Clinical trials: Anginal Pain
Healthy
Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets
This study will determine whether and how nitrites and nitrates in the diet affect the level of nitric oxide gas that is breathed out in air.
- Trial name
- NCT00027157
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Stenosis, Periodontal Diseases
Periodontal Disease, Inflammation and Acute Coronary Syndromes
Recent studies have shown that the systemic inflammation caused by periodontal disease (PD) can determine important changes in the coronary arteries, favoring atherosclerosis progression and development of acute coronary…
- Conditions
- Coronary Stenosis, Periodontal Diseases, Acute Coronary Syndrome, Non-ST Elevation Myocardial Infarction
- Trial name
- ATHERODENT (NCT03395041)
- Testing
- cardiac imaging tests
- Where
- Romania
- Volunteers
- 149 people
- Sponsor
- Cardio Med Medical Center
Stable Angina
Impact of Spiroergometer Parameters as Diagnostic Marker of Cardiac Ischemia in Pts. With Stable Angina Compared to FFR.
In Patients with stable Angina pectoris CCS 1-3 exercise testing for ischemia detection is widely used despite the known limitations. Measurement of the FFR is invasive but gold standard for Ischemia detection.
- Trial name
- ADVANCE (NCT04450459)
- Testing
- ergospirometer test
- Where
- Germany
- Volunteers
- 121 people
- Sponsor
- Jena University Hospital
Acute Myocardial Infarction, Angina Pectoris
Effects of Telmisartan on Ischemic Cardiovascular Events in High-risk Hypertensive Patients
This study is aimed to investigate whether treatment with Telmisartan is more effective than Candesartan in reducing the ischemic cardiovascular events in high-risk patients with cardiovascular disease.
- Conditions
- Acute Myocardial Infarction, Angina Pectoris, Myocardial Ischemia, Acute Coronary Syndrome
- Trial name
- KCPS (NCT00863980)
- Testing
- Micardis (Telmisartan), Blopress (Candesartan)
- Where
- 32 sites in Japan
- Volunteers
- 1,500 people
- Sponsor
- Kyoto Prefectural University of Medicine
Coronary Microvascular Disease, Ischemic Heart Disease
A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction
Among patients with stable ischemic heart disease who are referred for coronary angiography, a substantial proportion have non-obstructive coronary artery disease (CAD).
- Conditions
- Coronary Microvascular Disease, Ischemic Heart Disease, Myocardial Ischemia
- Trial name
- NCT03537586
- Testing
- Bivalirudin, Adenosine, Heparin
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- NYU Langone Health
Angina Pectoris, Cardiovascular Diseases
Women's Ischemia Syndrome Evaluation (WISE)
To evaluate innovative diagnostic methods that will improve the diagnostic reliability of cardiovascular testing in evaluation of ischemic heart disease in women.
- Conditions
- Angina Pectoris, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00000554
- Testing
- Angiography, MRI, Dobutamine-Stress Echocardiography, PET,, Myocardial Contrast Echo, Coronary Flow and Vasomotor Testing
- Sponsor
- University of Pittsburgh
Angina (Stable), Percutaneous Coronary Intervention (PCI)
Advanced Invasive Diagnosis Strategy for Post-PCI Patients With Stable Coronary Syndromes Undergoing Coronary Angiography
AID Post-PCI Angina is as an observational, prospective, single-cohort, multicenter study designed to investigate the causes and origins of post-PCI angina by using the advance invasive diagnosis (AID) strategy combining with…
- Conditions
- Angina (Stable), Percutaneous Coronary Intervention (PCI), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Chronic Coronary Syndrome
- Trial name
- NCT07638137
- Testing
- An advanced invasive diagnosis (AID) strategy combining with angiography derived physiology (ADP)
- Where
- 5 sites in Spain
- Volunteers
- 246 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Coronary Disease, Hypercholesterolemia
The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoris
The purpose of this study is to compare the effects of pravastatin and rosuvastatin on coronary plaque characteristics in patients with stable angina pectoris.
- Trial name
- NCT01325818
- Testing
- pravastatin, rosuvastatin
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- Yokohama City University Medical Center
Coronary Artery Disease, Ischemic Heart Disease
Coronary and Structural Interventions Ulm - Coronary Chronic Total Occlusions
To evaluate the long-term results after recanalization of coronary chronic total occlusions.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Stable Angina
- Trial name
- CSI-Ulm-CTO (NCT02162082)
- Testing
- stent or scaffold
- Where
- Germany
- Volunteers
- 198 people
- Sponsor
- University of Ulm
Acute Coronary Syndrome, Unstable Angina
Acute Coronary Syndrome Sri Lanka Audit Project
ACSSLAP is the first island wide audit project in Sri Lanka on ACS.
- Conditions
- Acute Coronary Syndrome, Unstable Angina, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- ACSSLAP (NCT02893280)
- Testing
- aspirin, clopidogrel, statin, enoxaparin, streptokinase
- Where
- Sri Lanka
- Sponsor
- University of Colombo
Atherosclerosis
Search a Correlation Between Lp(a) Rate and TFPI Activity in Obese Patients With Chest Pain Like Angina
Atherosclerotic cardiovascular disease is a leading cause of mortality in our countries. Clinically, symptoms could be chest pain suggesting stable angina.
- Trial name
- NCT01290770
- Testing
- blood sample
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chest Pain, Coronary Artery Disease
A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (or ASGES) in Primary Care Settings
The PRESET Registry--A Registry to Evaluate Patterns of Care Associated With the Use of Corus CAD (Age/Sex/Gene Expression score - ASGES) in Real World Clinical Care Settings (PRESET)--was designed as an observational…
- Conditions
- Chest Pain, Coronary Artery Disease, Cardiovascular Diseases, Coronary Heart Disease
- Trial name
- PRESET (NCT01677156)
- Testing
- CORUS CAD (ASGES)
- Where
- 13 sites in United States
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- CardioDx
Chest Pain, Stable Angina
In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes?
A randomised controlled trial to compare two strategies for the investigation of coronary artery disease at the time of angiography.
- Conditions
- Chest Pain, Stable Angina, Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome
- Trial name
- RIPCORD 2 (NCT02892903)
- Testing
- Routine Measurement of FFR
- Where
- 17 sites in United Kingdom
- Volunteers
- 1,100 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Chronic Stable Angina
Novel Vitality Indices Derived From the Hexoskin in Patients Affected With Angina Undergoing Coronary Revascularization or Medical Therapy
The first and foremost manifestation of ischemic heart disease (IHD) is angina. At a global level, patients with chronic angina are at risk of poor vital status and deconditioning.
- Trial name
- NOVA-SKIN (NCT02591758)
- Testing
- Hexoskin Vest, Cardiac rehabilitation program, Anxiety assessment as determined by the GAD-7
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Montreal Heart Institute
Chest Pain, Coronary Artery Disease
PROMISE Substudy to Assess For Effective Dose of Radiation (PROMISE-SAFER) Specific Aim 3b
The purpose of this study is to compare different methods of collecting the amount of radiation exposure patients receive in a clinical study.
- Conditions
- Chest Pain, Coronary Artery Disease, Angina
- Trial name
- PROMISE-SAFER (NCT01890525)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kaiser Permanente
Cardiac Ischemia, Chest Pain
Myocardial Ischemia Detection for Early Identification of Patients With Ischemic Chest Pain
The purpose of this study is to evaluate whether new novel markers from the clinical electrocardiogram (EKG), which have been used as non-invasive measures of heart disease, can detect coronary artery disease in patients with…
- Conditions
- Cardiac Ischemia, Chest Pain, Shortness of Breath
- Trial name
- MID-EPIC (NCT02055443)
- Testing
- 12-lead holter monitor application
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Coronary Artery Disease, Coronary Arteriosclerosis
DNA Repair in Patients With Stable Angina.
Markers of DNA damage and repair are present in both atherosclerotic plaques and peripheral blood mononuclear cells of patients with coronary artery disease.
- Conditions
- Coronary Artery Disease, Coronary Arteriosclerosis, DNA Damage, DNA Repair Abnormality
- Trial name
- DECODE II (NCT04453267)
- Where
- United Kingdom
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Coronary Artery Disease
Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery Disease
Yearly, 180 000 patients in the Netherlands are referred to a cardiologist with symptoms suspected of coronary artery disease (CAD). To assess this, multiple diagnostic tests are available.
- Trial name
- iCORONARY (NCT04939207)
- Testing
- CT-FFR, Angiography-derived FFR, Angiography with invasive FFR-measurements
- Where
- 4 sites in Netherlands
- Volunteers
- 825 people
- Sponsor
- St. Antonius Hospital
Microvascular Angina
Microvascular Angina Intervention With Compound Danshen Dripping Pill (MAIDS)
Coronary microvascular disease (MVD) refers to exertional angina or myocardial ischemia caused by abnormal structure and/or function of precoronary arterioles and arterioles under the action of various pathogenic factors.
- Trial name
- MAIDS (NCT06092736)
- Testing
- Compound Danshen Dropping Pills
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University
Coronary Artery Disease, Myocardial Ischemia
Safety and Efficacy Study of the Amaranth Medical FORTITUDE Bioresorbable Drug-Eluting Coronary Stent
The purpose of this study is to evaluate the safety and performance of a new coronary artery stent for treating blockages in the arteries supplying blood to the heart muscle.
- Trial name
- RENASCENT (NCT02255864)
- Testing
- AmM FORTITUDE Bioresorbable Drug-Eluting Coronary Scaffold
- Where
- 5 sites in Italy
- Volunteers
- 21 people
- Sponsor
- Amaranth Medical Inc.