Clinical trials: Anesthesia and Analgesia
Pain, Postoperative
Exparel vs. Standard Bupivicaine for Abdominoplasty
Background \& study question: Strategies for post-operative pain control that make use of various different types of medicines are advantageous both for patient comfort and for minimizing the use of opioid pain medicines and…
- Trial name
- NCT01853176
- Testing
- Liposomal Injection Bupivacaine (Exparel), Standard bupivicaine
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Emory University
Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Continuous Interscalene Blocks and Rebound Pain
The primary objectives of this present study are to examine whether a continuous interscalene block of a total duration of 48 hours reduces the incidence of rebound pain comparatively to single-shot interscalene block, through…
- Conditions
- Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Interscalene Analgesia, Interscalene Blocks
- Trial name
- NCT07770165
- Testing
- Continuous interscalene nerve block, Interscalene Block
- Where
- Canada
- Volunteers
- 154 people
- Sponsor
- University of Calgary
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Postoperative Pain, Cholecystectomy, Laparoscopic
M-TAPA vs ESPB for Postoperative Analgesia After Laparoscopic Cholecystectomy
Postoperative pain after laparoscopic cholecystectomy can negatively affect patient comfort, recovery, and opioid consumption. Regional abdominal wall blocks are commonly used as part of multimodal analgesia to improve…
- Trial name
- NCT07403682
- Testing
- Modifiye throcoabdominal nerve block through the perichondrial approach (M-TAPA), erector spinae plane block (ESPB)
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Cancer of Pancreas
Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery
The purpose of this randomized controlled trial is to investigate the effects of epidural anesthesia and analgesia on the overall survival，disease-free survival and recovery in patients undergoing pancreatic cancer surgery.
- Trial name
- NCT03245346
- Testing
- GEA, PCEA, GA
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Fudan University
Bimalleolar Fractures of the Ankle., Sciatic Nerve Block.
To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade
Clonidine as an adjuvant to local anaesthetics prolongs the postoperative analgesia. It is predominantly an alpha 2 agonist, but does have some alpha 1 activity. Clonidine alone produces analgesia.
- Conditions
- Bimalleolar Fractures of the Ankle., Sciatic Nerve Block., Saphenous Nerve Block., Post Operative Analgesia Duration.
- Trial name
- NCT01759524
- Testing
- Bupivacaine, Lidocaine
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Adverse Anesthesia Outcome
Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific Inhibitor
Acute pain is the result of activating nociceptive pathways in both the peripheral and central nervous system. The origin of most acute pain from surgical stimulation is the mechanical trauma of the local tissue and the…
- Trial name
- NCT02884986
- Testing
- Etoricoxib
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Labor Pain, Epidural Analgesia for Labour and Delivery
Early Labor Pre-Marking for Epidural Analgesia: Ultrasound vs Manual Palpation
The goal of this clinical trial is to learn if finding and marking the best spot on the back early in labor helps doctors perform epidural pain relief more successfully in pregnant women.
- Conditions
- Labor Pain, Epidural Analgesia for Labour and Delivery, Neuraxial Ultrasound
- Trial name
- NCT07669441
- Testing
- Preprocedural Spinal Ultrasound, Conventional Landmark Palpation
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Postoperative Pain, Total Knee Arthroplasty
Continuous Femoral Nerve Block Versus Local-wound Infiltration Analgesia For Patients Receiving Total Knee Arthroplasty --- A Randomized Controlled Trial
Post-operative pain after total knee arthroplasty is usually severe and impair the functional recovery of operated joints.The purpose of this study is to determine whether post-operative continuous femoral nerve block analgesia…
- Trial name
- NCT02284620
- Testing
- CFNB group, LWI group
- Where
- China
- Volunteers
- 320 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Back Pain, Lumbar
Massage and Electroacupuncture in Chronic Lumbar Pain
The aim of this study is to evaluate and compare in patients with chronic back pain two therapeutic interventions: a) the combination of massage and electroacupuncture; and b) the application of epidural analgesia in pain…
- Conditions
- Back Pain, Lumbar, Anesthesia, Local, Epidural
- Trial name
- NCT04108546
- Testing
- Electroacupuncture device, Epidural analgesia
- Where
- 2 sites in Greece
- Volunteers
- 110 people
- Sponsor
- University of Thessaly
Surgical Injury, Stress, Physiological
Effect of a Bundle of Non-pharmacological Interventions on the Stress Response to Surgery
Rationale: Surgical trauma and post-surgical pain induce a physiological stress response that can be detrimental to the patient.
- Conditions
- Surgical Injury, Stress, Physiological, Stress, Psychological, Pain, Postoperative
- Trial name
- SPACU-lab (NCT05638152)
- Testing
- implementation of a bundle of non-pharmacological interventions aimed at stress reduction
- Volunteers
- 90 people
- Sponsor
- The Netherlands Cancer Institute
Hip Fracture, Analgesia
Ultrasound Percapsular Nerve Group Block VS Fascia Iliaca Block for Hip Fracture
Spinal anesthesia (SA) is a widely accepted anesthetic technique for hip fracture repair among elderly. Positioning for SA can be extremely painful. Effective management of pain is important for these patients comfort.
- Conditions
- Hip Fracture, Analgesia, Acute Pain
- Trial name
- NCT04285333
- Testing
- fascia iliaca block, percapsular nerve group block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Postoperative Pain
Analgesia Nociception Index in Orthognathic Surgery
This study aims to determine whether goal-directed analgesia using ANI(Analgesia/Nociception Index) can improve the quality of postoperative recovery in patients undergoing maxillofacial surgery.
- Trial name
- NCT06205355
- Testing
- Analgesia/Nociception Index (ANI) monitoring, Standard monitoring
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Block
Evaluating the Effectiveness of Bilateral ESPB in Addition to Standard Analgesia at Reducing Opioid Consumption
Study the benefits of a Erector Spinae nerve block for pain control and decrease narcotics usage after mammoplasty in an ambulatory setting
- Trial name
- NCT03954249
- Testing
- Erecto Spinae nerve block, Multimodal Analgesia
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Proximal Femur Fracture, Hip Fracture
Ultrasound-Guided PENG Block vs Femoral Nerve Block for Analgesia Before Spinal Anesthesia in Hip Fracture Surgery
This study will compare two types of ultrasound-guided nerve blocks-Pericapsular Nerve Group (PENG) block and Femoral Nerve Block (FNB)-to evaluate their effectiveness in reducing pain before spinal anesthesia in patients who…
- Conditions
- Proximal Femur Fracture, Hip Fracture, Pain Management, Spinal Anesthesia
- Trial name
- NCT06989047
- Testing
- Pericapsular Nerve Group (PENG) Block, Femoral Nerve Block (FNB)
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Renal Insufficiency, Chronic, Acute Pain
Efficacy Transverse Abdominal Plane (TAP) Block Renal Transplant Surgery
The objective of this study is to evaluate the efficacy and safety of transverse abdominal plane block in patients undergoing renal transplant surgery.Adult renal transplant recipients will be prospectively randomized to receive…
- Conditions
- Renal Insufficiency, Chronic, Acute Pain, Kidney Transplantation, Anesthesia, Conduction
- Trial name
- NCT03181438
- Testing
- TAP Block, Saline Group
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Federal University of São Paulo
Total Knee Arthroplasty, Postoperative Pain
Continuous Adductor Canal Block (CACB) Combined With İnfiltration Between the Popliteal Artery and Capsule of the Knee (iPACK) Block vs Continuous Adductor Canal Block Alone After Total Knee Arthroplasty
This study compares the effects of adding an infiltration between the popliteal artery and capsule of the knee (iPACK) block to a continuous adductor canal block (CACB) versus continuous adductor canal block alone on…
- Trial name
- NCT07851506
- Testing
- IPACK block, Continuous adductor canal block (CACB)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Pain, Tonsillectomy
Ketamine Gargle for Pain After Pediatric Tonsillectomy
Post-tonsillectomy pain in children is a common and clinically significant problem that may lead to poor oral intake, dehydration, and delayed recovery.
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- KET-TONSIL (NCT07558044)
- Testing
- Ketamine Hydrochloride in saline, Normal Saline (0.9% NaCl)
- Where
- Venezuela
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Pain, Postoperative, Cesarean Section
Bilateral Ultrasound-Guided Transversus Abdominis Plane (Tap) Block and Erector Spinal Plane (Esp) Block
Transversus Abdominis Plane Block (TAPB) is frequently used for the management of postoperative pain in patients undergoing cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section, Erector Spinae Plane Block, Transversus Abdominis Plane Block
- Trial name
- NCT05625009
- Testing
- Procedure/Surgery: Transversus Abdominis Plane Block (TAPB), Procedure/Surgery: Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Pain Syndrome, Analgesia
Erector Spinae Plane Block Versus Paravertebral Block for Analgesia After Cardiac Surgery (PEPS)
The purpose of this randomized double-blind study is to compare the analgesic efficacy of the bilateral Erector Spinae Plane (ESP) block versus the bilateral Thoracic Paravertebral block (TPVB), by ultrasound-guided single…
- Conditions
- Pain Syndrome, Analgesia, Anesthesia, Local
- Trial name
- PEPS (NCT04546113)
- Testing
- Ultrasound-guided Bilateral Paravertebral Block performed with a 20 ml injection of Ropivacaine 3,75 mg/ml/side, Ultrasound-guided Bilateral Erector Spinae plane Block performed with a 20 ml injection ropivacaine 3,75 mg/ml/side
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Institut Mutualiste Montsouris
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.