Clinical trials: Aneurysm Aortic
Thoracic Aortic Aneurysm
Effective Treatments for Thoracic Aortic Aneurysms (ETTAA Study): A Prospective Cohort Study
This is a prospective observational cohort study that will collect data from the point of referral through to secondary care, aiming for 3 years median follow-up (range 1-5 years).
- Trial name
- ETTAA (NCT02010892)
- Testing
- Stent Grafting (ESR), Open Surgery (OSR)
- Where
- United Kingdom
- Volunteers
- 2,200 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Aneurysm Aortic, Aneurysm Aortic Root
Strength Tracking From Wall Tichness Over Aortic Biomechanics (STORM)
The aim of the study is to analyse the resected portion of aneurysmatic ascending aorta in order to assess its strength to rupture, standardise the various measurements performed within the lab and try to correlate these…
- Trial name
- STORM (NCT07453251)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Policlinico S. Donato
Thoracoabdominal Aortic Aneurysm, Endovascular Repair of Aortic Aneurysm
ANATOMICAL FEASIBILITY OF BRAILE STANDARD BRANCHED ENDOGRAFT
The objective of this retrospective observational study is to evaluate the theoretical anatomical suitability of the new Braile off-the-shelf multi-branched endograft in patients with thoracoabdominal aneurysm.
- Conditions
- Thoracoabdominal Aortic Aneurysm, Endovascular Repair of Aortic Aneurysm, Vascular Diseases, Aortic Diseases
- Trial name
- BMETA (NCT07118995)
- Testing
- Analysis of preoperative CTA
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Braile Biomedica Ind. Com. e Repr. Ltda.
Abdominal Aortic Aneurysm
Effect of Pre-operative Exercise in Abdominal Aortic Aneurysms (AAA) Patients.
An aneurysm is a permanent and localized dilatation of an artery usually more than 50% of its normal diameter. Abdominal Aortic Aneurysms (AAA) is an aneurysm of the main artery of abdomen and affects 5% of men aged 65-74 years.
- Trial name
- NCT01062594
- Testing
- Supervised exercise, Role of exercise, Supervised exercise program
- Where
- United Kingdom
- Volunteers
- 124 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Abdominal Aortic Aneurysm
Hellenic Registry of Ovation Alto™ Abdominal Stent Graft System
This is a Hellenic Registry including both retrospective and prospective subjects receiving the Ovation Alto™ Abdominal Stent Graft System ("Ovation Alto™ Abdominal Stent Graft System Post-Market Study") in the treatment of…
- Trial name
- NCT05172830
- Testing
- Ovation Alto™ Abdominal Stent Graft System
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Larissa University Hospital
Renal Failure
A Comparison of Renal Perfusion in Thoracoabdominal Aortic Aneurysm (TAAA) Repair
The purpose of this randomized trial was to determine whether renal perfusion with cold blood provides better protection against renal ischemia than perfusion with cold crystalloid in patients undergoing TAAA repair with left…
- Trial name
- NCT00691756
- Testing
- Cold blood renal perfusion, Cold crystalloid renal perfusion
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Baylor College of Medicine
Infrarenal Aortic Aneurysm
Patient-specific Virtual Reality Rehearsal Prior to EVAR: Influence on Technical and Non-technical Operative Performance
Ongoing technological advances, especially in the field of image processing, have refined medical simulations to offer life-like replications of medical and surgical procedures in a variety of specialties.
- Trial name
- NCT01632631
- Where
- 3 sites in Belgium, Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Aortic Aneurysm, Aortic Dissection
Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study
The registry study aims to determine serial biomarkers to diagnosis and prognosis of aortic aneurysm/aortic dissection.
- Trial name
- NCT03233087
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Vascular Diseases
Prospective/Retrospective Registry of the E-vita OPEN PLUS Stent Graft System in France
The FEOR registry is undertaken to examine the real-world data of patients that were treated with the E-vita OPEN Plus Stent Graft System under routine care in France.
- Trial name
- FEOR (NCT04058691)
- Testing
- Surgical repair
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- JOTEC GmbH
Aortic Diseases, Thoracic Aortic Aneurysm
Mid- and Long-term Outcomes of Custom-made Aortic Devices
This study aims to evaluate mid- and long-term outcomes after Thoracic endovascular aortic repair (TEVAR) with custom-made devices.
- Trial name
- NCT05777460
- Testing
- Thoracic endovascular aortic repair (TEVAR)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Aortic Aneurysm and Dissection
A Prospective Study of Discomfort Symptoms in Patients With Aortic Disease After Endovascular Intervention
The incidence and severity of post-procedural discomfort were evaluated in patients undergoing endovascular repair for aortic disease across six symptom-related dimensions: immobilization-related issues, puncture site discomfort…
- Trial name
- NCT07114185
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal
Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair
The purpose of this study is to compare two intravenous anesthetics, remimazolam and propofol, for their effects on intraoperative hemodynamic stability in patients undergoing thoracic or abdominal endovascular aortic repair.
- Conditions
- Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal, Intraoperative Hypotension, Hemodynamic Instability During Anesthesia
- Trial name
- NCT07806006
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Aortic Dissection
Surgery for Delay-recognized or Defer-operated Type A Aortic Dissection
From November 2004 to June 2020, there were more than 200 patients with acute TAAD patients who underwent aortic surgery at our hospital.Of all the patients in the study period, there were 34 patients (defined as study group) who…
- Trial name
- NCT05044494
- Testing
- non-prompt surgery
- Volunteers
- 68 people
- Sponsor
- Mackay Memorial Hospital
Aortic Arch, Aortic Arch Aneurysm
Outcome of a Triple Inner Branched Aortic Arch Stentgraft. A Prospective, Multicenter Registry.
Outcome of a triple inner branched aortic arch stentgraft. A prospective, mulitcenter registry.
- Conditions
- Aortic Arch, Aortic Arch Aneurysm, Dissection of Aortic Arch, Triple Branch
- Trial name
- triple_branch (NCT05530304)
- Testing
- Triple inner branched arch stentgraft
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Muenster
Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm)
Quick Yielding Modified Short-Distance Fenestration Technique for the Treatment of Complex Aortic Arch Diseases: a Multicenter Single-Arm Objective Performance Criteria Trial(QYM-Tech Study)
Background: This study investigates the safety and efficacy of a novel surgical approach combining thoracic endovascular aortic repair (TEVAR) and in situ fenestration reconstruction of supra-aortic branches using the Quick…
- Conditions
- Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm), Thoracic Pseudoaneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT06639243
- Testing
- QYM Technique
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Vascular Aneurysm
A PMCF Study in Patients With Infrarenal Aortic Aneurysm Treated With the E-tegra Stent Graft System
The EASY post-market clinical follow-up study is undertaken to demonstrate safety and clinical performance of the E-tegra Stent Graft System used in endovascular treatment of infrarenal aortic aneurysm.
- Trial name
- EASY (NCT04765176)
- Testing
- Endovascular Repair
- Where
- Netherlands
- Volunteers
- 151 people
- Sponsor
- JOTEC GmbH
Ehlers-Danlos Syndrome, Vascular Type
Angiotensin II Receptor Blockade in Vascular Ehlers Danlos Syndrome (ARCADE)
This study aims to verify the hypothesis that patients with Vascular Ehlers Danlos syndrome (vEDS) should benefit of the blockade of angiotensin (Ang) II noxious effects on their vasculature affected by a defect in type III…
- Trial name
- ARCADE (NCT02597361)
- Testing
- Irbesartan
- Where
- 15 sites in France
- Volunteers
- 61 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aortic Arch Aneurysm
Silent Brain Infarction After Endovascular Arch Procedures
This is the largest study to evaluate incidence and distribution of silent cerebral infarction (SBI) following endovascular repair for disease of the aortic arch.
- Trial name
- NCT04489277
- Testing
- Endovascular Arch Procedures
- Where
- 2 sites in France, Germany
- Volunteers
- 91 people
- Sponsor
- Medical University of Vienna
Aortic Dissection, Pregnancy Related
Clinical Features, Outcomes, and Therapeutics of Pregnancy-Related Aortic Dissection
Aortic dissection in pregnancy represents a lethal risk to both the mother and fetus, it has yet to yield the optimal therapeutic strategy.
- Trial name
- NCT05501145
- Testing
- cesarean section and aortic repair
- Where
- 4 sites in China
- Volunteers
- 75 people
- Sponsor
- Nanjing Medical University
Abdominal Aortic Aneurysm
PET Imaging of MMP Activation in AAA: Clinical Component
A first-in-human evaluation of [64Cu]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale)…
- Trial name
- PET AAA (NCT07473102)
- Testing
- Cu-64-RYM2, PET imaging using Cu-64
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine