Clinical trials: Anginal Pain
Coronary Disease, Angina, Stable
Registry of RESOLUTE-ONYX™ Zotarolimus-eluting Stent Utilization in Percutaneous Small Vessel Coronary Interventionism.
DESIGN: Prospective, single-arm, multicenter, observational, prospective registry of the use of the RESOLUTE-ONYX™ zotarolimus-eluting stent in percutaneous coronary intervention in small vessels.
- Conditions
- Coronary Disease, Angina, Stable, Ischemia, Acute Coronary Syndrome
- Trial name
- Disco-9 (NCT04785846)
- Testing
- Percutaneous Coronary Intervention
- Where
- 15 sites in Spain
- Volunteers
- 307 people
- Sponsor
- Fundación Investigación Sanitaria en León
Stable Coronary Artery Disease CAD
Angina Prevalence and Provider Evaluation of Angina Relief
The purpose of this study is describe the frequency of chest pain and how chest pain impacts patients' quality of life in the outpatients with chronic coronary artery disease in contemporary cardiology practice settings.
- Trial name
- APPEAR (NCT01705054)
- Where
- United States
- Volunteers
- 1,246 people
- Sponsor
- Saint Luke's Health System
Chronic Stable Angina
Yinxingmihuan Oral Solution in Treatment of Chest Pain After PCI
A prospective, multi-center, double-blind, randomized, placebo-controlled trial is conducted to evaluate the efficacy and safety of Yinxingmihuan oral solution in the treatment of chest pain after percutaneous coronary…
- Trial name
- NCT06224582
- Testing
- Yinxingmihuan oral solution
- Where
- China
- Volunteers
- 320 people
- Sponsor
- China National Center for Cardiovascular Diseases
Essential Hypertension, Chronic Stable Angina
Observational Study to Evaluate the Safety of DILATREND SR Cap. in Korean Patients With Essential Hypertension, Chronic Stable Angina and Congestive Heart Failure
The purpose of this study is to Evaluate the Safety of DILATREND SR Cap. in Korean Patients with Essential hypertension, Chronic stable angina and Congestive heart failure for 52 weeks.
- Conditions
- Essential Hypertension, Chronic Stable Angina, Congestive Heart Failure
- Trial name
- DELIGHT (NCT03063697)
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Angina
Safety Study of Transmyocardial Revascularization (TMR) With Bone Marrow Aspirate (BMAC) for Angina Reduction
The purpose of this study is to determine the safety of injecting autologous bone marrow concentrate with laser transmyocardial revascularization (TMR) for treatment of angina which cannot be treated by direct coronary…
- Trial name
- PHOENIX (NCT01285297)
- Testing
- Bone Marrow Aspirate Concentrate
- Where
- 2 sites in Russia, Spain
- Volunteers
- 7 people
- Sponsor
- Cardiogenesis Corporation, a wholly-owned subsidiary of CryoLife, Inc.
Coronary Disease, Angina, Unstable
Abciximab, Clopidogrel and Percutaneous Coronary Intervention in Acute Coronary Syndrome (ISAR-REACT-2)
The purpose of this study is to determine whether there is any additional benefit from abciximab administration during percutaneous coronary intervention in patients presenting with acute coronary syndromes after pre-treatment…
- Trial name
- NCT00133003
- Testing
- Abciximab
- Where
- 5 sites in Brazil, Germany and 1 more
- Volunteers
- 2,022 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Angina
Ranolazine Among Unrevascularized Chronic Stable Angina Patients
This is a prospective, double-blind, placebo-controlled, randomized, single-center (North Florida- South Georgia VA Medical Center) study.
- Trial name
- IMWELL (NCT02265796)
- Testing
- Ranolazine, Sugar pill
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- North Florida Foundation for Research and Education
Ischaemic Heart Diseases, Stenosis
BBC ONE - British Bifurcation Coronary Study
The study aims to assess whether a SIMPLE or a COMPLEX strategy is best for the treatment of coronary bifurcation stenoses.
- Conditions
- Ischaemic Heart Diseases, Stenosis, Angina
- Trial name
- BBC ONE (NCT00351260)
- Testing
- Coronary Angioplasty
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Royal Sussex County Hospital
Heart Diseases, Ischemic, Coronary Artery Disease
Power Walking in Cardiac Patients Who Underwent Post-coronary Angioplasty
The risk and prevalence of cardiovascular disease in United Arab Emirates (UAE) is high with ischemic heart disease ranks first in terms of major cause of mortality.
- Conditions
- Heart Diseases, Ischemic, Coronary Artery Disease, Coronary Arteriosclerosis, Coronary Syndrome
- Trial name
- PowerWalk (NCT04610060)
- Testing
- Power walking, Standardised outpatient cardiac rehabilitation
- Where
- United Arab Emirates
- Volunteers
- 24 people
- Sponsor
- Gulf Medical University
Angina, Stable
Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina
Compared with placebo, assess of the efficacy and safety of Guanxin Shutong capsule to treat chronic stable angina (syndrome of blood stasis resistance), and the result will be used for the basis of later Ⅳ clinical trial.
- Trial name
- NCT02280850
- Testing
- Guanxin Shutong Capsule, nitroglycerine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shaanxi Buchang Pharmaceutical Co., Ltd
Coronary Artery Disease, Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter to Treat Subjects Who Have Coronary Artery Disease (CAD) Involving In-Stent Restenosis (ISR) or an Unstented Lesion in a Small Coronary Vessel (DNSV).
The goal of this clinical trial is to learn if the SiroMax™ drug-coated balloon catheter is safe and works to treat stenotic coronary lesions in adults.
- Conditions
- Coronary Artery Disease, Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), In-Stent Restenosis or De Novo Coronary Artery Lesions, In-Stent Stenosis (Restenosis) of Coronary Artery Stent
- Trial name
- SMART-I (NCT07811024)
- Testing
- Sirolimus-coated balloon catheter
- Where
- 2 sites in Uzbekistan
- Volunteers
- 60 people
- Sponsor
- Tonic Medical, Inc.
Hypertension, Chronic Stable Angina
Bioequivalency Study of Amlodipine Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Amlodipine Besylate tablets, 10 mg, to Norvasc® Tablets, 10 mg (Pfizer) under fasting conditions using a single-dose, randomized, 2-treatment, 2-period…
- Conditions
- Hypertension, Chronic Stable Angina, Vasospastic Angina
- Trial name
- NCT00602017
- Testing
- Amlodipine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Major Coronary Event, Cerebrovascular Accident
CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events
A study to assess the efficacy of once daily atorvastatin 10 mg versus placebo on cardiovascular endpoints in patients with non-insulin-dependent diabetes mellitus (NIDDM) who have a history of either hypertension, retinopathy…
- Conditions
- Major Coronary Event, Cerebrovascular Accident, Coronary Artery Bypass Graft, Angina, Unstable
- Trial name
- CARDS (NCT00327418)
- Testing
- Atorvastatin
- Where
- 135 sites in United Kingdom
- Volunteers
- 2,800 people
- Sponsor
- Pfizer
Angina, Stable, Angina Pectoris, Variant
Coronary Microvascular Function and CT Coronary Angiography (CorCTCA)
Angina in patients without obstructive coronary artery disease (CAD) is a clinical conundrum and patient management is heterogeneous. Hypothesis: Abnormal coronary function is common and clinically relevant in this population.
- Conditions
- Angina, Stable, Angina Pectoris, Variant, Microvascular Angina
- Trial name
- CorCTCA (NCT03477890)
- Testing
- Stratified medicine involving a diagnostic intervention
- Where
- 3 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- NHS National Waiting Times Centre Board
Coronary Artery Disease, Chest Pain
Artificial Intelligence Stress Echo (FINESSE) Project
The goal of this observational study is to learn whether combining stress echocardiography (stress echo) results with routine clinical information can better predict important heart outcomes in adults (18+) with chest pain who…
- Conditions
- Coronary Artery Disease, Chest Pain, Myocardial Ischemia, Angina Pectoris
- Trial name
- FINESSE (NCT07432620)
- Testing
- Dobutamine Stress Echocardiography
- Where
- United Kingdom
- Volunteers
- 2,281 people
- Sponsor
- Milton Keynes University Hospital NHS Foundation Trust
Angina, Stable, Coronary Vasospasm
CORonary MICrovascular Angina (CorMicA)
Angina is form of chest pain that is due to a lack of blood to the heart muscle. Angina is commonly triggered by stress and exertion, and is a common health problem worldwide.
- Conditions
- Angina, Stable, Coronary Vasospasm, Coronary Circulation, Coronary Syndrome
- Trial name
- CorMicA (NCT03193294)
- Testing
- Stratified medicine involving a diagnostic intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 151 people
- Sponsor
- NHS National Waiting Times Centre Board
Physicians, Awareness
Physicians' Awareness of ECG Abnormalities Linked to Acute Ischemic Chest Pain
This study aims to investigate physicians' awareness regarding patients presenting with potential acute ischemic chest pain. It focuses on various electrocardiogram (ECG) patterns requiring prompt catheter lab activation for…
- Conditions
- Physicians, Awareness, ECG Abnormalities, Acute Ischemic Chest Pain
- Trial name
- NCT06836466
- Testing
- Google Form-based questionnaire
- Where
- Egypt
- Volunteers
- 640 people
- Sponsor
- Tanta University
Acute Coronary Syndromes
Finding Acute Coronary Syndromes (ACS) With Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms
Study Objectives The following items will be prospectively assessed. Primary Endpoints 1. For patients presenting with clinical suspicion of Acute Coronary Syndromes (ACS), high sensitivity-cardiac Troponin I (hs-cTnI) provides…
- Trial name
- FAST-TRAC (NCT00880802)
- Where
- 16 sites in United States, Greece and 2 more
- Volunteers
- 1,500 people
- Sponsor
- Nanosphere, Inc.
Coronary Atherosclerosis, Coronary Artery Disease
Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging
In a prospective international multicenter observational study, 1080 stable chest pain patients (REALITY Advanced registry of CCTA patients) with the suspected chronic coronary syndrome will be enrolled.
- Conditions
- Coronary Atherosclerosis, Coronary Artery Disease, Contrast-induced Nephropathy, Cerebrovascular Disease
- Trial name
- REALITY (NCT02440646)
- Testing
- Coronary computed tomography angiography, Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 4 sites in Estonia, Netherlands and 1 more
- Volunteers
- 1,080 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Acute Myocardial Infarction (AMI), Acute Coronary Syndrome (ACS)
Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction by Biomarkers
Oxygen treatment is widely used in acutely ill patients, both pre-hospital and in hospital. The indication for oxygen is sometimes unquestionable, such as in many hypoxic patients, but in other situations its use is more of a…
- Conditions
- Acute Myocardial Infarction (AMI), Acute Coronary Syndrome (ACS), ST Elevation (STEMI) Myocardial Infarction, Ischemic Reperfusion Injury
- Trial name
- DETO2X-bio (NCT02290080)
- Testing
- Oxygen
- Where
- 2 sites in Sweden
- Volunteers
- 175 people
- Sponsor
- Karolinska Institutet
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