Clinical trials: Anesthetic
Burst Suppression, General Anesthesia
Interrater Variability for the Identification of Anesthetic-induced Burst Suppression EEG
Burst suppression describes a specific EEG pattern that can generally indicate a too deep general anesthesia. The pathophysiology of anesthetic-induced Burst Suppression may be distinctly different from the pathophysiology of…
- Conditions
- Burst Suppression, General Anesthesia, Electroencephalogram
- Trial name
- NCT05508386
- Testing
- MATLAB-based interface, showing 50 EEG traces, classification of the EEG-pattern as Burst Suppression possible, yes, no.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Early Confirmation of Epidural Catheterization
Early Detection of Epidural Onset by Temperature Change
Traditionally, placement of the epidural catheter is based on hand feel of passing through the ligamentum flavum as well as "loss of resistance" while injecting the air through the needle.
- Trial name
- NCT02838056
- Testing
- epidural injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University WanFang Hospital
General Anesthesia
The Affecting Factors on Airway Temperature and Moisture
There is no literature information about the flow rate of fresh gas mixture (air+O2) in the patients who underwent general anesthesia.
- Trial name
- NCT04204746
- Testing
- We will observe and evaluate the temperature and moisture in the respiratory circuit by a thermo-hygrometer.
- Volunteers
- 240 people
- Sponsor
- Selcuk University
Colectomy, Open Surgery
Perioperative Intravenous Nimodipine Trial
The role of perioperative IV administration of nimodipine, an L-type calcium channel antagonist which is capable of crossing the blood-brain barrier, on peri-operative opioid and anesthetics requirements, pain intensity…
- Conditions
- Colectomy, Open Surgery, Pain, Pain, Postoperative
- Trial name
- NCT07048522
- Testing
- Nimodipine, Isotonic Saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Ioannina
Anesthesia, Intravenous
Comparison of Recovery Profile After TIVA Between Remimazolam With Flumazenil and Propofol
This prospective, randomized, single-blinded study is designed to compare the recovery profile between propofol-based total intravenous anesthesia (TIVA) and remimazolam-based TIVA in patients undergoing thyroidectomy.
- Trial name
- NCT05047939
- Testing
- remimazolam-based TIVA, propofol-based TIVA
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
No Disease State or Condition
Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers
The purpose of this study is to determine if the topical application to gingival tissue of the combination of benzocaine and tetracaine has a longer duration of local anesthetic activity than benzocaine alone.
- Trial name
- NCT03233737
- Testing
- One spray CTY-5339-A, One spray CTY-5339-CB, One spray CTY-5339-P
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cetylite Industries
Anesthesia, Local, Intubation, Intratracheal
The Effect of Local Anesthetic Techniques on Hemodynamic Response and Postoperative Sore Throat in Double-Lumen Tubes
This clinical trial aims to determine if different local anesthetic application techniques can reduce postoperative sore throat (POST) and manage hemodynamic responses in adult patients undergoing elective thoracic surgery with…
- Conditions
- Anesthesia, Local, Intubation, Intratracheal, Double-lumen Tube, Sore Throat
- Trial name
- NCT06705595
- Testing
- Tracheo-Spray, Lidocaine Spray on DLT
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Pain, Acute, Rib Fractures
Mid-point to Pleura Transverse Process Block Versus Thoracic Intervertebral Foramen Block
The analgesic effect of continuous mid-point to pleura transverse process block compared to the analgesic effect of continuous thoracic intervertebral foramen block, in patients with multiple rib fractures.
- Conditions
- Pain, Acute, Rib Fractures, Polytrauma
- Trial name
- NCT05348330
- Testing
- Thoracic intervertebral foramen block, Mid-point to pleura transverse process block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Anesthesia, General
Maternal Voice on Anesthetic Emergence Period
Mother spend a large amount of time with their children. It is assumed that mother contributes to their neurological development not only with visual stimuli, but also with auditory stimuli.
- Trial name
- MatherVoice (NCT02860377)
- Testing
- recorded maternal voice, recorded stranger's voice
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Daegu Catholic University Medical Center
Cholelithiases, Cholecystitis
Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration
Laparoscopic cholecystectomy is associated with significant postoperative pain originating from trocar sites, pneumoperitoneum, and visceral irritation.
- Conditions
- Cholelithiases, Cholecystitis, Postoperative Pain
- Trial name
- NCT07582029
- Testing
- Rectus Sheath Block, Local Anesthetic Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Brain Tumor
Assessment of Cognitive Functions and Quality of Life in Patients Undergoing Surgery for Supratentorial Brain Tumor
Primary brain tumors are highly associated with neurocognitive deficit and poor quality of life. There are number of studies indicating that brain tumors and their treatment modalities are often related to cognitive dysfunction.
- Trial name
- NCT02428972
- Testing
- Propofol, Sevoflurane
- Volunteers
- 30 people
- Sponsor
- All India Institute of Medical Sciences
Healthy Volunteers
Local Anesthetic Properties of Neosaxitoxin
The purpose of this study is to evaluate the local anesthetic properties of neosaxitoxin in humans
- Trial name
- NCT00273065
- Testing
- Neosaxitoxin
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chile
Myocardial Ischemia
Optimization of Cardioprotection in Diabetic Patients Undergoing Cardiac Surgery
This study evaluates the myocardial protection against perioperative ischemia comparing two standard anesthetic regimes in diabetic patients undergoing elective cardiac surgery.
- Trial name
- OPT (NCT02407626)
- Testing
- Propofol, Sevoflurane
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- Triemli Hospital
Breast Neoplasms, Pain,Postoperative
Chlorhydrate of Ropivacaine and Breast Cancer Surgery
The aim of the study is to evaluate the effect of local anesthetic (chlorhydrate of ropivacaine) to prevent chronic pain after breast surgery for cancer.
- Trial name
- NCT00370240
- Testing
- Chlorhydrate de Ropivacaine
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Institut Curie
Anesthesia, Local, Nerve Block
Protective Nerve Stimulation in Regional Anesthesia
Peripheral nerve blocks can be conducted with ultrasound, electrical nerve stimulation or landmark technique or a combination of this techniques.
- Conditions
- Anesthesia, Local, Nerve Block, Brachial Plexus Block
- Trial name
- ProNerv (NCT03291691)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Mininimum Effective Anaesthetic Volume of Local Anaesthetic
The Mininimum Effective Anaesthetic Volume of Local Anaesthetic in Ultrasound-guided "Shamrock" Lumbar Plexus Block
The "Shamrock method" is a new ultrasound-guided lumbar plexus block. The aim of the study is to determine the minimum effective volume of ropivacaine 0.5% required to produce an effective lumbar plexus block with this method.
- Trial name
- NCT01956617
- Testing
- lumbar plexus block
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- Oslo University Hospital
Nerve Block, Anesthesia, Local
Cutaneous Anesthesia of the Lateral Femoral Cutaneous Nerve
The purpose of this study is to investigate and describe the anatomical differences in distribution of the blocked area following a perineural LFCN (Lateral Femoris Cutaneous Nerve) block with either 8 ml or 16 ml of Ropivacaine…
- Conditions
- Nerve Block, Anesthesia, Local, Pain, Postoperative, Anatomical Distribution
- Trial name
- NCT03138668
- Testing
- Ropivacaine Injection
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Waste Anesthetic Gas (WAG) Emanating From Patients Post-operative Recovery
Evaluation and Control of WAG in PACU Within Patient and Caregiver Breathing Zone
The purpose of this study is to evaluate anesthetic gas in the PACU within patient and caregiver breathing zones.
- Trial name
- NCT02428413
- Testing
- ISO-Gard Mask, Standard oxygen mask
- Volunteers
- 125 people
- Sponsor
- Teleflex
Post-traumatic Stress Disorder
Ketamine and Prolonged Exposure in PTSD
This study aims at investigating the effectiveness of the drug, Ketamine, in combination with Prolonged Exposure (PE) therapy for people suffering from PTSD.
- Trial name
- NCT03960658
- Testing
- ketamine-enhanced prolonged exposure
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
SARS-CoV-2 Infection
Burn Injuries During COVID-19 Pandemic and Its Influence on Length of Stay
Burn injuries were thought to be difficult to treat during the new corona virus epidemic. Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.
- Trial name
- NCT06330389
- Testing
- Burn Injuries Graft Surgery
- Where
- Qatar
- Volunteers
- 70 people
- Sponsor
- Hamad Medical Corporation