Clinical trials: Ankle
Peripheral Artery Disease, Vascular Disease
Adenosine-induced Myocardial Blood Flow in Peripheral Artery Disease Patients
The purpose of the study is to assess the effect of blood flow to the heart when subjects are treated with ticagrelor (Brilinta) or clopidogrel (antiplatelet drugs that stop the blood from clumping together) in patients with…
- Conditions
- Peripheral Artery Disease, Vascular Disease, Arterial Occlusion Disease, Intermittent Claudication
- Trial name
- PAD (NCT02121288)
- Testing
- Ticagrelor, clopidogrel
- Sponsor
- AstraZeneca
Ankle Rheumatoid Arthritis, Arthritis of Ankle
Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US Only
The objectives of this study are to evaluate the performance and safety of the Vantage Total Ankle System. This study will follow subjects for a period of up to 10 years post-surgery.
- Conditions
- Ankle Rheumatoid Arthritis, Arthritis of Ankle, Failure, Prosthesis
- Trial name
- NCT05619588
- Where
- 2 sites in United States
- Volunteers
- 370 people
- Sponsor
- Exactech
Gait
Toe Walker Gait Trial
The purpose of this study is to examine the change in ankle plantar flexion while walking, following treatment with the Ankle Dorsiflexion Dynasplint (AFD) for children diagnosed as Toe Walkers.
- Trial name
- TW (NCT01208142)
- Testing
- standard of care treatment, Ankle Flexion Dynasplint
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dynasplint Systems, Inc.
Ankle Injuries, Foot Injury
Monster Screw System Post-Market Clinical Follow-Up Study
Post-market clinical follow-up study on the Monster Screw System
- Trial name
- NCT05190159
- Testing
- Monster Screw System
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Paragon 28
Lower Extremity Surgery, Bunion
Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries
This is a Phase 3, multicenter, randomized, double blinded, active controlled study in approximately 120 subjects undergoing lower extremity surgeries.
- Conditions
- Lower Extremity Surgery, Bunion, Metatarsophalangeal Fushion, Midfoot Fusion
- Trial name
- STRIDE (NCT04518462)
- Testing
- Exparel, Bupivacaine Hydrochloride
- Where
- 5 sites in United States
- Volunteers
- 121 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Ankle Arthritis, Foot Arthritis
The Use of a Dynamic Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis
The purpose of this study is to determine the clinical efficacy of a novel dynamic compression intramedullary nail for tibiotalocalcaneal (TTC) arthrodesis.
- Trial name
- NCT03686241
- Testing
- Tibiotalocalcaneal (TTC) arthrodesis, DynaNail
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- MedShape, Inc
Arthritis, Rheumatoid Arthritis
Wright Foot & Ankle Post-Market Observational Study
WRIGHT FOOT \& ANKLE POST-MARKET OBSERVATIONAL STUDY, Multi-Year, Multi-Site, Multi-Device, Post-Market Observational Study, 10 sites, a minimum of 40 patients per device
- Conditions
- Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury
- Trial name
- NCT04118894
- Testing
- Foot and Ankle Devices
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Ankle Injuries, Sprains and Strains
Impact of Hyperarch Fascia Training on Ankle Health and Exercise Performance
The purpose of this clinical trial is to evaluate whether the Hyperarch Fascia Training (HFT) program can reduce ankle pain and improve jump performance in active adults aged 20-45 with a history of ankle sprains.
- Conditions
- Ankle Injuries, Sprains and Strains, Joint Instability
- Trial name
- NCT06959472
- Testing
- Hyperarch Fascia Training
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Applied Science & Performance Institute
Genu Varum, Genu Valgum
Retrospective Evaluation of Guided Growth Plate System Plus's Safety and Clinical Performance for the Treatment of Lower Limbs Deformities.
Orthofix is conducting this retrospective Post-market clinical follow up (PMCF) study to assess the safety and clinical performance of the Guided Growth Plate System Plus (GGPSP) device, which is a new version of the Guided…
- Conditions
- Genu Varum, Genu Valgum, Joint Diseases, Knee Deformity
- Trial name
- NCT05241691
- Testing
- Guided Growth Plate System Plus
- Where
- Italy
- Volunteers
- 69 people
- Sponsor
- Orthofix s.r.l.
