Clinical trials: Anesthesia and Analgesia
Anesthesia
Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Analgesia, Side Effects and Patient 's Satisfaction
Intrathecal morphine and fentanyl are used for anesthesia and perioperative pain management in caesarian section. Despite the fact that spinal Fentanyl is better tolerated, might not be enough for postoperative pain control.
- Trial name
- FvMinSA (NCT05533229)
- Testing
- Fentanyl, Morphine
- Where
- Romania
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr. Mihai Octavian Botea
Postoperative Pain
Effect of Different Volumes of SPSIP Block in Breast Surgery
This randomized, double-blind study will compare the effectiveness of three different volumes of serratus posterior superior intercostal plane block for postoperative pain control in patients undergoing unilateral breast surgery…
- Trial name
- SPSIP-VOLUME (NCT07783386)
- Testing
- Bupivacaine 0.25% (20 mL), Bupivacaine 0.25% (30 mL), Bupivacaine 0.25% (40 mL)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Anesthesia, Analgesia
Subcostal Approach to Anterior Quadratus Block Versus Thoracic Paravertebral Block for Laparoscopic Nephrectomy
In this study, it was aimed to evaluate the effects of subcostal anterior quadratus lumborum block (S-QLB3) and thoracic paravertebral block (TPVB) on postoperative acute pain scores and opioid consumption in the first 24 hours…
- Conditions
- Anesthesia, Analgesia, Acute Pain, Patient Controlled Analgesia
- Trial name
- NCT05191966
- Testing
- Subcostal Anterior Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Anterior Cruciate Ligament Reconstruction, Regional Anesthesia, Saphenous Nerve Block
Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction
For patients undergoing Anterior Cruciate Ligament reconstruction surgery, the postoperative period can be a painful experience without adequate pain management.
- Trial name
- NCT01586806
- Testing
- Bupivacaine Only, Bupivacaine with 1 mg of Dexamethasone, Bupivacaine with 4 mg of Dexamethasone
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Hospital for Special Surgery, New York
Thoracic Diseases, Thoracic Surgery
Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery
Thoracic surgery, and surgery involving the chest wall in general, is associated with poorly controlled acute pain, which may result in delayed functional recovery, and may progress to chronic pain.
- Conditions
- Thoracic Diseases, Thoracic Surgery, Rib Fractures, Pain, Postoperative
- Trial name
- SAPB (NCT03768193)
- Testing
- Deep serratus anterior plane block, Surgically-placed paravertebral block
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mater Misericordiae University Hospital
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative, Surgical Wound
Transversus Thoracis Muscle Plane Block for Sternotomy Pain in Cardiac Surgery
Sternotomy pain is usually significant after cardiac surgery. Analgesic options for sternotomy in cardiac surgery are often limited. Poorly controlled acute pain is an important factor to development of chronic postsurgical pain.
- Conditions
- Pain, Postoperative, Surgical Wound, Cardiac Event
- Trial name
- NCT04596163
- Testing
- Transversus thoracis muscle plane block
- Where
- Hong Kong
- Volunteers
- 86 people
- Sponsor
- Chinese University of Hong Kong
Intertransverse Process Block, External Oblique Intercostal Plane Block
Intertransverse Process Block Versus External Oblique Intercostal Plane Block After Laparoscopic Sleeve Gastrectomy
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal External Oblique Intercostal Plane Block (EOIPB) in patients undergoing laparoscopic…
- Conditions
- Intertransverse Process Block, External Oblique Intercostal Plane Block, Sleeve Gastrectomy, Regional Anaesthesia
- Trial name
- NCT07591116
- Testing
- Intertransverse Process Block, External Oblique Intercostal Plane Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Thoracic Anesthesia, Thoracotomy
Opioid Consumption After Thoracotomy and Factors Affecting Postoperative Acute Pain
Thoracic surgery operations constitute a significant portion of surgical procedures performed in hospitals. In the United States, more than 50,000 thoracic surgical procedures are performed annually, and more than 80% of these…
- Conditions
- Thoracic Anesthesia, Thoracotomy, Opioid, Postoperative Pain Management
- Trial name
- NCT07329855
- Testing
- Opioid Analgesic, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Postoperative Pain, Shoulder Surgeries Operations
Interscalene Versus Costoclavicular Blocks for Shoulder Surgery
AIM: Shoulder surgeries are among the most painful surgical procedures in orthopedic practice. Interscalene brachial plexus block, although the most commonly utilized regional anesthesia technique for alleviating pain following…
- Conditions
- Postoperative Pain, Shoulder Surgeries Operations, Regional Anesthesia, Costoclavicular Block
- Trial name
- NCT06953947
- Testing
- Costoclavicular block, Interscalene block, Interscalene Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Sakarya University
Ultrasound-guided Regional Anesthesia, Shoulder Surgery
Distant Extrafascial Injection vs Subfascial Injection for Interscalene Block: Acute Pain Outcomes and Rates of Complications
The objective of this randomized controlled trial is to compare the analgesic efficacy and the safety profile between two techniques of injection for the interscalene block.
- Conditions
- Ultrasound-guided Regional Anesthesia, Shoulder Surgery, Interscalene Block, Postoperative Analgesia
- Trial name
- NCT02074397
- Testing
- Distant extrafascial injection, Subfascial injection
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Pain
Clonidine and Morphine in Caudal Anesthesia
Hypothesis: The combined use of Clonidine and Morphine in caudal anesthesia provides better postoperative analgesia than either drug alone after urogenital pediatric surgery.
- Trial name
- NCT00672347
- Testing
- Clonidine, Morphine, Bupivacaine plus clonidine and morphine
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Minas Gerais
Spinal Anesthesia, Cesarean Section Pain
Effect of Single-Dose Dexamethasone on Postoperative Pain After Cesarean Section Under Spinal Anesthesia
This study looked at whether giving a single dose of dexamethasone (a steroid medicine, 8 mg given into the vein) before a cesarean section could reduce pain after the operation.
- Conditions
- Spinal Anesthesia, Cesarean Section Pain, Postoperative Pain
- Trial name
- NCT07718360
- Testing
- Dexamethasone (IV), Normal Saline 0.9% Infusion Solution
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- KRL Hospital, Islamabad
Shoulder Pain, Injury of Shoulder Region
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure.
- Conditions
- Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff
- Trial name
- NCT01538459
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lifespan
Hip Fractures, Anesthesia Local
Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block
The main objective of the trial is to complete a double-blinded randomized controlled trial with crossover design of a lumbosacral plexus block with the Suprasacral Parallel Shift technique guided by ultrasound/magnetic resonance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Perioperative
- Trial name
- NCT02593370
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Thomas F. Bendtsen
Epidural; Anesthesia
Does Ultrasound Increase the First-pass Success of Epidural Space Identification in Obese Parturients
Obesity is associated with difficulties in epidural space catheterization. The investigators want to prove that a pre-procedural ultrasound exam of lumbar spine increase the first-pass success rate of the epidural space…
- Trial name
- NCT04352283
- Testing
- Preprocedural ultrasound exam of lumbar spine
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Caen
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Postoperative Pain, Acute
Anterior Suprascapular Versus Interscalene Block for Postoperative Analgesia After Arthroscopic Shoulder Surgery in the Outpatient Setting
Shoulder surgery performed in the outpatient setting can be associated with moderate to severe postoperative pain, especially during the first hours after surgery.
- Trial name
- NCT07831096
- Testing
- Interscalene Nerve Block, Anterior suprascapular nerve block, Ropivacaine
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Sette Laghi
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - International
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic and Slovak Republic.
- Trial name
- OBAAMA-INT (NCT02380586)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 3,040 people
- Sponsor
- Brno University Hospital
Anesthesia, Regional Anesthesia
Laparoscopic Sleeve Gastrectomy Surgery and External Oblique Intercostal Block
In obese patients, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay.
- Conditions
- Anesthesia, Regional Anesthesia, Morbid Obesity, Postoperative Pain
- Trial name
- NCT05822479
- Testing
- Bilateral ultrasound guided external oblique intercostal block (EOIB), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
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