Clinical trials: Anesthetics, Inhalation
Intensive Care Ventilation
Pressure Support Ventilation With the Anesthetic Conserving Device
Sevoflurane inhalational anesthetic has got pulmonary effects such as bronchodilatation. These effects could be of interest in intensive care patients ventilated in pressure support ventilation mode.
- Trial name
- NCT01017744
- Testing
- Anesthetic Conserving Device
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Clermont-Ferrand
Lung Diseases, Total Intravenous Anesthesia
Effects of Adding Different Drugs for Preventing Cough Induced by Bronchoscopic Spraying of Local Anesthetics
Cough is the most unwanted response during bronchoscopic interventions for hemodynamic instability, hypoxemia, and interruption of interventions.
- Conditions
- Lung Diseases, Total Intravenous Anesthesia, Bronchoscopic Interventions
- Trial name
- NCT05072236
- Testing
- bronchoscopic insertion
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- National Taiwan University Hospital
Oxidative Stress, Morbid Obesity
A Comparison of the Effects of Desflurane and TIVA on Antioxidant System in Morbidly Obese Patients
With the development of technology, the safety of anesthesia devices and the progression of monitoring techniques affect the anesthetic management.
- Trial name
- OxSys (NCT03814577)
- Testing
- Total Antioxidant Status, Total Oxidant Status, Bispectral Index
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Inonu University
Lung Cancer, Progression, Disease
The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary early lung cancer.
- Conditions
- Lung Cancer, Progression, Disease, Anesthesia
- Trial name
- NCT05663242
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Airway Reflexes, Protective, Recovery After Neuromuscular Block
Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Protective airway reflexes may be impaired in the postoperative period, creating the potential for aspiration of gastric contents, even after a patient exhibits appropriate response to command.
- Conditions
- Airway Reflexes, Protective, Recovery After Neuromuscular Block, Anesthetic Recovery
- Trial name
- NCT01199237
- Testing
- Sevoflurane, Desflurane, Rocuronium
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- University of California, San Francisco
Laryngeal Masks
Comparative Evaluation of Ambu AuraGain Laryngeal Mask and Proseal Laryngeal Mask Airway
Comparison of two different supraglottic airway devices i.e., the ProSeal Laryngeal Mask Airway (PLMA) and Ambu AuraGain, a third generation laryngeal mask Airway.
- Trial name
- NCT03139292
- Testing
- ProSeal Laryngeal Mask Airway, AmbuAuraGain Laryngeal Mask Airway
- Where
- India
- Volunteers
- 160 people
- Sponsor
- Tata Main Hospital
DNA Damage
The Effect of Desfluran On Global Dna Methylation
The purpose of this study is to demonstrate the molecular effect of desflurane on DNA by measuring the global DNA methylation level in patients under going lumbar spinal stenosis surgery under general anesthesia.
- Trial name
- NCT05111717
- Testing
- Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Muğla Sıtkı Koçman University
Coronary Artery Disease, Anesthesia
Influence of Oxygen on Perioperative Outcome in Patients Undergoing General Anaesthesia for Elective Non-cardiac Surgery
The purpose of this study is to investigate the impact of supraphysiologic oxygen (hyperoxia) on myocardial function in anaesthetized patients undergoing non-cardiac vascular surgery.
- Trial name
- Promise-O2 (NCT04808401)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
General Anesthesia, Children
Effects of Binaural Beats on Inhaled Anesthetic Requirements During General Anesthesia in Pediatric Patients
The hypothesis of this study is that continuously delivering binaural beats with a phase difference corresponding to the slow-delta frequency band during anesthesia in pediatric patients can clinically and significantly reduce…
- Trial name
- NCT06979206
- Testing
- Application of Binarual Beat
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Waste Anesthetic Gas (WAG) Emanating From Patients Post-operative Recovery
Evaluation and Control of WAG in PACU Within Patient and Caregiver Breathing Zone
The purpose of this study is to evaluate anesthetic gas in the PACU within patient and caregiver breathing zones.
- Trial name
- NCT02428413
- Testing
- ISO-Gard Mask, Standard oxygen mask
- Volunteers
- 125 people
- Sponsor
- Teleflex
Respiration, Artificial
The Correlational Study of PPV in Various VT in Mechanically Ventilated Patients
Mesquida, J et al showed there was a significant linear correlation between pulse pressure variations under tidal volume 6 ml/kg and 8 ml/kg in patients after the resuscitation phase of severe sepsis and septic shock.