Osteoarthritis, Rheumatoid Arthritis
Ankle Joint Replacement Outcomes Study
This post market outcome study will look at the therapeutic results of the Salto Talaris Anatomic ankle prosthesis. The study population will consist of patients who will undergo an ankle arthroplasty procedure with a Salto…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Septic Arthritis
- Trial name
- NCT00503438
- Testing
- Salto Talaris Ankle
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Smith & Nephew, Inc.
Sprain of Ankle
Evaluation of the Effect of the Association of Proton Pump Inhibitor (PPIs) With Non-Steriodal Anti-Inflamatories (NSAIDs) in Work Leave Time.
Retrospective cohort study to evaluate the effect of the association of PPIs with NSAIDs in work leave time.
- Trial name
- NCT00717119
- Where
- Spain
- Volunteers
- 6,356 people
- Sponsor
- AstraZeneca
Ankle Sprain
HKT-500 in Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00680784
- Testing
- HKT-500 Ketoprofen Topical Patch
- Where
- 30 sites in United States
- Volunteers
- 260 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Lower Limb, Pareses
C-BRACE Versus SCO in Community Ambulators
The purpose of this multicentric study is to assess the impact of C-BRACE on mobility, endurance, confidence, participation, satisfaction, psychosocial adjustment and quality of life in community ambulators using a Stance Control…
- Trial name
- NCT05332509
- Testing
- C-BRACE, SCO
- Where
- 18 sites in France, Germany
- Volunteers
- 38 people
- Sponsor
- Otto Bock France SNC
Surgery
Inion OTPS Biodegradable Fixation System for the Ankle
The purpose of the investigation is to compare post-operative fracture and wound healing using Inion OTPS Biodegradable Fixation System implants versus Conventional metal implants.
- Trial name
- NCT00300989
- Testing
- Inion OTPS Biodegradable Fixation System
- Where
- Finland
- Volunteers
- 43 people
- Sponsor
- Inion Oy
Ankle Sprain
TRAUMED - a Clinical Trial in Acute Ankle Sprain
TRAUMED - a randomized clinical trial evaluating the efficacy and safety of Traumed® gel in patients with acute ankle sprain.
- Trial name
- TRAUMED (NCT06192420)
- Testing
- Traumeel®, Diclofenac sodium gel 1%
- Where
- Germany
- Volunteers
- 809 people
- Sponsor
- Biologische Heilmittel Heel GmbH
Arthritis, Rheumatoid
INFINITY™Total Ankle Replacement Follow-up
Study Title INFINITY™Total Ankle Replacement Follow-up (ITAR) Study Design Prospective, multi-site, multi-year post-market clinical follow-up study Study Group Primary/Unilateral and/or bilateral Total Ankle Arthroplasty subjects…
- Trial name
- ITAR (NCT03277989)
- Where
- 9 sites in United States
- Volunteers
- 155 people
- Sponsor
- Stryker Trauma and Extremities
Ankle Sprain
HKT-500 in the Treatment of Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00927641
- Testing
- Ketoprofen Patch
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Hypertension
A Study to Evaluate Methodologies for Measuring Swelling of the Leg and Ankle (MK-0000-106)(COMPLETED)
This study will evaluate methodologies for measuring pedal edema associated with calcium channel blockers in middle-aged and elderly subjects and patients with hypertension.
- Trial name
- NCT00789321
- Testing
- Comparator: amlodipine besylate
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Avascular Necrosis of the Talus
Patient Specific Talus Spacer Post Approval Study
Humanitarian Device Exemption Approved Patient Specific Talus Spacer Post Approval Study.
- Trial name
- NCT05364606
- Testing
- Patient Specific Talus Spacer
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Paragon 28
Ankle Sprains
MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains
A Randomized, Multi-Center, Double-Blind, Factorial, Comparator and Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle…
- Trial name
- NCT01198834
- Testing
- MRX-7EAT, Lidocaine, Etodolac
- Where
- 33 sites in United States
- Volunteers
- 600 people
- Sponsor
- MEDRx USA, Inc.