Clinical trials: Ankle
Swelling/ Edema
The Efficacy and Safety of Venostan in Promoting Postoperative Swelling Reduction in Patients With Ankle Fractures
This study is a multicenter, open-label, randomized controlled trial planned to enroll patients with ankle fractures who meet the inclusion and exclusion criteria and are scheduled to undergo internal fixation surgery from the…
- Trial name
- NCT06872034
- Testing
- Venostasin (horse chestnut seed extract tablets), standard treatment
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Beijing Jishuitan Hospital
Diabetes Mellitus, Coronary Artery Disease,
Young Toe-Brachial Index Assessment
The Toe-Brachial Index (TBI) that has been using in our laboratory is 0.6, but the average value we measured in normal individuals is about 1.0, furthermore, we can not find out the reference of TBI that is currently being used.
- Conditions
- Diabetes Mellitus, Coronary Artery Disease,, Vascular Diseases
- Trial name
- TBI (NCT02020850)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Rehabilitation
Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures
The overall objective of this study is to compare outcomes following early versus delayed weight bearing for adult patients operatively treated for an ankle fracture without syndesmotic fixation.
- Trial name
- NCT04028414
- Testing
- Early Weight Bearing
- Where
- 17 sites in United States
- Volunteers
- 435 people
- Sponsor
- Major Extremity Trauma Research Consortium
Ankle Injuries
Ankle Instability Treatment in Patients With Chronic Ankle Instability
Ankle joint self mobilization.
- Trial name
- NCT03189784
- Testing
- mobilization with movement techniques
- Where
- 2 sites in Spain
- Volunteers
- 52 people
- Sponsor
- University of Jaén
Ankle Sprains, Ankle Injuries
The Effect of Different Talocrural Joint Mobilization Techniques in Lateral Ankle Sprain
Decreased ankle dorsiflexion range of motion (DFROM) has been identified among the factors that increase the risk of lateral ankle sprain (LAS) in basketball players.
- Conditions
- Ankle Sprains, Ankle Injuries, Kinesiophobia, Jumping From Height
- Trial name
- NCT06295198
- Testing
- Single lep drop jump test
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Bahçeşehir University
Diabetes Mellitus, Diabetic Foot Ulcer
Effect of Electromagnetic Field Therapy and Customized Foot Insole on Peripheral Circulation and Ankle-Brachial Pressure Index in Patients With Diabetic Foot Ulcer
Diabetic foot ulcers (DFUs) are a significant complication of diabetes mellitus, associated with poor peripheral circulation, neuropathy, and increased risk of lower-limb amputation.
- Trial name
- NCT07070544
- Testing
- Electromagnetic Field Therapy: • Frequency: 50 Hz • Intensity: 5-30 mT • Duration: 30 minutes/session • Frequency: 3 sessions/week for 8 weeks Customized Foot Insoles: • Individually tailored based on
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- South Valley University
Peripheral Arterial Disease
To Investigate the Effect of Far-infrared Radiation on Lower Extremity Acupoints on the Blood Circulation of Lower Extremities in Patients With Hemodialysis
This study intends to irradiate the acupoints of both lower extremities of hemodialysis patients with far-infrared therapeutic apparatus to explore its effect on foot blood circulation, peripheral artery occlusion disease (PAOD)…
- Trial name
- NCT05822960
- Testing
- far-infrared radiation
- Where
- 2 sites in Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Acute Pain, Ankle Sprain
Diclofenac Patch for Treatment of Acute Pain Due to Mild to Moderate Ankle Sprain
The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium topical patch in reducing acute pain due to mild to moderate ankle sprains when applied to the painful area.
- Trial name
- SUPPORT 2 (NCT00869180)
- Testing
- Diclofenac Sodium
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Cerimon Pharmaceuticals
Chronic Ankle Instability
A Test Battery for Evaluation of Muscle Strength, Balance and Functional Performance in Subjects With Chronic Ankle Instability
Purpose: The primary aim of this study was to investigate subjects with chronic ankle instability regarding strength, balance and functional performance with an easily used test battery that required minimal equipment.
- Trial name
- NCT05732168
- Testing
- A test battery for evaluation of muscle strength, balance and functional performance
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Linnaeus University
Chronic Ankle Instability
Simplified Tai Chi Exercises to Improve Function in People With Chronic Ankle Instability
The goal of this interventional trial is to evaluate the effectiveness of the simplified four-week Tai Chi training in improving function in people with chronic ankle instability. The main questions it aims to answer are: 1.
- Trial name
- NCT06682897
- Testing
- Tai Chi training
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Injury of Musculoskeletal System
Study of the Effect of Kinesio Taping and Proprioceptive Exercise on the Stability of Ankle in Amateur Soccer Players
Soccer is a sport that attracts many participants and leads to a substantial number of injuries, especially of the ankle. Enhancement of functional joint stability by kinesio taping proprioceptive training may be important both…
- Trial name
- NCT02863562
- Testing
- Kinesio taping, Proprioceptive exercises
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Chronic Ankle Instability, CAI, Healthy Participants
The Effect of Cognitive Tasks on Single Limb Balance
Purpose of the Study: The purpose of this study is to evaluate the effects of performing various cognitive tasks on balance in individuals with chronic ankle instability and healthy controls.
- Trial name
- NCT07084220
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Towson University
Hemiparesis;Poststroke/CVA
Immediate Effect of Ankle Mobilization on Active Range of Motion and Gait in Subacute Stroke
The goal of this observational study is to determine the effect of ankle joint mobilization on active range of motion and gait in subacute first-time stroke.
- Trial name
- NCT06109194
- Testing
- Joint mobilization
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Loma Linda University
Tranexamic Acid, Knee Osteoarthritis
Tranexamic Acid in Major Orthopedic Surgery: Comparison of 3 Dosage Regimen
Tranexamic acid has been shown to be effective in reducing blood loss and transfusion in orthopedic surgery. It remains unknown the ideal therapeutic regimen.
- Conditions
- Tranexamic Acid, Knee Osteoarthritis, Ankle Osteoarthritis, Bleeding
- Trial name
- NCT03573245
- Testing
- Tranexamic Acid
- Volunteers
- 210 people
- Sponsor
- CUF Santarém Hospital
Achilles Tendon Surgery, Cerebral Palsy
Gastrocsoleus Lengthening in Cerebral Palsy
The goal of this study is to compare passive ankle and knee range of motion (ROM) development after surgery to the gastrocsoleus complex, in children with cerebral palsy (CP).
- Trial name
- NCT05783739
- Volunteers
- 186 people
- Sponsor
- Region Skane
Ankle Arthritis
Treatment of Post Traumatic Asymmetrical Ankle Arthritis Using Low Tibial Osteotomy
Evaluation of joint preserving procedure for asymmetrical ankle arthritis regarding the improvement of alignment and its effect on symptoms
- Trial name
- NCT04100746
- Testing
- supramalleolar osteotomy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Ankle Osteoarthritis
Evaluating Intra-articular Injection of Axolotl Ambient Compared to Saline in Subjects With Ankle Osteoarthritis
A Double-blind, Multi-Center, Prospective, Randomized Placebo-controlled Pilot Study Evaluating Intra-articular Injection of Axolotl Ambient Compared to Saline in Subjects with Ankle Osteoarthritis.
- Trial name
- Phoenix (NCT05092646)
- Testing
- Axolotl Ambient
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Axolotl Biologix
Peripheral Artery Disease
Peripheral Artery Disease in Patients With Stable Coronary Artery Disease in General Practice: Prevalence, Management and Clinical Outcomes.
Patients with lower extremity peripheral artery disease (PAD) are at risk of developing major adverse limb events and have a similar cardiovascular (CV) morbidity and mortality to those with coronary artery disease (CAD) with…
- Trial name
- PAD&CAD (NCT03921905)
- Testing
- ABI measurement
- Where
- 4 sites in Italy
- Volunteers
- 713 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Chronic Instability of Joint
Effects of Two Techniques of Mobilization in the Dorsiflexion on Patients With Chronic Ankle Instability
Restrictions on ankle dorsiflexion are common in subjects with chronic ankle instability (CAI). In fact, this is one factor that can contribute to the recurrence of such injuries.
- Trial name
- NCT01618032
- Testing
- HVLA, MWM
- Volunteers
- 52 people
- Sponsor
- CEU San Pablo University
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