Clinical trials: Ankle Arthritis
Arthritis, Infection of Total Ankle Joint Prosthesis
INBONE™ Total Ankle Prosthesis With Long Talar Stem
The primary objective of this study is to collect preoperative, operative and postoperative clinical assessments of patients that qualify for surgical implantation of the INBONE™ Total Ankle Prosthesis.
- Trial name
- NCT01641848
- Testing
- INBONE™ Total Ankle Prosthesis with Long Talar Stem
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stryker Trauma and Extremities
Knee Osteoarthritis
Influence of Knee Alignment and Pelvis Rotation on Accuracy of Radiograph Measurements Before Total Knee Arthroplasty
The aim of this study is to determine the accuracy of long leg standing X-rays with respect to coronal alignment of the knee.
- Trial name
- NCT05277883
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 112 people
- Sponsor
- Valdoltra Orthopedic Hospital
Knee Osteoarthritis (OA)
Effects of Core Stabilization Exercises Versus Foot-Ankle Strengthening Program in Patients With Knee Osteoarthritis.
Knee osteoarthritis (OA) is also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. It is most common in the elder population.
- Trial name
- NCT06658249
- Testing
- Core Stabilization Exercises with Foot-Ankle Strengthening Program, Foot-Ankle Strengthening Program
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Hip Disease, Heart Failure
How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups?
EQ-5D is one of the most commonly employed patient-reported outcome (PRO) measures. It is included in many of the Swedish National Quality Registers (NQRs).
- Conditions
- Hip Disease, Heart Failure, Psoriasis, Fractures, Bone
- Trial name
- SWEQR (NCT04359628)
- Where
- Sweden
- Volunteers
- 700,000 people
- Sponsor
- Vastra Gotaland Region
Hallux Rigidus, Hallux Limitus
Short Term Follow-up of Patient Implanted With the Metatarso-Phalangeal Prosthesis METIS®
The great toe is vital for normal, pain free ambulation. Decreased function associated with osteoarthritis of the first matatarsal phalangeal joint (MTP I) often called Hallux Rigidis or Hallux Limitus leading to a painful great…
- Conditions
- Hallux Rigidus, Hallux Limitus, Hallux Valgus, Osteoarthritis
- Trial name
- NCT01284985
- Where
- 4 sites in Czechia, Netherlands and 2 more
- Volunteers
- 60 people
- Sponsor
- Integra LifeSciences Services
Degenerative Arthritis, Rheumatoid Arthritis
Long Term Follow-up of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement
This study will evaluate the long term performance and safety data for the Cadence™ Total Ankle System (CTAS) when used for primary arthroplasty in patients with primary arthritis (e.g.
- Conditions
- Degenerative Arthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Trial name
- NCT03247023
- Testing
- Implantation of Integra Cadence Total Ankle System
- Where
- 6 sites in Belgium, Canada and 3 more
- Volunteers
- 65 people
- Sponsor
- Smith & Nephew, Inc.
Knee Osteoarthritis
Effect of Core Stability Versus Ankle Foot Strengthening Exercise in the Management of Knee Osteoarthritis
Knee osteoarthritis (KOA) is a degenerative joint disease causing pain, stiffness, and reduced quality of life. While treatments often focus on drugs or surgery, noninvasive exercises like core stabilization and ankle/foot…
- Trial name
- NCT06766877
- Testing
- core stability exercise, foot-ankle strengthening exercise
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Dow University of Health Sciences
Arthritis Foot, Trauma Injury
Artoss Foot and Ankle Surgery Registry
This prospective registry was designed as an observational study to ascertain how commercially available NanoBone products are being used by surgeons performing foot and ankle surgery which involves bone grafting, as well as…
- Conditions
- Arthritis Foot, Trauma Injury, Deformity; Bone
- Trial name
- ARK (NCT04503759)
- Testing
- NanoBone Bone Graft Substitute
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- Artoss Inc.
Osteoarthritis, Rheumatoid Arthritis
Ankle Joint Replacement Outcomes Study
This post market outcome study will look at the therapeutic results of the Salto Talaris Anatomic ankle prosthesis. The study population will consist of patients who will undergo an ankle arthroplasty procedure with a Salto…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis, Septic Arthritis
- Trial name
- NCT00503438
- Testing
- Salto Talaris Ankle
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
Platelet Rich Plasma for Musculoskeletal Conditions
The primary purpose of this study is to follow patients with various musculoskeletal (MSK) conditions over a one-year follow-up period after receiving a platelet rich plasma (PRP) injection, assessing changes in their pain…
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder
- Trial name
- PRP for MSK (NCT07231471)
- Testing
- Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Tranexamic Acid, Knee Osteoarthritis
Tranexamic Acid in Major Orthopedic Surgery: Comparison of 3 Dosage Regimen
Tranexamic acid has been shown to be effective in reducing blood loss and transfusion in orthopedic surgery. It remains unknown the ideal therapeutic regimen.
- Conditions
- Tranexamic Acid, Knee Osteoarthritis, Ankle Osteoarthritis, Bleeding
- Trial name
- NCT03573245
- Testing
- Tranexamic Acid
- Volunteers
- 210 people
- Sponsor
- CUF Santarém Hospital
Rheumatoid Arthritis
Neuropathic Foot and Ankle in Rheumatoid Arthritis : Ultrasound and Nerve Conduction Study
1. To measure the prevalence of Neuropathic pain in Rheumatoid arthritis patients with ankle and foot pain 2. To evaluate the role of Neuromuscular Ultra sound (NMUS) and nerve conduction study (NCS) in assessment of Neuropathic…
- Trial name
- NCT04550884
- Testing
- neuromascular ultrasound
- Volunteers
- 80 people
- Sponsor
- Assiut University
Total Knee Replacement, Knee Osteoarthritis
Circulatory Exercise After Total Knee Replacement
Total knee replacement is commonly associated with early postoperative inflammation, edema, pain, and reduced mobility. This randomized controlled trial will evaluate whether adding a simple circulatory exercise program to…
- Conditions
- Total Knee Replacement, Knee Osteoarthritis, Postoperative Edema, Postoperative Inflammation
- Trial name
- NCT07688642
- Testing
- standard postoperative TKR rehabilitation, Standard Rehabilitation Plus Circulatory Exercise
- Volunteers
- 68 people
- Sponsor
- Assiut University
Osteoarthritis, Osteoarthritis, Knee
Outcomes of Low-Impact Exercise Program for People With Ankle, Knee, and/or Hip Pain
The primary objective of this study is to study how low-impact group exercise classes affect pain scores in patients with knee, hip, and ankle pain when paired with concurrent standard of care dietitian and behavioral health…
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Ankle
- Trial name
- NCT03711773
- Testing
- Group Physical Therapy Classes
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- University of Missouri-Columbia
Ankle Fractures, Post-traumatic Osteoarthritis
Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
The proposed study evaluates the effect of carbon fiber brace design on forces across the ankle joint. Research suggests that ankle arthritis develops after ankle fracture, in part, due to elevated forces on the cartilage.
- Conditions
- Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
- Trial name
- PRMRP-FPA2 (NCT04562896)
- Testing
- Custom Carbon Fiber Dynamic Orthosis (CDO)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Knee Osteoarthritis, Knee Arthritis
Maximal Rate of Force Development of Ankle Muscles and Functional Ability in Patients With Knee Osteoarthritis
This study is a detailed assessment of the maximal rate of force development of ankle muscles and its association with functional ability in patients with knee osteoarthritis (OA).
- Trial name
- NCT06063889
- Testing
- Maximal Rate of Force Development Test for Ankle Muscles
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Ankle Fractures, Osteoarthritis, Ankle
Stability of Distal Tibiofibular Syndesmosis With or Without Fixation of Posterior Fragments in Bimalleolar Fractures
Background and Rationale: Injury to the tibiofibular syndesmosis in ankle fractures is a major prognostic factor for the development of post-traumatic osteoarthritis.
- Trial name
- SYNDESMOSE (NCT07755462)
- Testing
- Surgical management of bimalleolar ankle fractures with osteosynthesis of the posterior fragments., Surgical management of bimalleolar ankle fractures without osteosynthesis of the posterior fragments
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Primary Arthrosis
Post-Approval Study to Investigate the Long Term (8 Year) Survivorship of STAR Ankle Among Continued Access Study Patients
The purpose of this study is to examine the long term survivorship of the Scandinavian Total Ankle Replacement (STAR). Specifically, this study focuses on the revision and/or removal rate of any component of the STAR ankle.
- Trial name
- STAR 8 (NCT01288586)
- Testing
- Scandinavian Total Ankle Replacement System (STAR Ankle)
- Where
- 5 sites in United States
- Volunteers
- 87 people
- Sponsor
- Stryker Trauma and Extremities
Osteoarthritis
26 Week Open Label Study Evaluating Single IA Injection of DUROLANE SJ for Treatment of Osteoarthritis Pain of the Ankle
26 week open label study of treatment with Durolane for OA pain of the ankle
- Trial name
- NCT02627859
- Testing
- Durolane SJ
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Bioventus LLC
Primary Arthrosis, Post Traumatic Arthritis
2-Year Post-Approval Study to Investigate the Scandinavian Total Ankle Replacement System (STAR) Ankle Under Actual Conditions of Use
This post-approval study is being conducted to examine the performance of the STAR Ankle under actual conditions of use.
- Conditions
- Primary Arthrosis, Post Traumatic Arthritis, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- STAR 2 PAS (NCT01284283)
- Testing
- Scandinavian Total Ankle Replacement System (STAR Ankle)
- Where
- 9 sites in United States
- Volunteers
- 102 people
- Sponsor
- Encore Medical, L.P.