessing the Time-Course of Dexmedetomidine-Induced Analgesia Via EEG
Objective: To investigate the temporal dynamics of dexmedetomidine's analgesic effects in the brain using EEG. Methods: Eligible patients scheduled for total hip arthroplasty under intrathecal anesthesia received a continuous…
- Conditions
- Total Hip Arthroplasty (THA), Intrathecal Anesthesia, Hip Osteoarthritis
- Trial name
- NCT06946277
- Testing
- Preemptive Analgesia Of Dexmedetomidine
- Where
- China
- Volunteers
- 20 people
- Sponsor
- China International Neuroscience Institution
Spinal Anesthesia, Prolonged Sensory Block
Impact of Intravenous Dexamethasone on the Duration of Motor and Sensory Block Following Spinal Anesthesia With Chloroprocaine
The purpose of this study is to compare the effect of a single dose of 8 mg of intravenous dexamethasone versus placebo on the duration of sensory and motor block after spinal anesthesia with chloroprocaine.
- Conditions
- Spinal Anesthesia, Prolonged Sensory Block, Prolonged Motor Block
- Trial name
- NCT07837674
- Testing
- Intravenous Dexamethasone, Normal Saline
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Ankle Block, Foot Surgery
Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks
The purpose of this research is to determine if both local anesthetics (mepivacaine and bupivacaine) are similar in their onset of sensory block to assess the efficiency of ultrasound-guided ankle blocks in our practice.
- Trial name
- NCT05425979
- Testing
- Mepivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Knee Arthroscopy
Efficacy of Intravenous Dexamethasone in Prolonging the Duration of Spinal Anesthesia With Chloroprocaine in Knee Arthroscopy
Chloroprocaine is a short-acting local anesthetic that allows rapid recovery and early ambulation but is currently recommended for procedures lasting 40 minutes or less.
- Trial name
- CHLORODEX (NCT07674576)
- Testing
- Sodium Chloride 0.9%, Dexamethasone, Chloroprocaine Injection [Clorotekal]
- Where
- France
- Volunteers
- 60 people
- Sponsor
- CMC Ambroise Paré