Clinical trials: Anesthesia and Analgesia
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Cervical Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05717361
- Testing
- ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Post Operative Recovery, Post Operative Nausea and Vomiting (PONV)
A COMPARATIVE STUDY BETWEEN OPIOID-FREE GENERAL ANAESTHESIA AND OPIOID-BASED GENERAL ANAESTHESIA ON THE QUALITY OF RECOVERY IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC HYSTRECTOMY: A Randomized Trial
the intent of this study To compare the efficacy of opioid free general anaesthesia versus opioid based general anaesthesia to achieve enhanced recovery regarding post-operative pain and post-operative nausea and vomiting…
- Conditions
- Post Operative Recovery, Post Operative Nausea and Vomiting (PONV), Post Operative Analgesia
- Trial name
- NCT07739641
- Testing
- Fentanyl-Based Anesthesia, Opioid-Free Anaesthesia (Dexmedetomidine, Ketamine, and Lidocaine)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Analgesia, Pain, Postoperative
Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block
Objective: The authors hypothesized that combined deep and superficial serratus anterior plane block (SAPB) is as effective as erector spinae plane block (ESPB) for intraoperative and postoperative analgesia for video-assisted…
- Conditions
- Analgesia, Pain, Postoperative, Thoracic, Anesthesia
- Trial name
- NCT06073197
- Testing
- erector spinae plane block, combined deep and superficial serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uludag University
Knee Surgeries, Total Ankle Arthroplasty
Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee Surgery
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee…
- Conditions
- Knee Surgeries, Total Ankle Arthroplasty, Anterior Cruciate Ligament (ACL) Tear, Posterior Cruciate Ligament Tear
- Trial name
- NCT07700797
- Testing
- Adductor canal block with IPACK, 4 in 1 block
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain, Upper Extremity Fracture
Ropivacaine Alone Versus Ropivacaine Plus Lidocaine With or Without Epinephrine for Supraclavicular Brachial Plexus Block in Upper Limb Orthopedic Surgery
This randomized controlled trial compared three local anesthetic solutions for ultrasound-guided supraclavicular brachial plexus block in adults aged 18 to 59 years undergoing upper limb orthopedic and trauma surgery at a general…
- Conditions
- Postoperative Pain, Upper Extremity Fracture, Anesthesia, Conduction
- Trial name
- NCT07907666
- Testing
- ropivacaine, lidocaine, lidocaine with epinephrine
- Where
- Mexico
- Volunteers
- 138 people
- Sponsor
- Instituto Mexicano del Seguro Social
Analgesia, Pain
Effectiveness of Ultrasound (US) Guided Supraclavicular Block
This research study is being done in order to find out if there is any difference in the effectiveness of ultrasound guided supraclavicular brachial plexus nerve block that can be achieved with 3 different amounts of ropivacaine…
- Trial name
- NCT00923494
- Testing
- 20 ml of ropivacaine 0.5%, 30 ml of ropivacaine 0.5%, 40 ml of ropivacaine 0.5%
- Where
- United States
- Sponsor
- Baylor College of Medicine
Post Operative Pain
Postoperative Analgesia in Patients Undergoing Elective Lumbar Fusion Operations Under General Anesthesia
It was proven that intrathecal opioids are considered as an effective means of pain control in several major surgical interventions including spine surgeries.
- Trial name
- NCT05338320
- Testing
- Ultrasound Guided Erector Spinae Plane Block, Intrathecal morphine, General anesthesia using intravenous fentanyl (1µg/kg)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Coxarthrosis, Pain, Postoperative
Lumbar ESPB in Hip Replacement Surgery
In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery.
- Conditions
- Coxarthrosis, Pain, Postoperative, Pain, Acute, Pain, Chronic
- Trial name
- ESPB_HIP (NCT06282666)
- Testing
- Spinal anesthesia, lumbar erector spinae plane block, Epidural analgesia
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Anesthesia , Analgesia, Breast Surgery
Intraoperative Music and Propofol Consumption in Breast Surgery
The goal of this study is to find out whether listening to music during surgery can reduce the amount of propofol, an anesthesia medicine, needed in patients having elective breast surgery.
- Trial name
- NCT07687095
- Testing
- Intraoperative Music
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Uludag University
Breast Cancer
Continuous Serrates Plane Block in Axillary Dissection
Patients undergone to axillary dissection during breast surgery with a PECS I, II block will be randomized to receive either a serratus plane continuous local anesthetic infusion through a multiple hole catheter or nothing.
