Clinical trials: Ankle Disorders Injuries
Ankle Fracture
Exparel and Ankle Surgery
This study involves a drug called Exparel that has been approved by the US Food and Drug Administration (FDA), for application directly to wound sites. EXPAREL® is a long acting pain reliever.
- Trial name
- NCT02072135
- Testing
- Exparel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Rutgers, The State University of New Jersey
Ankle Sprain, Ankle Sprain 1St Degree
Effectiveness of a Telerehabilitation Program in Ankle Sprain
Ankle sprain is the most common sprain. Their care entails a high cost due to the incapacity for work that it generates. An early and timely intervention for the treatment of ankle sprain reduces the days of disability and…
- Conditions
- Ankle Sprain, Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
- Trial name
- NCT05217173
- Testing
- telerehabilitation
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- Instituto Mexicano del Seguro Social
Bunion of Unspecified Foot, Bunionette of Unspecified Foot
Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study
Orthopedic surgeons frequently prescribe and over-prescribe narcotic pain medications during the postoperative period, despite the ongoing opioid crisis in the United States.
- Conditions
- Bunion of Unspecified Foot, Bunionette of Unspecified Foot, Hammertoe, Ankle Fractures
- Trial name
- NCT04771741
- Testing
- Acetominophen, Toradol, Meloxicam
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Prisma Health-Midlands
Arthritis, Rheumatoid Arthritis
Wright Foot & Ankle Post-Market Observational Study
WRIGHT FOOT \& ANKLE POST-MARKET OBSERVATIONAL STUDY, Multi-Year, Multi-Site, Multi-Device, Post-Market Observational Study, 10 sites, a minimum of 40 patients per device
- Conditions
- Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury
- Trial name
- NCT04118894
- Testing
- Foot and Ankle Devices
- Where
- 5 sites in United States, France and 2 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Ankle Injuries, Foot Injuries
Ankle Trauma: an Emergency Nurse Assessment Study
The ankle and/or foot injuries incidence is high. Lateral ankle sprains are most common diagnosis, while fractures represent less than 15% of final diagnosis.
- Conditions
- Ankle Injuries, Foot Injuries, Diagnosis, Treatment
- Trial name
- ATENA (NCT04126837)
- Testing
- Diagnosis and treatment
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Grenoble
Ankle Injuries, Ankle Inversion Sprain
Effects of Gait Retraining With Auditory Feedback
There is evidence to support individuals with chronic ankle instability (CAI) have altered gait biomechanics which may lead to re-injury and poor patient outcomes.
- Trial name
- NCT04302961
- Testing
- Auditory Feedback, No Feedback
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of North Carolina, Charlotte
Ankle Injuries and Disorders, Foot Injuries and Disorders
The Aim of Study is Translate and Adapt the Visual Analog Scale Foot and Ankle (VAS-FA) Instrument Into Turkish and Psycho-metrically Test Its Reliability and Validity Among Patients Who Had Foot and Ankle Disorders or Surgery
There have previously been no validated a specific foot and ankle patient-reported outcome measures in Turkish. The Visual Analogue Scale Foot and Ankle (VAS-FA) will translated and adapted into Turkish language.
- Trial name
- NCT03262324
- Testing
- VAS-FA Turkish version
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Hasan Kalyoncu University
Ankle Sprain
Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Applied 4 Times Daily in Subjects With Acute Ankle Sprain
The purpose of this study is to evaluate the efficacy of Diclofenac Sodium Topical (DSG) 1% compared with placebo applied four times a day in subjects with acute ankle sprains under 'in-use' conditions, in particular with regard…
- Trial name
- NCT01255423
- Testing
- Diclofenac sodium topical gel 1%
- Where
- 9 sites in United States
- Volunteers
- 206 people
- Sponsor
- Novartis
Ankle Sprain
Changes in Brain-Muscle Coupling After Microneedle-Knife Therapy for Ankle Sprain
This study evaluated changes in brain-muscle coordination in patients with ankle sprain after one session of microneedle-knife therapy.
- Trial name
- NCT07839260
- Testing
- Microneedle-Knife Therapy
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Affiliated Dongyang Hospital of Wenzhou Medical University
Ankle Fractures
Impact of Suture Technique on Wound Healing in Ankle Fracture Surgery: A Randomized Controlled Trial
Our primary aim is to compare the complication rates of patients with ankle fractures who underwent skin closure using a running subcuticular suture pattern compared to an interrupted suture pattern.
- Trial name
- NCT06496698
- Testing
- Simple Interrupted Suture, Subcuticular Suture
- Volunteers
- 80 people
- Sponsor
- University of Puerto Rico
Osteoporotic Fractures, Hip Fractures
Prediction and Secondary Prevention of Fractures
The purpose of this study is to investigate patient related factors that contribute to increased risk of recurrent fractures and to investigate patient adherence to prescribed anti-osteoporotic drugs.
- Conditions
- Osteoporotic Fractures, Hip Fractures, Wrist Fractures, Ankle Fractures
- Trial name
- NOFRACTsub (NCT02608801)
- Where
- 6 sites in Norway
- Volunteers
- 840 people
- Sponsor
- Oslo University Hospital
Ankle Instability, Platelet-rich Plasma
Platelet-rich Plasma for Chronic Lateral Ankle Instability
This study aims to evaluate the effect of platelet-rich plasma (PRP) on chronic lateral ankle instability by comparing the imaging and clinical outcomes between patients receiving PRP and those receiving whole blood during the…
- Trial name
- NCT03197428
- Testing
- Platelet-rich plasma, Control
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Pei-Yuan Lee, MD
Ankle Injuries
Comparative Results of Conservatively and Surgically Treated Adolescents With Triplane and Juvenile Tillaux Ankle Fractures After Skeletal Maturity
Triplane and Juvenile Tillaux fractures of the ankle are well known in adolescent pediatric population. It is widely accepted, that optimal treatment for displaced fractures is close or open reduction and fixation with screws…
- Trial name
- NCT00541580
- Sponsor
- Hadassah Medical Organization
Ankle Injuries, Balanced
Kinesio Taping Effects on Balance and Ankle Proprioception
Ankle injuries are among the most common musculoskeletal injuries, affecting both athletes and the general population. Various methods are used to prevent such injuries, but the effectiveness of different kinesio taping…
- Trial name
- NCT06832111
- Testing
- Kinesio Taping 1, Kinesio Taping 2
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Hip Fractures, Tibial Fractures
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment.
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
- Trial name
- NCT04113044
- Testing
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 1,500 people
- Sponsor
- AO Innovation Translation Center
Instability, Joint, Ankle Sprains
Italian Version of The Cumberland Ankle Instability Tool (CAIT)
Study Design: Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. Objective: Translating, culturally adapting, and validating the Italian version of the Cumberland Ankle Instability Tool…
- Conditions
- Instability, Joint, Ankle Sprains, Ankle Injuries, Sport Injury
- Trial name
- CAIT-I (NCT04644601)
- Where
- Italy
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Spastic Cerebral Palsy (sCP), Acquired Brain Injury
Impact of AFOs on the GMF of Children With CP or ABI
Children with cerebral palsy (CP) or an acquired brain injury (ABI) are often prescribed ankle-foot orthoses (AFOs) to correct impairments of muscles and/or to prevent contractures and bony deformities.
- Trial name
- NCT06930963
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ankle (Ligaments); Instability (Old Injury), Ankle Sprain
A Study on Reducing Opioid Use After Ankle Arthroscopy
Study Title Effect of a Postoperative Multimodal Analgesic Protocol Predominantly Based on Non-Opioid Medications vs Opioid-Based Analgesia on Pain After Ankle Arthroscopy: A Noninferiority Randomized Clinical Trial Purpose This…
- Conditions
- Ankle (Ligaments); Instability (Old Injury), Ankle Sprain, Talus Osteochondral Defect, Opioid Analgesia
- Trial name
- NCT07154433
- Testing
- Opioid Analgesic Regimen, Non-opioid analgesic regimen
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ankle Sprains
Management of Acute Lateral Ankle Sprains
This study evaluates the effectiveness of pain guided early weight bearing as a means to enhance the outcome of acute lateral ankle sprain.
- Trial name
- NCT03527121
- Testing
- ESP physiotherapy, Usual care
- Where
- 2 sites in Denmark
- Volunteers
- 112 people
- Sponsor
- Christian Olsen