Clinical trials: Anginal Pain
Angina Pectoris, Arteriosclerosis
Dan-NICAD - Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease
1. The primary purpose of this study is to determine the diagnostic accuracy of the CADscore System, a new danish technology that records sounds from turbulence of bloodflow in the coronary vessels. And secondary: 1.
- Conditions
- Angina Pectoris, Arteriosclerosis, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- NCT02264717
- Testing
- SPECT, Cardiac MRI
- Where
- 3 sites in Denmark
- Volunteers
- 1,676 people
- Sponsor
- University of Aarhus
Stable Angina, Unstable Angina
Safety and Effectiveness Evaluation of COBRA PzF Coronary Stent System: A Post Marketing Observational Registry
A multi-center, prospective, consecutive enrolled, observational registry. The population being studied includes all patients undergoing treatment of "de novo" lesions in native coronary vessels, saphenous vein graft and/or…
- Conditions
- Stable Angina, Unstable Angina, ACS - Acute Coronary Syndrome, STEMI
- Trial name
- eCOBRA (NCT03103620)
- Testing
- COBRA PzF Coronary Stent System
- Where
- 18 sites in France
- Volunteers
- 1,027 people
- Sponsor
- CeloNova BioSciences, Inc.
Major Cardiovascular Event, Established Atherosclerotic Cardiovascular Disease
A Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascular Events in Chinese Participants With Atherosclerotic Cardiovascular Disease
The primary objective of the study is to evaluate real-world effectiveness of treatment with Repatha® in combination with SOC, compared with SOC alone, on the risk for cardiovascular (CV) death, myocardial infarction (MI)…
- Trial name
- NCT06295679
- Where
- 90 sites in China
- Volunteers
- 7,000 people
- Sponsor
- Amgen
Coronary Artery Disease, Stable Angina Pectoris
A Comparative Evaluation of the Extent of Neointima Formation at 1 Month and 2 Months After Implantation Using OCT
The objective of this study is a comparative evaluation of BuMA Supreme™ stent and of Xience V/Prime stent in terms of the extent of neointima formation at 1 or 2 months after implanting in relatively high bleeding risk patients…
- Conditions
- Coronary Artery Disease, Stable Angina Pectoris, Unstable Angina Pectoris
- Trial name
- NCT02747329
- Testing
- BuMA Supreme™ stent, Xience V/Prime stent
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Sino Medical Sciences Technology Inc.
Angina Pectoris, Coronary Artery Disease
Utility of a Molecular Personalized Coronary Gene Expression Test (Corus CAD or ASGES) on Cardiology Practice Pattern
To investigate whether the use of Corus CAD (Age/Sex/Gene Expression score - ASGES) blood assay changes the diagnostic testing pattern in patients referred to a cardiologist for the evaluation of chest pain or anginal equivalent…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Chest Pain, Cardiovascular Diseases
- Trial name
- IMPACT-CARD (NCT01251302)
- Testing
- Corus CAD (ASGES)
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- CardioDx
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Hybrid Exercise Program for Heart Disease: Effect on Health and Quality of Life
Cardiac rehabilitation (CR) participation remains suboptimal, partly due to logistical challenges and limited access to center-based programs.
- Trial name
- NCT07130045
- Testing
- Hybrid Endurance Strength Training, Usual Care
- Where
- Malaysia
- Volunteers
- 84 people
- Sponsor
- University of Malaya
Stable Chronic Angina
Impact of Stent Length on Short Term Outcomes in Patients With Stable Coronary Disease Undergoing PCI
Impact of stent length on short term outcomes in patients with stable coronary artery disease undergoing PCI
- Trial name
- NCT03911895
- Testing
- Stent more than 26 mn length, Stent equal to or less than26 mn length
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Coronary Heart Disease, Stable Angina
Efficacy and Safety of Xueshuanxinmaining Tablet for the Treatment of Stable Angina Pectoris
This study is a randomized, double-blind, placebo-controlled, parallel clinical trial in Chinese population with stable angina pectoris.
- Trial name
- NCT04270279
- Testing
- Xueshuanxinmaining tablet, Nitroglycerin tablets
- Volunteers
- 120 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Angina Pectoris
Treatment of Reperfusion Event by Vitamin C Infusion
Primary Hypothesis: Prophylactic Vitamin C Intravenous Infusion at the time of percutaneous coronary intervention (PCI) would limit the size of the infarct, assessed by measurements of cardiac biomarkers, during acute myocardial…
- Trial name
- TREVI (NCT01090895)
- Testing
- Vitamin C
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Roma La Sapienza
Ischaemic Heart Disease, Coronary Heart Disease
Liraglutide to Improve corONary Haemodynamics During Exercise streSS
A single-centre double-blind placebo-controlled crossover randomised controlled trial to determine the physiological basis of glucagon-like peptide-1 receptor activation on exercise haemodynamics, as manifest through specific…
- Conditions
- Ischaemic Heart Disease, Coronary Heart Disease, Chronic Stable Angina
- Trial name
- LIONESS (NCT02315001)
- Testing
- Liraglutide
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- King's College London
Stable Angina, Silent Myocardial Ischemia
Efficacy and Safety of New Generation Drug Eluting Stents Associated With an Ultra Short Duration of Dual Antiplatelet Therapy. Design of the Short Duration of Dual antiplatElet Therapy With SyNergy II Stent in Patients Older Than 75 Years Undergoing Percutaneous Coronary Revascularization.