- Trial name
- NCT03992859
- Testing
- Continuous serratus plane block
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Head and Neck Cancer, Anesthesia
Effects of Minimal-Flow Sevoflurane and Multimodal Analgesia in Head and Neck Cancer Surgery
This study evaluates the anesthetic-sparing and renal protection effects of minimal-flow sevoflurane anesthesia combined with multimodal analgesia using dexmedetomidine, ketamine, and lidocaine in head and neck cancer patients…
- Conditions
- Head and Neck Cancer, Anesthesia, Renal Protection, Acute Kidney Injury
- Trial name
- NCT06521697
- Testing
- Multimodal analgesia using dexmedetomidine-ketamine-lidocaine mixture, Minimal flow sevoflurane
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Postoperative Pain, Percutaneous Nephrolithotomy
The Effectiveness of Quadro İliac Plane Block in Percutaneous Nephrolithotomies
Our aim was to investigate the effect of quadro iliac plane block on postoperative analgesia in patients undergoing percutaneous nephrolithotomy surgery and to determine which areas of the skin this block anesthetizes.
- Trial name
- NCT07203859
- Testing
- Quadro-İliac Plane Block(QİPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Analgesia
Erector Spinae Plane Block Versus General Anesthesia in Breast Cancer Surgeries
This study aims at comparing the analgesic efficacy and safety of bilevel erector spinae versus single level versus general anesthesia for breast cancer surgeries
- Trial name
- NCT05429489
- Testing
- Bilevel erector spinae plane block, Single level erector spinae plane block, Intravenous morphine
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- National Cancer Institute, Egypt
Pain, Analgesia
Thermomechanical Distraction and Social Anesthesia in Interventional Radiology to Improve Patient Satisfaction
The study will prospectively analyze the analgesic and anxiolytic effects of thermomechanical stimulation (cold and vibration effects) with or without patient selected music preference during non-sedating interventional radiology…
- Conditions
- Pain, Analgesia, Anxiety
- Trial name
- NCT04236674
- Testing
- Buzzy thermomechanical device, Music Selection
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Temple University
Acute Pain, Regional Anesthesia
Regional Analgesia in Combination With Cryoanalgesia to Prevent Acute Pain Following Nuss Procedure
Funnel chest deformation is a painful procedure, which requires high doses and long time used of opioids. It makes difficult introduction of ERAS protocol.
- Trial name
- NCT05589246
- Testing
- regional analgesia with cryolesia
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Pomeranian Medical University Szczecin
Mastectomy, Rhomboid Intercostal Block
Effects of Rhomboid Intercostal Block on Postoperative Pain Management and Chronic Pain Incidence in Mastectomies
The goal of this clinical trial is to evaluate the effects of the Rhomboid Intercostal Block (RIB) on postoperative chronic pain prevalence at 3 months (primary outcome) and on acute pain control, total opioid consumption, and…
- Conditions
- Mastectomy, Rhomboid Intercostal Block, Chronic Pain Following Surgical Procedure for Cancer
- Trial name
- NCT06756048
- Testing
- Rhomboid Intercostal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Koç University
Regional Anesthesia Techniques in Shoulder Surgery
Effectiveness of Field Block Compared With Interscalene Block in Shoulder Surgery
This study will compare two different types of anesthesia used for shoulder surgery. The first method, called an interscalene block, is commonly performed by anesthesiologists and is effective for pain control but may cause side…
- Trial name
- BLOCK-SHOULDER (NCT07173894)
- Testing
- Shoulder Field Block by Orthopedic Surgeon, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Israel
- Volunteers
- 64 people
- Sponsor
- Rabin Medical Center
Analgesia
Analgesic Efficacy of Continuous Infusion of Local Anaesthetic Versus Single-shot Injection Interscalene Block
The aim of this study is to study the analgesic efficacy of a continuous infusion of local anaesthetics for interscalene brachial plexus block after major shoulder surgery in the setting of multimodal analgesia, in order to…
- Trial name
- BIGKIS (NCT04394130)
- Testing
- ropivacaine 0.2%
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Eric Albrecht
Pain, Anesthesia
Intranasal Dexmedetomidine Sedation and Analgesia During Pediatric Emergency Room Procedures
The study objective is to determine if intranasal dexmedetomidine is a safe and effective sedative drug during small painful procedures in the pediatric emergency room.
- Trial name
- INDEXER (NCT03564093)
- Testing
- Intranasal Drug
- Where
- Finland
- Volunteers
- 112 people
- Sponsor
- University of Oulu
Postoperative Pain, Cardiac Surgery
ASPB-PIPB Combination in Cardiac Surgery
Cardiopulmonary bypass surgery is associated with significant postoperative pain, which may adversely affect respiratory function, delay mobilization, prolong hospital stay, and increase postoperative complications.
- Conditions
- Postoperative Pain, Cardiac Surgery, Cardiopulmonary Bypass, Median Sternotomy
- Trial name
- NCT07716943
- Testing
- Combined ASPB and PIPB, Anterior Serratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
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