Clinical trials: Ankle
Postoperative Pain
Catheter-based Peripheral Regional Anesthesia After Orthopedic Surgery to the Foot or Ankle
BACKGROUND Orthopedic surgery can be severely painful, and peripheral regional anesthesia is highly recommended as part of the perioperative pain treatment.
- Trial name
- API-FOOT (NCT03372304)
- Testing
- Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Nordsjaellands Hospital
Hypertension
A Study to Evaluate Methodologies for Measuring Swelling of the Leg and Ankle (MK-0000-106)(COMPLETED)
This study will evaluate methodologies for measuring pedal edema associated with calcium channel blockers in middle-aged and elderly subjects and patients with hypertension.
- Trial name
- NCT00789321
- Testing
- Comparator: amlodipine besylate
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Avascular Necrosis of the Talus
Patient Specific Talus Spacer Post Approval Study
Humanitarian Device Exemption Approved Patient Specific Talus Spacer Post Approval Study.
- Trial name
- NCT05364606
- Testing
- Patient Specific Talus Spacer
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Paragon 28
Ankle Sprain
the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain
Investigators recruited 208 patients with acute ankle sprain who were from the Rehabilitation Department of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2026 to November 2028.
- Trial name
- NCT07405281
- Testing
- hyperbaric oxygen therapy, non Hyperbaric Oxygen Therapy
- Volunteers
- 208 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Multiple Sclerosis
Targeted Lower Extremity Joint Training
The presence of foot drop limits normal gait. Our prior data has suggested that approximately 30% of MS patients have foot drop.
- Trial name
- NCT00765544
- Testing
- Anklebot, Lokomat
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- US Department of Veterans Affairs
Ankle Sprains
MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle Sprains
A Randomized, Multi-Center, Double-Blind, Factorial, Comparator and Placebo-Controlled Phase III Trial to Evaluate the Efficacy, Tolerability and Safety of MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Ankle…
- Trial name
- NCT01198834
- Testing
- MRX-7EAT, Lidocaine, Etodolac
- Where
- 33 sites in United States
- Volunteers
- 600 people
- Sponsor
- MEDRx USA, Inc.
Lower Extremity Amputation
Community Walking Trials: Comparing Prosthetic Feet
The purpose of the study is to obtain performance measurements and participant feedback about use of an investigational prosthetic foot compared to the participant's usual prosthetic foot.
- Trial name
- NCT03703232
- Testing
- Investigational prosthetic foot
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Washington
Pareses, Lower Extremity
C-Brace Prospective Registry
To gather prospective safety and effectiveness data for the C-Brace System following the standard of care.
- Trial name
- NCT04640584
- Testing
- C-Brace
- Where
- 76 sites in United States, Australia and 2 more
- Volunteers
- 250 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Lateral Ankle Instability, Chronic Lateral Ankle Instability
Brostrom Chronic Lateral Ankle Instability Repairs Augmented With BioBrace®
The purpose of this investigation is to evaluate pre- and post-operative patient reported outcomes and functional scores after open non-augmented Broström repair or open Broström repair augmented with the BioBrace Implant.
- Conditions
- Lateral Ankle Instability, Chronic Lateral Ankle Instability, Brostrom Procedure, ATFL
- Trial name
- NCT07708584
- Testing
- Standard Brostrom Repair, Brostrom repair with augmentation
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Foot Injuries and Disorders
SCANLOAD: The Effect of Limb Loading on Lower Limb Geometry
Orthotists currently use a range of weight bearing conditions when casting or scanning a patient's limb during the Ankle foot orthosis (AFO) fitting process.
- Trial name
- NCT04600102
- Testing
- Structure Sensor
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Ankle Sprains
Ankle Taping and Functional Ankle Instability
Background and purpose: Ankle inversion sprains are the commonest injuries of the lower extremities. Taping is routinely used after ankle sprain to support the joint and prevent reinjury.
- Trial name
- NCT03626051
- Testing
- Rigid tape, Fibular tape
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Ankle Osteoarthritis, Ankle - Recurrent Dislocation
Early MOtion Total Ankle Artroplasty
Evaluate the clinical and radiographic results of patients undergoing total ankle arthroplasty and treated in the post-operative period in a randomized manner with early mobilization of the ankle joint or with cast immobilization…
- Conditions
- Ankle Osteoarthritis, Ankle - Recurrent Dislocation, Cartilage Disease, Ankle Arthropathy
- Trial name
- EMOTAA (NCT06525545)
- Testing
- early mobilizzation of the ankle
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- Istituto Ortopedico Rizzoli
Electroacupuncture
Clinical Evaluation of Surrounding Electroacupuncture in the Treatment of Acute Lateral Ankle Sprain
Comparison and evaluation of the difference in clinical efficacy of electroacupuncture combined with surrounding acupuncture and sham electroacupuncture groups and control group (ice compress combined with brake rest group) in…
- Trial name
- NCT06182943
- Testing
- electroacupuncture combined with surrounding acupuncture, ice compress combined with brake rest
- Where
- China
- Volunteers
- 84 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Chronic Ankle Instability
Comparing Manipulation and Rehabilitation to Rehabilitation Only, in the Management of Chronic Ankle Instability
It is hypothesized that a combination approach would produce increased clinically and statistically significant outcomes as opposed to standard single intervention, inclusive of comparatively greater reduction in pain…
- Trial name
- NCT01196949
- Testing
- Manipulative and Rehabilitative Therapy, Rehabilitative Therapy
- Where
- South Africa
- Volunteers
- 30 people
- Sponsor
- Cleveland Chiropractic College
Charcot Arthropathy of Hindfoot
Hindfoot Fusion Using Intramedullary Nail in Diabetic Ankle Arthropathy
The aim of this study is to evaluate the outcome of healing rate of ankle fusion using modified retrograde IM femoral nail with plate in charcot ankle
- Trial name
- NCT05717816
- Testing
- intramedullary nail and plate
- Volunteers
- 20 people
- Sponsor
- Ehab Ahmed Mohamed
Diastasis Recti
Effects of Drawing in Maneuver and Resisted Ankle Dorsiflexion in Postpartum Diastasis Recti
The aim of this study is to compare the combine effects of drawing in maneuver and resisted ankle dorsiflexion on pain, inter-recti distance, strength and quality of life in postpartum diastasis recti.
- Trial name
- NCT07520409
- Testing
- DRAWING IN MANEUVER, RESISTED ANKLE DORSIFLEXION
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Sprain of Ankle
Use of Platelet Rich Plasma Therapy for Acute Ankle Sprains in the Emergency Department
This research study hopes to determine whether or not platelet rich plasma therapy improves healing time of moderate to severe ankle sprain in comparison to standard of care therapy.
- Trial name
- PRP (NCT01518335)
- Testing
- Platelet rich plasma injection
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Albert Einstein Healthcare Network
Ankle Sprains
Manual Therapy, Kinesiotape and Strength Training in Soccer Players With Recurrent Ankle Sprains
Introduction. The ankle sprain is one of the most prevalent injuries in soccer players. The muscle strength deficit is one of the variables that can most influence the development of a sprain.
- Trial name
- NCT04257916
- Testing
- Experimental, Manual therapy group
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Chronic Ankle Instability
Short-Term and Long-Term Effects of Ankle Joint Taping and Bandaging on Balance, Proprioception and Vertical Jump Among Volleyball Players With Chronic Ankle Instability
Objective: This study aimed to 1) investigate the long-term effect of taping and bandaging on proprioception, balance, and vertical jump among volleyball players with ankle instability, 2) Compare the short-term effects of taping…
- Trial name
- NCT04377269
- Testing
- Taping and Bandaging
- Volunteers
- 100 people
- Sponsor
- Istanbul Gelisim University
Ankle Fractures
Postoperative Aspirin and Ankle Fracture Healing
This study aims to identify if postoperative aspirin use leads to a delay in fracture healing. NSAIDs have long been avoided in the management of fractures, due to the belief that they may impair fracture healing.
- Trial name
- NCT03765619
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.