- Trial name
- NCT01950949
- Testing
- 300 ml Hydroxyethyl Starch 130/0.4 and Sodium Chloride Injection infusing in 15 minutes if PPV under VT 8 ml/kg was larger than 13% in the initial investigation
- Volunteers
- 69 people
- Sponsor
- Yi Liu
Surgery, Anesthesia
Evaluation of a Novel Portable Capnograph (MARIE) in Adult Postoperative Patients
Postoperative respiratory complications are common and sometimes hard to detect early. Desaturation is a late sign of reduced minute ventilation, especially if the patient is on supplemental oxygen, and measurement of arterial or…
- Conditions
- Surgery, Anesthesia, Postoperative Care, Respiration Rate Detection
- Trial name
- NOVOCAP-Postop (NCT07178236)
- Testing
- MARIE
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Malin Jonsson Fagerlund
Anaesthesia, Intraocular Pressure
Effects Of Anaesthesia on Intraocular Pressure in Robotic Prostate Surgery
Robot-assisted surgery is now commonly used to treat prostate cancer. This type of surgery, called robot-assisted prostatectomy, helps doctors operate more precisely and allows patients to heal faster.
- Conditions
- Anaesthesia, Intraocular Pressure, Trendelenburg Position, Robot Assisted Laparoscopic Radical Prostatectomy
- Trial name
- NCT07033442
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Volunteers
- 60 people
- Sponsor
- Ataturk Training and Research Hospital
Anesthesia
Reducing the Carbon Footprint Through Education on the Effects of Inhalation Anesthetics on Global Warming
Inhalation anesthetics, such as desflurane, are identified as contributors to global warming, with the European Union planning to ban desflurane in 2026 due to its impact.
- Trial name
- NCT06084039
- Where
- South Korea
- Volunteers
- 4,478 people
- Sponsor
- Pusan National University Yangsan Hospital
Opioid Use, Bariatric Surgery Candidate
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery.
- Conditions
- Opioid Use, Bariatric Surgery Candidate, TCI Eleveld, Obesity
- Trial name
- NCT07568938
- Testing
- opioid free anesthesia, Opiod Free Anesthesia with TCI ELEVELD
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Dental Anxiety, Anxiety Disorder
Lavender Oil Inhalation Help to Overcome Dental Anxiety Among Children
The purpose of this study is to investigate the impact of lavender oil (Lavandula angustifolia) on anxiety, pain and vital signs (blood pressure, heart rate and saturation) among children planned to undergone surgical…
- Conditions
- Dental Anxiety, Anxiety Disorder, Aromatherapy
- Trial name
- NCT04115891
- Testing
- Anxiety scale, Pain scale - 1, Pain scale - 2
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Atelectasis, General Aneshesia
Effects of Anesthesia on Atelectasis
We know that respiratory functions of patients are affected under general anaesthesia. Although there are many underlying causes of ventilation-perfusion mismatch in the airways, the main cause is atelectasis during general…
- Trial name
- NCT06790901
- Testing
- LUNG ULTRASOUND
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Inhalation; Gas
Sevoflurane Wash in Method Using Conventional Flows Versus Low Flows of 0.5L
The goal of this observational study is to to evaluate a technique of initiating Sevoflurane low-flow anesthesia which is simple, has a quick wash-in and minimises gas consumption without compromising the safety when compared to…
- Trial name
- NCT06209112
- Testing
- Sevoflurane
- Where
- Oman
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Royal Hospital, Oman
Cholecystitis, Chronic
Effect of Sevoflurane and Desflurane on Heme Oxygenase-1 Expression in Elective Cholecystectomy
General anesthesia is routinely administered to patients who undergo elective cholecystectomy. The most commonly used inhalation agents during general anesthesia are sevoflurane and desflurane.
- Trial name
- NCT06457958
- Testing
- Sevoflurane Group, Desflurane Group
- Where
- Turkey (Türkiye)
- Sponsor
- Kocaeli City Hospital
Postoperative Sleep Quality, General Anesthesia
The Effects of Intravenous Anesthetics and Inhaled Anesthetics on Patients' Postoperative Sleep
Adequate sleep is necessary for physical and mental health of human being. Although surgery and anesthesia techniques have improved in resent years, postoperative sleep disturbance remains a challenging problem in surgical…
- Conditions
- Postoperative Sleep Quality, General Anesthesia, Propofol, Sevoflurane
- Trial name
- NCT04123249
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Yanchao Yang