The main objective of the SENIOR study is to establish the efficacy and safety of the everolimus eluting stent with a biodegradable abluminal polymer (SYNERGY II) associated with a short dual antiplatelet therapy (DAPT) in…
- Conditions
- Stable Angina, Silent Myocardial Ischemia, Acute Coronary Syndrome
- Trial name
- SENIOR (NCT02099617)
- Testing
- Percutaneous Coronary Intervention (PCI) with short DAPT duration with Synergy II stent, Percutaneous Coronary Intervention (PCI) with short DAPT duration with Omega stent, Percutaneous Coronary Intervention (PCI) with short DAPT duration with Rebel stent
- Where
- 44 sites in Belgium, Finland and 7 more
- Volunteers
- 1,200 people
- Sponsor
- Ceric Sàrl
Coronary Artery Disease, Angina Pectoris
DUrable Polymer-based STent CHallenge of Promus ElemEnt Versus ReSolute Integrity
Rationale: The introduction of drug-eluting stents (DES) in the treatment of coronary artery disease has led to a significant reduction in morbidity but there are further demands on DES performance.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Unstable Angina Pectoris, Acute Coronary Syndrome
- Trial name
- DUTCHPEERS (NCT02175706)
- Testing
- Resolute Integrity®, Promus Element®
- Where
- 4 sites in Netherlands
- Volunteers
- 1,811 people
- Sponsor
- Thorax Centrum Twente
Angina Pectoris
Vein vs Arterial Grafts for Coronary Artery Bypass Grafting Surgery
The investigators have developed a novel technique for saphenous vein graft harvesting for coronary artery bypass grafting (CABG) where the graft is harvested with a pedicle of surrounding tissue.
- Trial name
- NCT02158455
- Testing
- NT SVG grafts
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Region Örebro County
Chronic Total Occlusion of Coronary Artery, Chronic Angina
VasoStar Vibrational Guidewire System to Facilitate Crossing Coronary Artery Chronic Total Occlusions
The goal of this project is to provide an improvement in wire performance to expedite crossing difficult lesions in the coronary vasculature.
- Trial name
- VST100 (NCT06193954)
- Testing
- VasoStar guidewire system
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- VasoStar, LLC
Factor XIII Deficiency, ST-Elevation Myocardial Infarction
Factor XIII and Other Biomarkers in ST Segment Elevation Myocardial Infarction
In medical practice, a combination of clinical exam, electrocardiograms, circulating biomarkers, and imaging is used to gain insights on the prognosis after myocardial infarction.
- Conditions
- Factor XIII Deficiency, ST-Elevation Myocardial Infarction, Myocardial Haemorrhage, Coronary Microvascular Disease
- Trial name
- eXIST (NCT03523624)
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Padova
Coronary Heart Disease, Stable Angina Pectoris
Heterogeneity of Neointimal Healing Following Biodegradable-polymer Drug-Eluting Coronary Stent Implantation
The objective of this study is a comparative evaluation of Orsiro stent and of Resolute Integrity stent in terms of the extent of neointima formation at 4 months after implantation using optical coherence tomography (OCT).
- Conditions
- Coronary Heart Disease, Stable Angina Pectoris, Silent Myocardial Ischemia
- Trial name
- Healing (NCT04465669)
- Testing
- Orsiro stents, Resolute Integrity® stents
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Coronary Microvascular Disease
Clinical Evaluation of Aromatic Wentong in the Treatment of Coronary Microvascular Disease
Coronary Microvascular Disease (CMD) is a condition where patients experience chest pain (angina) even though their coronary arteries appear normal on angiography.
- Trial name
- NCT06901570
- Testing
- Kuangxiong Aerosol
- Where
- China
- Volunteers
- 528 people
- Sponsor
- China-Japan Friendship Hospital
Angina With No Obstructive Coronary Artery Disease, ANOCA
Coronary Sinus Reducer in Patients With Angina With no Obstructive Coronary Disease
Even half of patients with angina undergoing invasive coronary angiography presents without any significant epicardial stenosis.
- Conditions
- Angina With No Obstructive Coronary Artery Disease, ANOCA, Coronary Sinus Reducer
- Trial name
- REDUCE-ANOCA (NCT07010029)
- Testing
- Coronary Sinus Reducer
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Coronary Syndrome
Comparison of Conventional and Non-Conventional CRF and Their Association With Acute Coronary Syndrome
This research aims to compare conventional and non-conventional cardiovascular risk factors and their association with Acute Coronary Syndrome (ACS).
- Trial name
- NCT07049302
- Testing
- Conventional Risk Factor Assessment, Non-Conventional Risk Factor
- Where
- Pakistan
- Volunteers
- 222 people
- Sponsor
- Superior University
Pseudo Angina, Myofascial Pain Syndromes
Treatment of Pectoralis Trigger Points in Patients With Pseudo Angina
Pseudo-angina is a musculoskeletal condition characterized by chest pain that resembles angina but occurs due to non-cardiac causes, particularly myofascial trigger points in the chest wall muscles.
- Conditions
- Pseudo Angina, Myofascial Pain Syndromes, Pectoralis Muscles, Musculoskeletal Chest Pain
- Trial name
- GT-LIC (NCT07728357)
- Testing
- Graston Technique, Local Ischemic Compression
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Faisalabad
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.