Clinical trials: Angiopathy, Peripheral
Phlebitis
In-line Filtration Reduces Postoperative Phlebitis.
The aim of this study is to demonstrate the efficacy of in-line filtration in reducing the incidence of postoperative phlebitis associated with peripheral short-term vascular access.
- Trial name
- NCT03193827
- Testing
- In-line filtration, Standard treatment
- Volunteers
- 268 people
- Sponsor
- Careggi Hospital
Peripheral Vascular Diseases, Percutaneous Intervention Via Femoral Artery
Angio-seal VIP Versus Perclose ProGlide for Closure of the Femoral Artery in Peripheral Vascular Disease
This study is designed to evaluate the efficacy (device deployment characteristics and performance) and safety (adverse access site related events) of Perclose ProGlide (Abbott Vascular Devices) for femoral access site closure in…
- Trial name
- NCT05334095
- Testing
- Perclose ProGlide, Angio-seal VIP
- Where
- China
- Volunteers
- 1,062 people
- Sponsor
- Xiongjing Jiang
Peripheral Artery Disease
AMS INSIGHT 1 Study - Bioabsorbable Metal Stent Investigation in Chronic Limb Ischemia Treatment
Prospective, multicenter, randomized clinical trial, Follow-up at 1-, 6- and 12 months This clinical investigation is first of all designed to demonstrate the safety and effectiveness of the MAGIC EXPLORER stent system.
- Trial name
- AMS-INSIGHT1 (NCT00572494)
- Testing
- MAGIC EXPLORER (Biotronik AG), PLEON EXPLORER (Biotronik AG)
- Where
- 12 sites in Austria, Belgium and 2 more
- Volunteers
- 117 people
- Sponsor
- Flanders Medical Research Program
Critical Limb Ischemia
The Use of FlowMet-R Technology to Predict Wound Healing in CLI Patients in a Wound Care Center Setting
Single-institution, prospective nonrandomized pilot study of critical limb ischemia patients with planned lower extremity revascularization will undergo Flowmet-D measurements in a wound care center setting to determine threshold…
- Trial name
- NCT05455554
- Testing
- Flowmet-D, ABI
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Peripheral Arterial Disease
Mini S Feasibility Study With Shockwave Medical Mini S Peripheral IVL System
Prospective, multi-center, single-arm feasibility study to assess the safety and performance of the Shockwave Medical Mini S Peripheral IVL System for the treatment of heavily calcified, stenotic peripheral arteries.
- Trial name
- NCT05058456
- Testing
- Shockwave Medical Mini S Peripheral IVL Catheter
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 35 people
- Sponsor
- Shockwave Medical, Inc.
Primary Erythromelalgia, Inherited Erythromelalgia
Study of XPF-001 in the Treatment of Pain From Primary/Inherited Erythromelalgia (IEM)
The purpose of this study is to determine whether XPF-001 is safe and effective in the treatment of pain caused by Inherited Erythromelalgia (IEM).
- Trial name
- NCT01090622
- Testing
- XPF-001
- Where
- Netherlands
- Volunteers
- 4 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Peripheral Artery Disease
IV-X Medical First-in-Human Peripheral Intravascular Lithotripsy Study for PAD
To evaluate the safety and performance of the IV-X Medical Intravascular Lithotripsy (IVL) System in adults in order to demonstrate the ability of the IV-X Medical IVL System to safely and effectively deliver IVL treatment…
- Trial name
- HELIX-PAD-FIH (NCT07747883)
- Testing
- IV-X Medical IVL System
- Where
- Paraguay
- Volunteers
- 25 people
- Sponsor
- IVX Medical
Arteriosclerosis, Peripheral Artery Disease
Durg Coated Balloon Angioplasty in Infrapopliteal Lesions
This study is a multicenter observational study designed to evaluate the the effectiveness and safety of drug-coated balloon (DCB) angioplasty for below the knee arterial lesions in patients critical with Limb Threatening…
- Conditions
- Arteriosclerosis, Peripheral Artery Disease, Chronic Limb Threatening Ischemia
- Trial name
- Act (NCT05620095)
- Testing
- drug-coated balloon
- Where
- 10 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology
Peripheral Arterial Disease
Establishing the Microcirculatory Effects of Ticagrelor on Tissue Perfusion in Critical Limb Ischemia
This is a single center, prospective, randomized, unblinded, open-label, active controlled pilot study to evaluate the efficacy and safety of ticagrelor plus aspirin versus clopidogrel plus aspirin in patients with Rutherford…
- Trial name
- NCT02230527
- Testing
- Ticagrelor, Clopidogrel
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- The Cleveland Clinic
Peripheral Arterial Disease
Investigational Study of SWM-831 to Treat Moderate and Severely Calcified Femoropopliteal Arteries
Disrupt PAD Japan is a prospective, multi-center, single-arm study of SWM-831 to treat moderate and severely calcified femoropopliteal arteries, prior to DCB or stenting.
- Trial name
- NCT06938854
- Testing
- Peripheral Intravascular Lithotripsy (IVL)
- Where
- 10 sites in Japan
- Volunteers
- 81 people
- Sponsor
- Shockwave Medical, Inc.
Cardiovascular Disease, Peripheral Artery Disease
Platelet Activity in Vascular Surgery and Cardiovascular Events
Pathological and clinical studies have consistently demonstrated that abnormalities in thrombosis and hemostasis play a major role in the pathogenesis of atherosclerosis and atherothrombosis.
- Conditions
- Cardiovascular Disease, Peripheral Artery Disease, Critical Limb Ischemia
- Trial name
- PACE (NCT02106429)
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- NYU Langone Health
Complications
Standard Length Catheters vs Long Catheters in Peripheral Vein Cannulation.
The Long and Short is a prospective, randomized, controlled, open label trial to test the complications of different device for peripheral vein cannulation, standard length (about 5 cm in length) and long catheter (about 12 cm in…
- Trial name
- Long&short (NCT01917253)
- Testing
- Standard Device for peripheral vein cannulation, Long Catheters for peripheral vein cannulation
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- ASL TO2 Torino
Raynaud's Disease
Dose Response Study of a Topical Formulation of Nitroglycerin for the Treatment of Raynaud's Phenomenon
The purpose of this clinical study is to determine the response to two different dosage strengths of a topical nitroglycerin gel in patients with Raynaud's Phenomenon.
- Trial name
- NCT00480753
- Testing
- Nitroglycerin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- MediQuest Therapeutics
Hypercholesterolemia
Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia
Study of efficacy, safety, tolerability and quality of life of inclisiran (KJX839) vs placebo, on top of ongoing individually optimized lipid-lowering therapy, in participants with hypercholesterolemia
- Trial name
- V-DIFFERENCE (NCT05192941)
- Testing
- Inclisiran Sodium
- Where
- 136 sites in Bulgaria, Czechia and 6 more
- Volunteers
- 1,770 people
- Sponsor
- Novartis Pharmaceuticals
Ischemia, Peripheral Arterial Disease
Cook Micronized Small Intestinal Submucosa (SIS) for Critical Limb Ischemia
This study is intended to collect safety and effectiveness data on the Cook Micronized Small Intestinal Submucosa (SIS)
- Conditions
- Ischemia, Peripheral Arterial Disease, Peripheral Vascular Diseases
- Trial name
- NCT02044666
- Testing
- Micronized Small Intestinal Submucosa (SIS)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Cook Group Incorporated
Peripheral Arterial Disease
MIMICS-3D-USA Registry Study
The MIMICS-3D-USA Study is a prospective, multicentre, observational study (non-investigational) of the BioMimics 3D Vascular Stent System that evaluates evaluate safety, effectiveness and device performance within a real-world…
- Trial name
- NCT04640597
- Testing
- BioMimics 3D Vascular Stent System
- Where
- 27 sites in United States
- Volunteers
- 500 people
- Sponsor
- Veryan Medical Ltd.
Peripheral Vascular Disease
VQI DELTA Paclitaxel Device Safety Analysis
The VQI-DELTA Paclitaxel Device Safety Analysis seeks to assess the comparative safety of paclitaxel coated balloons and stents in the treatment of peripheral artery disease (PAD) through analysis of the VQI Peripheral Vascular…
- Trial name
- VQI-PTX (NCT04110288)
- Testing
- Paclitaxel, Non-drug coated Device Treatment
- Where
- United States
- Volunteers
- 219,483 people
- Sponsor
- Lahey Clinic
Peripheral Vascular Disease, Cardiovascular Disease
RISE: A Clinical Evaluation of the StarClose™ Vascular Closure System
To evaluate early ambulation in patients who receive the StarClose™ VCS post-percutaneous diagnostic procedure.
- Trial name
- NCT00736086
- Testing
- Vessel Closure (StarClose™)
- Where
- 11 sites in United States
- Volunteers
- 165 people
- Sponsor
- Abbott Medical Devices
Critical Limb Ischemia
ACP-01 in Patients With Critical Limb Ischemia
The primary objective of this study is to determine the efficacy and safety of intramuscular injection of ACP-01, comprised of blood-derived autologous ACPs, in subjects with critical limb ischemia who are receiving standard of…
- Trial name
- NCT02551679
- Testing
- ACP-01
- Where
- 19 sites in United States, Canada
- Volunteers
- 67 people
- Sponsor
- Hemostemix
Influence of PRU Values on Primary Outcome
High on Treatment Platelet Reactivity Following Peripheral Endovascular Procedures
Antiplatelet therapy with clopidogrel is recommended following peripheral endovascular procedures. The clinical significance of an inadequate response to clopidogrel following percutaneous coronary interventions has been recently…
- Trial name
- PRECLOP (NCT01744613)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Patras