Clinical trials: Anesthesia and Analgesia
Appendectomy, Laparoscopic, Pediatric Anesthesia
Rectus Sheath Block and Local Wound Infiltration in Pediatric Laparoscopic Appendectomies
Laparoscopic appendectomy surgeries are among the most commonly performed procedures in childhood. However, they are associated with moderate to severe postoperative pain.
- Conditions
- Appendectomy, Laparoscopic, Pediatric Anesthesia, Nerve Block/Methods, Regional Anesthesia
- Trial name
- NCT06913205
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Bursa City Hospital
Surgery With General Anesthesia, Gynecologic Surgical Procedures
COMPARISON OF PLAIN BLOCKS FOR POSTOPERATIVE PAIN MANAGEMENT IN GYNECOLOGICAL ABDOMINAL SURGERIES
This study compares the effects of transversus abdominis plane (TAP) block, quadratus lumborum block (QLB), and erector spinae plane block (ESP) on postoperative morphine consumption, pain scores, patient satisfaction, and side…
- Conditions
- Surgery With General Anesthesia, Gynecologic Surgical Procedures, Plane Block, Postoperative Pain Management
- Trial name
- ESP QLB TAP (NCT07021105)
- Testing
- ESP Plane block, QLB plane block, TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Intertransverse Process Block, Subcostal Transverse Abdominis Plane Block
Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block After Laparoscopic Sleeve Gastrectomy
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal Transversus Abdominis Plane Block (TAPB) in patients undergoing laparoscopic sleeve…
- Conditions
- Intertransverse Process Block, Subcostal Transverse Abdominis Plane Block, Sleeve Gastrectomy, Postoperative Pain
- Trial name
- NCT07591129
- Testing
- Intertransverse Process Block, The Subcostal Transversus Abdominis Plane Block (TAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery
ESPB vs SPSIP for Postoperative Analgesia After CABG
This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral…
- Conditions
- Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery, Postoperative Pain Management
- Trial name
- ESP-SPSIP-CABG (NCT07388745)
- Testing
- Ultrasound-guided Erector Spinae Plane Block (ESPB), Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kutahya Health Sciences University
Cardiac Implantable Electronic Device, Nerve Block
PECs for Implantable Cardiac Electronic Device Insertion
The aim of this study is to evaluate the feasibility of the Pectoralis Nerve (PECS) block for CIED insertion.
- Conditions
- Cardiac Implantable Electronic Device, Nerve Block, Anesthesia, Analgesia
- Trial name
- NCT05528627
- Testing
- Pectoral Nerve (PECs) block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Antalya Training and Research Hospital
Pectus Excavatum, Chest Deformities
SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum
This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum.
- Trial name
- NCT07697222
- Testing
- Postoperative Analgesia Protocol, Bispectral Index Monitoring, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Pain, Postoperative, Pain Prediction
Venous Cannulation Pain to Guide Choice of Anesthetic Method
The investigators have recently shown that pain associated with peripheral venous cannulation can be used to predict the risk of postoperative pain, where patients grading their pain associated with venous cannulation (VCP) above…
- Conditions
- Pain, Postoperative, Pain Prediction, Laparoscopic Surgery, Venous Cannulation Pain
- Trial name
- NCT04751812
- Testing
- High-pain multimodal anesthesia with opioids, Low-pain opioid free, Standard of care
- Where
- Sweden
- Volunteers
- 270 people
- Sponsor
- Region Halland
Postoperative Pain, Obesity
Comparison of Two Magnesium Sulfate Protocols in Opioid-Free Anesthesia for Bariatric Surgery
This retrospective observational study aims to compare postoperative morphine consumption in patients undergoing bariatric surgery with opioid-free anesthesia (OFA) using two different intravenous magnesium sulfate administration…
- Conditions
- Postoperative Pain, Obesity, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA-MG (NCT07077031)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital HM Nou Delfos
Surgery, Anesthesia, Local
Block of the Sphenopalatine Nerve Ganglion for Postoperative Analgesia
Transsphenoidal surgery is considered safe and effective and is currently the procedure of choice for the removal of intrasellar lesions.
- Conditions
- Surgery, Anesthesia, Local, Postoperative Pain
- Trial name
- NCT04339231
- Testing
- sphenopalatine ganglion block
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Anesthesia
The Effect of Combined Bilateral Infraorbital and Infratrochlear Nerve Block in Nasal Surgeries
The aim of the study is to assess the efficacy of adding a pre-emptive combined bilateral infraorbital and infratrochlear nerve blocks with bupivacaine 0.25% in decreasing intraoperative and postoperative analgesics consumption…
- Trial name
- NCT06174675
- Testing
- combined bilateral infraorbital and infratrochlear nerve blocks
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Tonsillitis
Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy
Tonsillectomies are among the most common surgical procedures performed in pediatric populations, with more than 14,000 procedures performed annually in Ontario, with more than 80% being performed to treat sleep-disordered…
- Trial name
- NCT07176533
- Testing
- Suprazygomatic maxillary nerve block (SZMN) with bupivacaine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cataract, Analgesia
Analgetic Effect of Two Solutions of Intracameral Anesthesia During Cataract Surgery in Patients
Purpose: The aim of the study was to compare the analgetic effect of two solutions of intracameral anesthesia in patients undergoing cataract surgery and assess the factors influencing the patients' postoperative activities.
- Conditions
- Cataract, Analgesia, Ophthalmological Disorder
- Trial name
- NCT04166578
- Testing
- lignocaine, Phacoemulsyfication, Intraocular lens implantation
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Medical University of Lublin
Pain
Lidocaine-Prilocaine Cream in Conjunction With Paracervical Block for Pain With Abortion
The investigators theorize that the application of a lidocaine-prilocaine cream 5-10 minutes prior to the administration of a paracervical block could decrease pain associated with its administration and pain with abortion…
- Trial name
- NCT03508804
- Testing
- Lidocaine-Prilocaine Cream, 1% Lidocaine Paracervical Block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Obstetric Pain, Labor Pain
Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia
The purpose of this prospective randomized controlled study is to compare the number of physician top-up interventions during the first stage of labour between two different neuraxial analgesia techniques : the dural puncture…
- Conditions
- Obstetric Pain, Labor Pain, Anesthesia
- Trial name
- DPE (NCT04728048)
- Testing
- Dural puncture epidural, Standard epidural
- Where
- Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Other Acute Postoperative Pain, Pain, Postoperative
Effects of Local Anaesthetic Infusion Rates on Nerve Block Duration
This trial is a part of the project: 'A novel technique for reliable, precise and safe postoperative pain management' (project no. 65-2014-3).
- Conditions
- Other Acute Postoperative Pain, Pain, Postoperative, Anaesthesia
- Trial name
- NCT02801799
- Testing
- Varying infusion rates of Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Effects of Anesthesia Spinal and Epidural in Pregnancy
Air Versus Saline Solution for the Localization of the Epidural Space in Labour Analgesia
Epidural space localization using loss of resistance technique with air (ALOR) is controversial in obstetric analgesia due to a minor efficacy and risk of complications, compared with loss of resistance technique with saline…
- Trial name
- NCT02792933
- Testing
- air in epidural space, saline in epidural space
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Femoral Nerve Disease
Femoral Nerve Block: Anatomical Insertion Point - A Prospective Randomised Double-Blind Controlled Trial
Nerve blocks are an effective way to control pain after surgery. There are two major nerves that provide sensation to the knee: the femoral nerve provides sensation to the front of the knee and sciatic nerve provides sensation to…
- Trial name
- FNB (NCT00732706)
- Testing
- Sartorius Muscle Twitch, Quadriceps Muscle Twitch
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Shoulder Arthroscopy, Postoperative Pain
Magnesium Sulfate With Standard Combined Costoclavicular-Suprascapular Block for Pain Relief After Shoulder Arthroscopy.
This study aims to evaluate whether adding magnesium sulfate to a combined costoclavicular and suprascapular nerve block improves postoperative pain control in patients undergoing shoulder arthroscopy.
- Conditions
- Shoulder Arthroscopy, Postoperative Pain, Regional Anesthesia
- Trial name
- CCSS-Mg (NCT07798115)
- Testing
- Bupivacaine, Magnesium sulfate (MgSO4), Normal Saline (NS)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
Anesthesia, Analgesia
Intrathecal Morphine vs. Quadratus Lumborum Block for Pain in Laparoscopic Nephrectomy
In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and İntrathecal morphine (ITM) on postoperative acute pain scores and opioid consumption in the first 24 hours after…
- Conditions
- Anesthesia, Analgesia, Acute Pain, Patient Controlled Analgesia
- Trial name
- NCT06630858
- Testing
- Subcostal Anterior Quadratus Lumborum Block, Intrathecal Morphine, Patient Controlled Analgesia (IV PCA)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain, Cesarean Section Pain
Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section
This study aims to compare three different doses of dexmedetomidine, when combined with a fixed dose of ketamine, for pain control in women undergoing cesarean section.
- Trial name
- KETODEX-CS (NCT07022821)
- Testing
- Dexmedetomidine, ketamine
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Memorial Hospital
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