Clinical trials: Angina Pectoris With Normal Coronary Arteriogram
Obesity
Interdisciplinary Intervention in Patients With Obesity and Other Metabolic Diseases
The aim of the research study will be assess the effectiveness of a long-term interdisciplinary lifestyle in many aspects including food intake, psychological symptoms, physical activity habits, energy expenditure, body…
- Trial name
- NCT02573688
- Testing
- Interdisciplinary Therapy
- Where
- Brazil
- Volunteers
- 87 people
- Sponsor
- Federal University of São Paulo
Peripheral Artery Disease, Coronary Disease
Evaluation of Patients With Known or Suspected Heart Disease
In this study researchers will admit and evaluate patients with known or suspected heart disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute (NHLBI).
- Conditions
- Peripheral Artery Disease, Coronary Disease, Diabetes and Heart Failure, Dilated Cardiomyopathy
- Trial name
- NCT00001313
- Where
- 2 sites in United States
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Dysmetabolic Iron Overload Syndrome, Genetic Hemochromatosis
Effects of Polyphenols on Iron Absorption in Iron Overload Disorders.
Dysmetabolic iron overload syndrome and genetic hemochromatosis are frequent causes of iron overload. Polyphenols are efficient iron-chelators.
- Conditions
- Dysmetabolic Iron Overload Syndrome, Genetic Hemochromatosis, Iron Absorption, Polyphenols
- Trial name
- POLYFER (NCT03453918)
- Testing
- polyphenols
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Clermont-Ferrand
HIV Infections, Cardiovascular Diseases
Implementation and Effectiveness of Physical Activity to Prevent Disability in HIV-infected Adults Older Than 50 From Côte d'Ivoire
The overall objective of this research is to provide evidence on the effectiveness and implementation of two strategies deliver a structured programme of physical activity (PA) people living with HIV older than 50 years from…
- Conditions
- HIV Infections, Cardiovascular Diseases, Insulin Resistance Syndrome X
- Trial name
- VIRAGE+ (NCT06139497)
- Testing
- Physical activity programme, Home-based physical activity
- Where
- 2 sites in Côte d’Ivoire
- Volunteers
- 180 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Cardiovascular Diseases, Heart Diseases
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
This study will investigate the separate and combined effects of aerobic and resistance training on cardiovascular risk factors in overweight men and women with mild to moderate dyslipidemia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Hyperlipidemia
- Trial name
- STRRIDE2 (NCT00275145)
- Testing
- Resistance Training, Aerobic Exercise, Combo
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Duke University
Physical Activity, Endothelial Dysfunction
Recreational Physical Activity and Cardiometabolic Profile
The purpose of present study was to investigate the effect of 10 weeks of recreational physical activity program on the irisin levels, progenitor endothelial cells and cardiometabolic profile in healthy children.
- Conditions
- Physical Activity, Endothelial Dysfunction, Metabolic Syndrome x
- Trial name
- NCT02982967
- Testing
- Physical Activity
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hypertension, Metabolic Syndrome X
Clinical EvaluatioN of TElmisartan-based Antihypertensive Regimen
To determine the efficacy and safety of telmisartan-based treatment among patients with metabolic syndrome in actual setting in Philippines.
- Trial name
- NCT00613314
- Where
- 122 sites in Philippines
- Volunteers
- 15,268 people
- Sponsor
- Boehringer Ingelheim
Metabolic Syndrome X
Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial
The purpose of this study is to determine whether telmisartan and/or a low-glycemic index diet are effective in reducing intra-myocellular lipid (muscle fat) content.
- Trial name
- NCT00147264
- Testing
- Low-Glycemic Index Diet vs. Control Diet
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- McMaster University
Insulin Resistance, Metabolic Syndrome x
Insulin Resistance Study
The purpose of this study is to evaluate how often patients with hepatitis C infection have abnormalities of sugar and fat utilization.
- Trial name
- IR (NCT00614757)
- Testing
- N-acetylcysteine 20% 4ml, N-acetylcysteine 20% in 4 ml
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Functional MRI Biomarkers of Cognitive Decrements in Diabetes
The exact neuronal mechanism underlying the cognitive decline associated with diabetes mellitus type 2 (DM2) still remains to be elucidated.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Mild Cognitive Impairment
- Trial name
- NCT01705210
- Where
- Netherlands
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Factor XIII Deficiency, ST-Elevation Myocardial Infarction
Factor XIII and Other Biomarkers in ST Segment Elevation Myocardial Infarction
In medical practice, a combination of clinical exam, electrocardiograms, circulating biomarkers, and imaging is used to gain insights on the prognosis after myocardial infarction.
- Conditions
- Factor XIII Deficiency, ST-Elevation Myocardial Infarction, Myocardial Haemorrhage, Coronary Microvascular Disease
- Trial name
- eXIST (NCT03523624)
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Padova
Metabolic Syndrome X
Walnut Intervention on Metabolic Syndrome (WIMS)
The purpose of this study is to determine whether a daily supplement of 30 grams of walnut is effective in the treatment of metabolic syndrome (MetS).
- Trial name
- WIMS (NCT00742742)
- Testing
- healthy life style education
- Where
- China
- Volunteers
- 189 people
- Sponsor
- Chinese Academy of Sciences
Overweight, Metabolic Syndrome X
Health of Young European Families and Fish Consumption
This is a controlled, randomized, intervention trial (CRIT) with 20-40 year old overweight individuals (n = 320) across Europe in order to distinguish between biologically active components of seafood, i.e., seafood proteins and…
- Conditions
- Overweight, Metabolic Syndrome X, Bone Resorption
- Trial name
- NCT00315770
- Testing
- weight loss diets for young adults
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Coronary Artery Disease, Microvascular Angina
Coronary Thermo-dilution Derived Flow-indices in Chronic Coronary Syndrome
Patients scheduled for elective coronary angiography due to chronic coronary syndrome are recruited at admission to hospital before the coronary anatomy is known.
- Conditions
- Coronary Artery Disease, Microvascular Angina, Coronary Microvascular Dysfunction
- Trial name
- NCT06306066
- Where
- Sweden
- Volunteers
- 505 people
- Sponsor
- Karolinska Institutet
Angina, Stable, Coronary Vasospasm
CORonary MICrovascular Angina (CorMicA)
Angina is form of chest pain that is due to a lack of blood to the heart muscle. Angina is commonly triggered by stress and exertion, and is a common health problem worldwide.
- Conditions
- Angina, Stable, Coronary Vasospasm, Coronary Circulation, Coronary Syndrome
- Trial name
- CorMicA (NCT03193294)
- Testing
- Stratified medicine involving a diagnostic intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 151 people
- Sponsor
- NHS National Waiting Times Centre Board
Insulin Resistance, Metabolic Syndrome X
The Health Effects of Blueberry Anthocyanins in Metabolic Syndrome (the CIRCLES-study)
The purpose of this study is to determine the dose-dependent impact of 6 month freeze-dried blueberry powder intake on insulin sensitivity and resistance, cardiovascular disease risk factors, and lung and cognitive function in…
- Trial name
- CIRCLES (NCT02035592)
- Testing
- Full dose blueberry, Half dose blueberry, Control
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 144 people
- Sponsor
- University of East Anglia
Microvascular Angina, Hypertension
Effects of Intensive Long-Term Vasodilation in Hypertensive Patients With Microvascular Angina Pectoris
The purpose of this study is to determine if long-term vasodilatory treatment is more effective than the standard treatment in hypertensive patients with microvascular angina pectoris
- Trial name
- NCT00424801
- Testing
- Lercanidipine, Valsartan, Nicorandil
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Microvascular Angina
Effect of ACE-Inhibition on Microvascular Function in Women With Assessed Microvascular Dysfunction
The aim of this study is to explore effects of long term treatment with ACE-inhibitor on the small vessel function assessed by coronary flow reserve (CFR) by transthoracic echocardiography and flow mediated dilation in…
- Trial name
- NCT02525081
- Testing
- Ramipril (ACE-inhibitor)
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- Bispebjerg Hospital
Coronary Microvascular Angina, Macitentan
Evaluation of the Efficacy of MACitentan in the Treatment of CoronaryMICrovascular Angina (MACMIC)
Coronary microvascular angina (MVA) significantly reduces quality of life and increases the risk of heart problems in patients with angina. Unfortunately, there are no effective treatments available yet.
- Trial name
- NCT06811831
- Testing
- Macitentan 10 mg tablet, once daily.
- Where
- China
- Volunteers
- 30 people
- Sponsor
- China-Japan Friendship Hospital
Obesity, Diabetes Mellitus
Activating Brown Adipose Tissue Through Exercise
The energy burning capacity of brown adipose tissue makes it an attractive target for anti-obesity therapies. Sympathetic nervous system (SNS) is the classical regulator of brown adipose tissue; however, recent findings show a…
- Conditions
- Obesity, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- ACTIBATE (NCT02365129)
- Testing
- Exercise training based on recommendations for adults (WHO)
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada