Clinical trials: Anesthetic
Analgesia, Postoperative, Complications of Treatment
Effectiveness of Low Volume Versus High Volume of Local Anesthetic in Ultrasound Guided Combined Supraclavicular and Interscalene Block for Upper Limb Surgery
The aim of this study is to evaluate the effectiveness of low versus high volumes of local anesthetic in ultrasound-guided combined supraclavicular block (SCB) and interscalene block (ISB) for upper limb surgery.
- Trial name
- NCT07028957
- Testing
- Group A; Low volume local anesthetic in Ultrasound guided combined Supraclavicular and Interscalene block for Upper limb surgery, Group B; High volume local anesthetics (30-40ml) ultrasound guided combined Supraclavicular Block (SCB) and Interscalene Block (ISB)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Cancer of Colon, Anesthesia
Anesthesia and Cancer Study: Colon Cancer
This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.
- Trial name
- NCT04259398
- Testing
- Propofol, Sevoflurane
- Where
- 2 sites in South Korea
- Volunteers
- 797 people
- Sponsor
- Seoul National University Hospital
Renal Cell Carcinoma
Anesthesia and Cancer Study: Renal Cell Carcinoma
This study investigates the influence of type of anesthesia on recurrence and survival of renal cell carcinoma in patients undergoing nephrectomy.
- Trial name
- NCT04503148
- Testing
- Propofol, Inhaled General Anesthetics
- Where
- South Korea
- Volunteers
- 562 people
- Sponsor
- Seoul National University Hospital
Sciatic Nerve, Adductor Canal Syndrome
Evaluation of Local Anesthetic Diffusion to the Sciatic Nerve During Adductor Canal Block
Adductor canal block is an effective analgesic technique for major knee surgery. However, the saphenous nerve block is not sufficient to explain this block's efficiency.
- Trial name
- DiffuCAdd (NCT07301476)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-Operative Confusion, Delirium
Tight End-tidal Gas Control During Anesthesia to Decrease Postoperative Delirium Anesthetic Management
Respiratory end-tidal gas control is a fundamental of anesthetic management. The range of end-tidal (ET) O2 and CO2 during the conduct of anesthesia is far outside that found in the awake state.
- Conditions
- Post-Operative Confusion, Delirium, Anesthesia Complication
- Trial name
- NCT04406350
- Testing
- Intraoperative tight control of respiratory end-tidal gases
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Infusion Site Anaesthesia
Ultrasound and Neuraxial Anesthesia in Pregnancy
Ultrasonography is routinely performed during pregnancy by obstetricians to visualize the fetus, making patients familiar and comfortable with its usage.
- Trial name
- USPREG (NCT02392533)
- Testing
- Education
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Chicago
General Anaesthesia
Evaluation of Analgesia Nociception Index (ANI) During Propofol/Remifentanil and Sevoflurane/Remifentanil Anesthesia
The aim of this prospective randomized study was to evaluate the ability of the new Analgesia Nociception Index ANI, derived by heart rate variability, to detect painful stimulation during either propofol or sevoflurane…
- Trial name
- NCT01522508
- Testing
- tetanic stimulation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Schleswig-Holstein
Postoperative Pain
Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates
This study is being done to try to learn more about how a child's body breaks down bupivacaine, a local anesthetic medication that is being used for pain control.
- Trial name
- NCT01557985
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Phantom Limb, Leg Amputation
Leg Amputation and Continuous Sciatic Nerve Block
Analgesia following leg amputation is based on morphine administration. For elderly patients of ASA physical status 2 or 3, morphine sparing is possible when perinervous block techniques are used.
- Trial name
- CAPDAF (NCT00427947)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Bordeaux
Myofascial Pain Syndrome of Neck
Comparison of the Efficacy of Prolotherapy Injection Therapy & Local Anesthetic Injection Therapy.
Myofascial pain syndrome is a disease characterized by pain over the trigger point in a taut muscle band. After the correct diagnosis is made, many treatment methods can be applied.
