Clinical trials: Anesthesia and Analgesia
Anesthesia, Analgesia
Transversus Abdominis Plan (TAP) Block for Transcatheter Aortic Valve Implantation (TAVI)
Hemodynamic stability is the main goal of the anesthetic method during Transcatheter Aortic Valve Implantation (TAVI). Pain during the procedure may cause patients to move therefore hemodynamic instability.
- Conditions
- Anesthesia, Analgesia, Block, Aortic Valve Stenosis
- Trial name
- NCT06762288
- Testing
- Ultrasound, Local anesthesia and sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain Management
Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?
The purpose of the study is to determine the effect of a single injection adductor canal block (ACB) on pain scores within 24 hours post total knee arthroplasty (TKA).
- Trial name
- NCT02276495
- Testing
- ACB Control - 20 ml saline injection for ACB, ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block, Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, Irvine
Labor Pain
Labor Analgesia With Ropivacaine and Clonidine
The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural…
- Trial name
- LA (NCT00626977)
- Testing
- ropivacaine, ropivacaine and clonidine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Postoperative Analgesia, Postoperative Pain Management
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
In this study the participants aim to Compare The Effect of Intravenous Combination Dexmedetomidine _ Ketamine versus Dexmedetomidine on Post-Operative Analgesia In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia regarding…
- Trial name
- NCT07330375
- Testing
- Dexmedetomidine, Ketamine, Saline (0.9% NaCl)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pain, Postoperative
Magnesium Sulfate Improves Postoperative Analgesia in Laparoscopic Gynecologic Surgeries
Magnesium sulfate has been reported to improve postoperative pain, but evidence is still controversial. Some studies demonstrated benefits while others concluded that there is no efficacy.
- Trial name
- Magnesium (NCT02508857)
- Testing
- Ketorolac, Magnesium, Saline solution
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Postoperative Pain, Anesthesia
Intravenous Dexamethasone for Ropivacaine Axillary Block
Prospective monocentric double-blind controlled randomised trial Aim is to assess prolonged postsurgical analgesia by intravenous dexamethasone versus intravenous placebo, after ultrasound guided axillary brachial plexus block
- Conditions
- Postoperative Pain, Anesthesia, Forearm Injuries
- Trial name
- ADEXA (NCT02862327)
- Testing
- intravenous dexamethasone, perineural ropivacaine, ultrasound guidance
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hip Arthropathy, Hip Arthrosis
Superiority Randomized Controlled Trial of Ultrasound-guided PENG Block Compared to Surgical Infiltration in the Analgesia of Posterior Total Hip Arthroplasty Surgery
Pain after total hip replacement (THR) surgery is severe. The target population is elderly and comorbid. Level III analgesics are responsible for significant side effects in this population.
- Trial name
- PENGORINF (NCT06257160)
- Testing
- Surgical infiltration, PENG Block ultrasound-guided
- Where
- France
- Volunteers
- 224 people
- Sponsor
- CHU de Reims
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Cervical Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05717361
- Testing
- ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Optic Nerve Sheath Diameter
The Application of Ultrasonic Measurement of Optic Nerve Sheath Diameter in Liposuction Surgery
The main purpose of this study is to investigate the effect of changes in Optic Nerve Sheath Diameter (ONSD) measured at different operating position during Liposuction Surgery.
- Trial name
- NCT06685952
- Where
- China
- Volunteers
- 55 people
- Sponsor
- The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Postoperative Pain
Erector Spinae Plane Block Versus Paravertebral Block in Mastectomy
In this randomized, controlled, observer-blinded study the investigators plan to evaluate ultrasound-guided thoracic paravertebral block (TPVB) and ultrasound-guided thoracic erector spinae plane (TESP) block for postoperative…
- Trial name
- NCT03490006
- Testing
- Erector Spinae Plane Block, Paravertebral Block
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hip Fracture
Comparison of Three Analgesic Strategies for Hip Fracture Surgery
Hip fracture surgery is associated with significant postoperative pain and increased opioid requirements. Regional anesthesia techniques may improve analgesia and reduce opioid consumption.
- Trial name
- HIP-3B (NCT07676734)
- Testing
- Quadro-Iliac Plane Block, Suprainguinal Fascia Iliaca Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Regional Anesthesia, Interscalene Block
is There an Alternative to Ultrasound Guided Interscalene Block?
Interscalene brachial plexus block is the gold standard for perioperative pain management in shoulder surgery. However, this technique would have side effects and potential serious complications.
- Conditions
- Regional Anesthesia, Interscalene Block, Shoulder Surgery
- Trial name
- NCT02397330
- Testing
- bupivacaine, ultrasound, morphine
- Volunteers
- 60 people
- Sponsor
- Tunisian Military Hospital
Inguinal Hernia Unilateral, Postoperative Pain
Quadro-Iliac Plane Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia Repair
The goal of this randomized controlled trial is to learn whether an ultrasound-guided quadro-iliac plane block (QIPB) reduces opioid use and pain after laparoscopic inguinal hernia repair in adults aged 18-65 years.
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain, Opioid Use
- Trial name
- QIPB-LIHR (NCT07878936)
- Testing
- Quadro-iliac plane block
- Volunteers
- 64 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Post Operative Pain
Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Analgesia in Inguinal Hernia Repair
Uncontrolled postoperative pain after inguinal hernia repair increases the incidence of postoperative complications.
- Trial name
- NCT05565365
- Testing
- Transversalis fascia plane (TFP) block, Erector Spinae Plane (ESP) Block
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Assiut University
Pain, Postoperative, Cesarean Section
Bilateral Ultrasound-Guided Transversus Abdominis Plane (Tap) Block and Erector Spinal Plane (Esp) Block
Transversus Abdominis Plane Block (TAPB) is frequently used for the management of postoperative pain in patients undergoing cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section, Erector Spinae Plane Block, Transversus Abdominis Plane Block
- Trial name
- NCT05625009
- Testing
- Procedure/Surgery: Transversus Abdominis Plane Block (TAPB), Procedure/Surgery: Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Cholelithiasis
Endovenous Lidocaine and Serum Cytokines Concentration
Ineffective treatment of postoperative pain may cause organic damage and chronic pain. Nevertheless, opioids, the leading drugs used for this purpose, present side effects that sometimes restrict their usability.
- Trial name
- NCT02363699
- Testing
- Lidocaine, Saline solution
- Volunteers
- 44 people
- Sponsor
- Universidade Federal de Santa Maria
Obstetric Pain
Quality of Postoperative Analgesia and Functional Recovery After Elective Cesarean Delivery
Based on randomization, patients will receive a mixture for spinal anesthesia and will be followed in the following hours for the various outcomes and for functional recovery
- Trial name
- MoFe (NCT06355271)
- Testing
- Fentanyl 1, Fentanyl2, Fentanyl 3
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Pain
Pain Management Following Dental Treatment Under General Anesthesia
The main goal of this study is to test the efficacy of postoperative pain management for cases undergoing extractions of primary teeth under GA using a validated measure.
- Trial name
- NCT06574516
- Testing
- Ibuprofen 200 mg, paracetamol
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Hip Fracture
Analgesia for Positioning Hip Fracture Patients for Spinal Anesthesia
The purpose of this study is to compare two analgesic methods performed preoperatively to assist positioning patients for performance of spinal anesthesia, namely fascia iliaca blockade and intravenous fentanyl.
- Trial name
- NCT02037633
- Testing
- Fentanyl, Fascia iliaca compartment block, ropivacaine
- Where
- Greece
- Volunteers
- 41 people
- Sponsor
- Asklepieion Voulas General Hospital
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