Clinical trials: Anesthesia and Analgesia
Morphine Consumption, Postoperative Pain
Ultrasound-Guided Pericapsular Nerve Group Block for Pain Control After Hip Surgery
This study evaluated whether an ultrasound-guided pericapsular nerve group (PENG) block could reduce pain and morphine use during the first 24 hours after hip surgery.
- Trial name
- NCT07906613
- Testing
- Ultrasound-Guided Pericapsular Nerve Group Block with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Cervical Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05717361
- Testing
- ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Surgery, Anesthesia, Local
Block of the Sphenopalatine Nerve Ganglion for Postoperative Analgesia
Transsphenoidal surgery is considered safe and effective and is currently the procedure of choice for the removal of intrasellar lesions.
- Conditions
- Surgery, Anesthesia, Local, Postoperative Pain
- Trial name
- NCT04339231
- Testing
- sphenopalatine ganglion block
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Brachial Plexus Anesthesia, Analgesia
Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia
Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.
- Trial name
- NCT01739270
- Testing
- supraclavicular brachial plexus block
- Where
- Croatia
- Volunteers
- 55 people
- Sponsor
- University Hospital Dubrava
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Virtual Reality, Distraction
Virtual Reality (VR) Could Be a Good Alternative to Relaxing or Pain-relieving Medication
We want to investigate whether Virtual Reality (VR) could be a good alternative to the relaxing or pain-relieving medications that are often used to alleviate anxiety when patients undergo surgery under local anesthesia.
- Conditions
- Virtual Reality, Distraction, Elderly (people Aged 65 or More)
- Trial name
- NCT06649383
- Testing
- Virtual reality
- Where
- 2 sites in Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pether Jildenstal
Pain
Pupillometry - Future of Objective Pain Reaction Measurement While Unconscious
This study aims to assess the usefulness of pupillometry as a nociceptive indicator during elective orotracheal intubation in patients given intravenous lignocaine pre-intubation as compared to a placebo pre-intubation.
- Trial name
- NCT04000126
- Testing
- Pupil reflex dilation measurement (PRD), PPI (Pupillary Pain Index), lidocaine
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury
Cutaneous Sensory Blockade
Effects of Injection Volume and Site on Sensory Distribution After Rectus Sheath Block
This randomized controlled study aims to evaluate the effects of local anesthetic injection volume and injection site on cutaneous sensory distribution following ultrasound-guided rectus sheath block (RSB).
- Trial name
- RSB-SENSE (NCT07876297)
- Testing
- Ultrasound-Guided Upper Rectus Sheath Block (20 mL), Ultrasound-Guided Upper Rectus Sheath Block (30 mL), Ultrasound-Guided Middle Rectus Sheath Block (20 mL)
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Chiang Mai University
Modified Radical Mastectomy, Post Operative Pain, Acute
Comparıson of Analgesıc Effıcacy of Dıfferent Volumes of Serratus Posterior Superıor Intercostal Plane Block After Modıfıed Radıcal Mastectomy Surgery
The aim of researchers is to compare the effects of three different local anesthetic concentrations and volumes on opioid consumption, postoperative analgesic efficacy, and pain scores during ultrasound-guided SPSIP blocks in…
- Conditions
- Modified Radical Mastectomy, Post Operative Pain, Acute, Facial Plane Blocks
- Trial name
- NCT07670078
- Testing
- Serratus Posterior Superior Intercostal Plane (SPSIP) block 40 ml of 0.1875% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 50 ml of 0.15% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 30 ml of 0.25% bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
Pain Management
Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids.
- Trial name
- NCT03757715
- Testing
- Bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Postoperative Pain, Opioid Use
Continuous Serratus Anterior Blockade for Sternotomy
This is a pilot study to assess the feasibility of a full study. The purpose is to assess the analgesic effectiveness of the serratus anterior plane (SAP) block following cardiac surgery.
- Conditions
- Postoperative Pain, Opioid Use, Quality of Life
- Trial name
- Cardiac-SAP (NCT04648774)
- Testing
- Serratus anterior plane (SAP) block
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Post-operative Pain, Total Shoulder Arthroplasty
LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
This will be a single-center, prospective, randomized controlled cross-sectional study comparing interscalene brachial plexus block with liposomal bupivacaine versus bupivacaine with epinephrine and PF dexamethasone in patients…
- Conditions
- Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
- Trial name
- NCT03887650
- Testing
- Liposomal Bupivicaine 1.3%, Bupivacaine 0.5%
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Hartford Hospital
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Hip Fracture
A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for…
- Trial name
- NCT01547468
- Testing
- Femoral Nerve Catheterization, Intravenous Opioids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leslie Thomas
Post Operative Pain, Cesarean Section Complications
Postoperative Analgesic Efficacy of Trans Abdominis Plane Block
Transverse abdominis plane (TAP) block is an effective method to manage postoperative pain in patients with midline abdominal wall incisions.
- Trial name
- NCT05831501
- Testing
- Trans abdominis plane block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Armed Forces Hospital, Pakistan
Infertility, Pain
MEOPA Breathing Analgesia for Oocyte Retrieval(KALOVAL)
The purpose of this study is to assess pain, at or after oocyte retrieval, the effectiveness of self-controlled inhalation analgesia by nitrous oxide (N2O of 50% and 50% O2) by the patient compared to a local anesthesia combined…
- Trial name
- KALOVAL (NCT00853177)
- Testing
- MEOPA inhalation, xylocaine
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Anesthesia, Cesarean Section Pain
Effect of Single-Dose Dexamethasone on Postoperative Pain After Cesarean Section Under Spinal Anesthesia
This study looked at whether giving a single dose of dexamethasone (a steroid medicine, 8 mg given into the vein) before a cesarean section could reduce pain after the operation.
- Conditions
- Spinal Anesthesia, Cesarean Section Pain, Postoperative Pain
- Trial name
- NCT07718360
- Testing
- Dexamethasone (IV), Normal Saline 0.9% Infusion Solution
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- KRL Hospital, Islamabad
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia and to evaluate the impact of COVID-19 pandemic on obstetric anesthesia and analgesia in Czech Republic and…
- Trial name
- OBAAMA-COV (NCT04912791)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 5,000 people
- Sponsor
- Brno University Hospital
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
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