- Trial name
- NCT05239091
- Testing
- Dextrose solution, Lidocain
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Pain
Comparison of Two Different Methods of Delivering Local Analgesia During Intra-articular Corticosteroid Injections in Children With Juvenile Idiopathic Arthritis
Chronic arthritis (inflammation of joints) in children is known as Juvenile Idiopathic Arthritis (JIA). Often, to control the swelling and to help reduce the pain in the joint, medications (steroids) are injected into the joint.
- Trial name
- NCT00465504
- Testing
- iontophoresis
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Arthropathy of Knee Joint
Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block
To evaluate an analgesic effect without basal administration of local anesthetics for patient-controlled femoral nerve block (with sciatic nerve block) after total knee arthroplasty.
- Trial name
- NCT01198340
- Testing
- PC-FNB with basal administration of local anesthetics, PC-FNB without basal local anesthetics
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Okayama University
Pain, Postoperative
Lidocaine as an Anesthetic Adjuvant in Liver and Gastric Laparoscopic Surgery
The aim is to analyze the effect of intravenous lidocaine administration on postoperative opioid use in patients undergoing upper abdominal cancer surgery.
- Trial name
- NCT04584749
- Testing
- Lidocaine Iv
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Hip Arthroplasty
Anesthetic Methods and Gene Expression Profile
The study will analyze differentially regulated genes involved in oxidative stress and toxicology in peripheral blood mononuclear cells (PBMCs) of patients who underwent arthroplasty under three different anesthetic methods.
- Trial name
- GeSTA (NCT03585647)
- Testing
- hip arthroplasty
- Where
- Italy
- Volunteers
- 99 people
- Sponsor
- University of Bologna
Difficult or Failed Intubation, Voice
The Voice Analysis as a Preoperative Prediction Method of a Difficult Airway
Before an anesthetic procedure, airway management is essential to ensure adequate ventilation and breathing of the patient during the entire surgical process.
- Conditions
- Difficult or Failed Intubation, Voice, Laryngoscopy
- Trial name
- NCT04259021
- Where
- Spain
- Volunteers
- 722 people
- Sponsor
- Fundacion Dexeus
Comparison of Onset Time
Onset Time of Brachial Plexus Block Using Local Anaesthetic Diluted With 0.9% Saline vs 5% Dextrose
Regional anesthesia employs the use of local anesthetics (LA) to block specific nerves to enable pain free surgery to be performed, or for intra and post operative pain relief.
- Trial name
- NCT01815944
- Testing
- 0.75% Ropivacaine, Normal saline, Dextrose 5%
- Where
- Malaysia
- Volunteers
- 55 people
- Sponsor
- University of Malaya
Knee Stiffness After Total Knee Arthroplasty
Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia
The purpose of this study is to determine if changing the type of anesthesia improves the outcomes of manipulation and pain control after the procedure.
- Trial name
- NCT07348614
- Testing
- Spinal Anesthesia, General Anesthesia, Propofol
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Duke University
Transformed Migraine, Chronic Daily Headache
Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with traditional antidepressant Amitriptyline / Elavil.
- Trial name
- NCT02090998
- Testing
- SPG Block with 5% Lidocaine gel, Amitriptyline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Aortic Stenosis
Association of Type of Anesthetic and Outcomes in Transfemoral Aortic Valve Replacement
This study proposes to perform a descriptive analysis and pilot observational study looking at the types and quantity of anesthetic agents used and their associations with outcomes among patients scheduled to receive transfemoral…
- Trial name
- NCT02786264
- Testing
- Dexmedetomidine with propofol, Propofol
- Volunteers
- 186 people
- Sponsor
- Yale University
Post Operative Pain
Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block
Prospective, patient-blinded study utilizing a novel Continuous Reassessment Method that concomitantly considers both block success and block side effects (lung dysfunction) for brachial plexus nerve blocks.
- Trial name
- NCT05868993
- Testing
- Dose of 0.5% Ropivacaine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute