Clinical trials: Angioplasty Patients
Cardiovascular Disease, Myocardial Infarction
A Prospective, Randomized Trial of BVS Veruss EES in Patients Undergoing Coronary Stenting for Myocardial Infarction
The aim of the current study is to test the clinical performance of the everolimus-eluting BVS compared with that of the durable polymer everolimus-eluting stent (EES) in patients undergoing PCI in the setting of acute MI.
- Conditions
- Cardiovascular Disease, Myocardial Infarction, Thrombus, Primary Angioplasty
- Trial name
- ISAR-Absorb MI (NCT01942070)
- Testing
- Bioresorbable vascular scaffold, Durable polymer everolimus-eluting metallic stent
- Where
- 2 sites in Germany
- Volunteers
- 262 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Angioplasty Patients
A Randomized Trial: Changing Behavior in Post-Angioplasty Patients
The long-term objective of this study is to determine whether a positive affect and self-affirmation condition added to an empirically demonstrated approach for motivating behavior change is more effective than a standard…
- Trial name
- NCT00248846
- Testing
- Intervention Group
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Thromboembolic Pulmonary Hypertension
N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension.
This study will evaluate the use of N-acetyl cysteine in post-reperfusion pulmonary injury in patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary balloon angioplasty and pulmonary endarterectomy.
- Trial name
- NAC-PostRep (NCT04081012)
- Testing
- N-acetyl cysteine
- Where
- Mexico
- Volunteers
- 34 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
ST Elevation Myocardial Infarction, STEMI
Rheolytic Thrombectomy in Patients With Acute STEMI and Large Thrombus Burden
Coronary obstruction by an occlusive thrombus complicating a ruptured or eroded atherosclerotic plaque is the most frequent pathologic substrate of acute myocardial infarction (AMI).
- Trial name
- Rheo-STEMI (NCT02604394)
- Testing
- Rheolytic Thrombectomy, Conventional PCI
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Magdi Yacoub Heart Foundation
Acute Coronary Syndrome, Type 2 Diabetes
A Phase 2 Study to Determine the Effects of BXT-51072 in Diabetic Patients Undergoing Angioplasty (PCI)
The purpose of this study is to determine the safety and feasibility of BXT-51072 as a cardioprotective agent in diabetics undergoing elective angioplasty / percutaneous intervention (PCI), a procedure to "open" coronary…
- Trial name
- NCT00320502
- Testing
- BXT-51072
- Where
- 4 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Synvista Therapeutics, Inc
Contrast-induced Nephropathy
Contrast Induced Nephropathy Among Vascular Patients Undergoing Lower Limb Angioplasty
Contrast induced nephropathy (CIN) is an iatrogenic renal injury following intravascular administration of radio-opaque contrast media (CM) in susceptible individuals.
- Trial name
- NCT04879186
- Testing
- Peripheral endovascular angioplasty
- Where
- Singapore
- Volunteers
- 1,500 people
- Sponsor
- Singapore General Hospital
Critical Limb Ischaemia, Claudication
Peripheral Vascular Disease and Nerve Stimulation
A study to see what effect the geko™ device has on blood flow in patients with lower limb vascular disease.
- Conditions
- Critical Limb Ischaemia, Claudication, Ulcers, Varicose Veins
- Trial name
- CCLINS (NCT01942941)
- Testing
- geko™ electrical stimulation
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
ST Elevation Myocardial Infarction
Minimal Invasive Procedure for Myocardial Infarction
In the setting of primary Percutaneous Coronary Intervention (PCI), the investigators hypothesize that a 24-48 hour delay strategy of stenting after successful thrombus aspiration and establishment of Thrombolysis In Myocardial…
- Trial name
- MIMI (NCT01360242)
- Testing
- MIMI procedure (two-step strategy), Immediate Stenting (one-step strategy)
- Where
- 24 sites in France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Acute Myocardial Infarction
The Melatonin Adjunct in the Acute myocaRdial Infarction Treated With Angioplasty
Background: Experimental studies have documented the beneficial effects of the endogenously produced antioxidant, melatonin, in reducing tissue damage and limiting cardiac pathophysiology in models of experimental…
- Trial name
- MARIA (NCT00640094)
- Testing
- melatonin
- Where
- 3 sites in Spain
- Volunteers
- 272 people
- Sponsor
- Alberto Domínguez Rodríguez
Atrial Fibrillation, Coronary Artery Disease
The Greek AntiPlatElet Atrial Fibrillation Registry.
