Clinical trials: Anesthetic Depth
Strabismus
Anesthetic Depth and the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery
This study evaluates the association between the depth of general anesthesia and the occurrence of emergence agitation (EA). The investigators hypothesized that optimal level of anesthetic depth could decrease the incidence of EA…
- Trial name
- NCT02521259
- Testing
- BIS
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Bundang Hospital
Pain, Postoperative
Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
Effective post surgical pain control in patients undergoing unilateral deep inferior epigastric perforator (DIEP) free flap reconstruction.
- Trial name
- NCT04284930
- Testing
- Depobupivacaine, OnQ pump, 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Mental Function
Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
The purpose of this study is to see if mental functions take place during different levels of anesthesia. The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia, and to…
- Trial name
- NCT05495945
- Testing
- Low-intensity focused ultrasound pulsation (LIFUP), Functional Magnetic Resonance Imaging (fMRI) using Propofol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Atrial Fibrillation, Atrial Flutter
Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current Cardioversion
A randomized, open-blinded, prospective study to evaluate the timeliness and safety of direct current cardioversion (DCCV) when using methohexital when compared to the more often used propofol.
- Trial name
- NCT04187196
- Testing
- Propofol, Methohexital
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Wake Forest University Health Sciences
Anesthesia, Surgery
Sedline EEG Guided Depth of Anesthesia
The purpose of our study is to determine if monitoring sedation (how asleep patients are under general anesthesia) using a device called a Sedline Monitor affects the amount of anesthesia patients receive.
- Trial name
- NCT05051982
- Testing
- Sedline EEG in View
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Indiana University
Neuromuscular Blockade, Rocuronium
Impact of Deep Versus Standard Muscle Relaxation on Intra-operative Safety
Muscle relaxants are routinely applied during anesthesia to facilitate endotracheal intubation and to improve surgical working conditions.
- Conditions
- Neuromuscular Blockade, Rocuronium, Anesthetics, Anesthesia Complication
- Trial name
- EURORELAX (NCT04124757)
- Testing
- Deep neuromuscular block
- Where
- 8 sites in France, Italy and 2 more
- Volunteers
- 731 people
- Sponsor
- Leiden University Medical Center
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Deep Sedation, Anesthesia, General
Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia
The study hypothesizes that adding 60% nitrous oxide to a steady state sevoflurance or propofol anesthetic will lead to a decrease in both BIS and Entropy indices during a constant level of surgical stimulus
- Trial name
- N20 (NCT00717574)
- Testing
- Sevoflurane group, Propofol group
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Oklahoma