Clinical trials: Ankle
Ankle Osteoarthritis
Lateral Approach Versus Anterior Approach in Total Ankle Replacement
A minimum of 50 patients with ankle end-stage arthritis will be randomized in two parallel groups for surgery. One group will receive a total ankle replacement through an anterior approach and the other group a total ankle…
- Trial name
- NCT05562154
- Testing
- Total Ankle Replacement
- Where
- United States
- Sponsor
- John Femino
Patients Undergoing Ankle Surgery
Duration of Analgesia After Popliteal Fossa Nerve Blockade: Effects of Dexamethasone and Buprenorphine
Patients scheduled to go home after ankle surgery at HSS typically receive a sciatic nerve block in the popliteal fossa and oral analgesic tablets (such as Percocet).
- Trial name
- NCT01277159
- Testing
- A. Control Nerve Block. IV Dexamethasone (4 mg)., B. Nerve Block with Dexamethasone (4 mg). IV saline., C. Control Nerve Block. IV Dexamethasone (4 mg). IV Buprenorphine (0.3 mg)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Hospital for Special Surgery, New York
Neurological Disorder
Side Pole Static Ankle Foot Orthosis in Children With Neurological Disorders
Transverse-plane foot deformities are a frequently encountered issue in children with neurological disorders. They are the source of many symptoms, such as pain and walking difficulties, making their prevention very important.
- Trial name
- SPS-AFO (NCT03146598)
- Testing
- No intervention as it is a observational study
- Volunteers
- 100 people
- Sponsor
- BERTHILLIER Julien
Osteoarthritis, Hip, Osteoarthritis Thumb
Evaluate Clinical Benefit of Local Treatment With KD Intra-Articular® Gel in Patients With Osteoarthritis (NO-DOLOR2)
Prospective observational, national, multicentre, open study with a class III medical device with EC marking. Study to evaluate the clinical benefit of local treatment with KD intra-articular® gel in patients with osteoarthritis…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis Thumb, Osteoarthritis Ankle
- Trial name
- NO-DOLOR2 (NCT05275244)
- Testing
- KD Intra-Articular® gel
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- Procare Health Iberia S.L.
Chronic Ankle Instability
The Effectiveness of Unilateral and Bilateral Exercise Training in Patients With Lateral Ankle Instability
70% of the general population suffers ankle injuries at least once in their lifetime. The ankle lateral ligament injuries cause an average of 6.9 days of work loss, and it has been reported that the quality of life of these…
- Trial name
- NCT04360798
- Testing
- Unilateral Exercise Group, Bilateral Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Muscle Physiology
Whole Body Vibration Induced Muscle Activity and Effect of the Changes in Length of Soleus Muscle and Angle of Ankle
Previous studies reported that myoelectrical activity increased during whole body vibration (WBV). The investigators hypothesized that the change in soleus muscle length does not affect the whole body vibration induced soleus…
- Trial name
- WBVIMR-SL (NCT02468011)
- Testing
- vibration
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Acute Fracture Surgery, Alcohol Cessation Intervention
Alcohol Cessation Intervention in an Acute Surgical Setting
Hazardous alcohol intake is an independent risk factor for postoperative complications after major and minor operations, elective and emergency procedures for men and women.
- Conditions
- Acute Fracture Surgery, Alcohol Cessation Intervention, Postoperative Complications, Infection
- Trial name
- NCT00986791
- Testing
- GSP-A
- Where
- 3 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Bispebjerg Hospital
Ankle Sprain
Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain
To assess the efficacy of celecoxib loading dose of 400mg followed by 200 mg twice a day (BID) versus oral non-selective NSAIDs in acute pain due to ankle sprain.
- Trial name
- NCT00446797
- Testing
- Non-selective NSAIDS, Celecoxib
- Where
- 16 sites in Brazil, Costa Rica and 6 more
- Volunteers
- 278 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Ankle Fractures
Ankle Fracture vs Ankle Fracture-Dislocation
The purpose of this study is to compare outcomes of patients with an ankle fracture to those with ankle fracture-dislocations. We hypothesize that long-term clinical outcomes for patients sustaining ankle fracture dislocations…
- Trial name
- NCT02198768
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Stroke
Interactive Exoskeleton Robot for Walking
A new lower-limb training system is introduced to enhance the clinical service for post-stroke lower limb rehabilitation and to assist the establishment of public clinical trial in different settings and share experiences on the…
- Trial name
- NCT03184259
- Testing
- Robotic ankle system, Robotic knee system
- Where
- Hong Kong
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Ankle Injuries, Ankle Injuries and Disorders
The Effect of Taping on Plantar Pressure Distribution in Players With Chronic Ankle Instability
The goal of this study is to investigate whether there exists a difference in baropdometric readings of plantar pressure between individuals with chronic ankle instability and normal health individuals, in addition another goal…
- Conditions
- Ankle Injuries, Ankle Injuries and Disorders, Ankle Sprains
- Trial name
- NCT06499935
- Testing
- Rigid Taping, Kinesio-Taping
- Where
- Lebanon
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lateral Ligament, Ankle, Cartilage, Articular
Relevance of Osteochondral Lesions in Ankle Microinstability
The goal of this clinical trial is to learn if treating only the anterior talofibular ligament (ATFL) tear with ligament repair is as effective as treating both the ligament tear and the associated osteochondral lesion of the…
- Trial name
- NCT06947317
- Testing
- Arthroscopic anterior talofibular ligament repair, Talar chondral lesion treatment using microfracture technique
- Where
- Spain
- Volunteers
- 71 people
- Sponsor
- RAUL FIGA BARRIOS
Knee Osteoarthritis
Influence of Knee Alignment and Pelvis Rotation on Accuracy of Radiograph Measurements Before Total Knee Arthroplasty
The aim of this study is to determine the accuracy of long leg standing X-rays with respect to coronal alignment of the knee.
- Trial name
- NCT05277883
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 112 people
- Sponsor
- Valdoltra Orthopedic Hospital
Intermittent Claudication
Assess the Safety and Effectiveness of Once Daily PMR Compared to Twice Daily Pletaal® in Patients With Intermittent Claudication
The study is designed to compare the efficacy and safety of once daily PMR treatment with twice daily Pletaal® treatment in patients with intermittent claudication caused by peripheral arterial disease and are currently treated…
- Trial name
- NCT06886620
- Testing
- Cilostazol 200 mg, Cilostazol 100 mg
- Where
- 5 sites in Taiwan
- Volunteers
- 14 people
- Sponsor
- Genovate Biotechnology Co., Ltd.,
Paresis, Lumbar Disc Herniation
Validation of a Methodology Using Isometric Dynamometer for Ankle STrength Assessment to Quantify LDH-induced Paresis
Lumbar disc herniation (LDH) is a common condition that may cause lower limb motor weakness (paresis), particularly affecting ankle dorsiflexion and plantarflexion.
- Trial name
- VAST-LDH (NCT07763522)
- Testing
- Strength test validity and reliability
- Where
- Finland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Arthropathy of Ankle or Foot
Evaluation of Software Generated Customized Foot Orthoses
The purpose of this study is to determine whether custom-made foot orthoses generate a significant decrease in the perception of pain among individuals with foot pain and/or ankle pain.
- Trial name
- NCT05462912
- Testing
- custom foot orthotic
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Aging Problems
Dose-response of Talus Mobilizations
Ankle mobility limitations are common in older adults. A possible treatment to restore joint mobility is manual therapy based on mobilization techniques, in this case, applied on the ankle joint.
- Trial name
- ANKLE_ROM (NCT04360512)
- Testing
- Posteriorization of the talus
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cerebral Palsy (CP)
Optimized AFO Care For Children With Cerebral Palsy.
Ankle-foot orthoses (AFOs) are widely prescribed in children with cerebral palsy (CP) to improve their gait, enhance mobility and prevent secondary complications during growth.
- Trial name
- OPTI-CARE (NCT07811336)
- Testing
- Optimized AFO care
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Osteochondral Lesion of Talus, Chondral Defect
AMIC vs. MFx in the Ankle
This clinical investigation is a prospective, double blind, single-centre, randomised controlled trial comparing arthroscopic autologous matrix induced chondrogenesis (AMIC®) to microfracture alone in the treatment of…
- Conditions
- Osteochondral Lesion of Talus, Chondral Defect, Microfracture
- Trial name
- AMARTA (NCT05741983)
- Testing
- Microfracture (MFx), Chondro-Gide®
- Where
- United Kingdom
- Sponsor
- Geistlich Pharma AG
Ankle Sprains
Effect of Eccentric Streching vs IASTM of Gastrocnemius and Soleus Muscles in Athletes With Ankle Sprain
The primary objective within the current study is to compare the acute and chronic effects of eccentric training and IASTM on the dorsiflexion ROM.
- Trial name
- NCT06241001
- Testing
- eccentric streching, IASTM
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Riphah International University
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