Approximately 5% to 7% of patients undergoing percutaneous coronary intervention for the treatment of coronary artery disease, require chronic oral anticoagulation on top of aspirin and a P2Y12 receptor antagonist, mainly due to…
- Trial name
- GRAPE-AF (NCT03362788)
- Testing
- VKA, NOAC
- Where
- Greece
- Volunteers
- 654 people
- Sponsor
- Attikon Hospital
Contrast Induced Nephropathy, Acute Myocardial Infarction
Comparison Between Iso-Osmolar and Ipo-Osmolar Contrast Agents in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary Percutaneous Coronary Intervention (PCI)
The purpose of this study is to determine the incidence of contrast induced nephropathy and myocardial tissue reperfusion following iso-osmolar iodixanol or ipo-osmolar iopromide administration in patients with acute myocardial…
- Trial name
- CONTRAST-AMI (NCT00827788)
- Testing
- Iodixanol, Iopromide
- Where
- Italy
- Volunteers
- 432 people
- Sponsor
- Ospedale San Donato
Myocardial Infarction
Optimizing Infarct Size by Transforming Emergent Stenting Into an Elective Procedure Study
The goal of primary PCI is to restore anterograde myocardial flow. Stenting a largely thrombotic lesion may determine distal embolisation of thrombotic material therefore deteriorating myocardial perfusion.
- Trial name
- OPTIMASTRATEGY (NCT01462188)
- Testing
- Immediate stenting, Delayed stenting
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Marco Valgimigli
Chronic Thromboembolic Pulmonary Hypertension
Optimized Management After Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension
Balloon pulmonary angioplasty (BPA) is a new method of treatment for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) or persistent CTEPH after surgery.
- Trial name
- POpPART (NCT04777448)
- Testing
- telerehabilitation
- Volunteers
- 54 people
- Sponsor
- University Hospital, Grenoble
Coronary Artery Disease
SERIES III RUN-IN Clinical Trial: A Comparison of the Supralimus® Stent With the Xience V™ Stent
The objective of Series III Run-In Trial is to compare the performance and efficacy of the Supralimus® sirolimus-eluting stent with the Xience V™ everolimus-eluting stent with respect to in-stent luminal late loss at 9 months as…
- Trial name
- NCT00917163
- Testing
- Supralimus(R) Sirolimus-Eluting Coronary Stent System, Xience V™ Everolimus Eluting Coronary Stent
- Where
- 28 sites in Brazil, India and 1 more
- Volunteers
- 13 people
- Sponsor
- Sahajanand Medical Technologies Limited
Peripheral Artery Disease
Safety/Feasibility of Vonapanitase Following Angioplasty for Patients With Peripheral Artery Disease (PAD) Below the Knee (BTK)
The research study is designed to assess the technical feasibility and safety of a perivascular injection of vonapanitase delivered via micro-infusion catheter to the distal popliteal, tibial or peroneal arteries immediately…
- Trial name
- NCT02956993
- Testing
- vonapanitase
- Where
- 9 sites in United States
- Volunteers
- 29 people
- Sponsor
- Proteon Therapeutics
Acute Myocardial Infarction
GPIIbIIIa Inhibitors in the RESCUe and RESURCOR Networks at the Acute Myocardial Infarction
In patients with acute myocardial infarction who are managed in the prehospital setting, and who will treated with primary angioplasty, we evaluate the benefit of an early administration of tirofiban, a powerful GPIIbIIIa…
- Trial name
- AGIR2 (NCT00538317)
- Testing
- tirofiban
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Hospices Civils de Lyon
Coronary Artery Disease
Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease
The primary objective of the PRE-COMBAT trial is: To establish the safety and effectiveness of coronary stenting with the sirolimus-eluting balloon expandable stent (Cordis Johnson \& Johnson, Warren, New Jersey) compared with…
- Trial name
- PRECOMBAT (NCT00422968)
- Testing
- Percutaneous coronary intervention, coronary artery bypass graft
- Where
- 13 sites in South Korea
- Volunteers
- 1,454 people
- Sponsor
- Seung-Jung Park
Peripheral Vascular Disease, Peripheral Arterial Disease
EVERO Drug-coated Balloon (DCB) Randomized Trial
The primary objective of the study is to evaluate the long-term safety and effectiveness of the Advance Evero™ 18 Everolimus-coated Percutaneous Transluminal Angioplasty Balloon Catheter (hereafter referred to as the Evero…
- Trial name
- NCT07144150
- Testing
- Evero DCB, Paclitaxel DCB
- Where
- 12 sites in United States
- Volunteers
- 410 people
- Sponsor
- Cook Research Incorporated
Kidney Diseases, Urologic Diseases
Folic Acid for Prevention of Contrast Induced Nephropathy
The purpose of this study is to determine whether periprocedural administration of folic acid is effective in the prevention of contrast induced nephropathy in patients undergoing coronary CTA/angiography/angioplasty.
- Trial name
- FAPCIN (NCT02444013)
- Testing
- Folic acid
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Angioplasty, Cardiovascular Disease
XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS) China Single-Arm Study
Abbott Vascular (AV) obtained marketing approval for the XIENCE PRIME Everolimus Eluting Coronary Stent System (XIENCE PRIME EECSS) in China from the China Food and Drug Administration (CFDA) on August 10th, 2011.
- Conditions
- Angioplasty, Cardiovascular Disease, Coronary Artery Disease, Coronary Heart Disease
- Trial name
- XP China SAS (NCT01894152)
- Testing
- XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS)
- Where
- United States
- Volunteers
- 2,002 people
- Sponsor
- Abbott Medical Devices