Clinical trials: Ankle Foot Injury
Injuries, Ankle, Sprain of Foot
Multisegmented Foot Motion in Patients With Lateral Ankle Sprains and Chronic Ankle Instability
Lateral ankle sprains (LAS) and chronic ankle instability (CAI) are common musculoskeletal injuries that are a result of inversion injury during sport.
- Trial name
- NCT02697461
- Testing
- Intrinsic Foot Strengthening, Joint Mobilization
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Foot Injury
From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices
This study is designed to support evidence-based practice and optimal care by evaluating how different configurations of two types of carbon fiber custom dynamic orthoses (CDOs) influences outcomes following traumatic lower…
- Trial name
- AFOSVA (NCT06352788)
- Testing
- Modular Carbon Fiber Custom Dynamic Orthosis (CDO), Mono Carbon Fiber Custom Dynamic Orthosis (CDO)
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Jason Wilken
Rotator Cuff Injuries, Shoulder Disease
Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery
Postoperative pain remains undertreated with inadequate analgesic options. Opioids have well-known limitations for both individuals and society; single-injection and continuous peripheral nerve blocks provide intense analgesia…
- Conditions
- Rotator Cuff Injuries, Shoulder Disease, Hallux Valgus, Ankle Arthropathy
- Trial name
- NCT06818708
- Testing
- Experimental Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Lower Limb Amputation at Ankle (Injury)
Comparing New Prothesis PROPRIO-FOOT® Versus Usual Prothesis Tasks Tibial Amputees
Evaluate a new porosthetic device in lower limb amputees.
- Trial name
- PROPRIO-FOOT (NCT02501408)
- Testing
- propriofoot prosthesis
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Diabetic Foot, Orthopedic Disorder
Clinical Efficacy of a 3D Foot Scanner for the Therapeutic Footwear Fitting
Patients with diabetes at high risk of ulceration require a perfect fitting shoe to avoid high shear and pressure forces. Neuropathy skews sensory perceptions and can alter the proper selection of the therapeutic footwear.
- Conditions
- Diabetic Foot, Orthopedic Disorder, Foot Ankle Injuries
- Trial name
- Smartfitting (NCT05353114)
- Testing
- 3D feet scan (smart-fitting by Podiapp - Podartis s.r.l Unipersonale-Crocceta del Montello (TV), Italy).
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Spinal Cord Injuries, Poliomyelitis
Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis
The study will specifically evaluate the potential of the C-Brace to improve the functional mobility and quality of life in individuals with lower extremity impairments due to neurologic or neuromuscular disease, orthopedic…
- Conditions
- Spinal Cord Injuries, Poliomyelitis, Post-polio Syndrome, Arthritis
- Trial name
- NCT02089880
- Testing
- C-brace, Stance control orthosis
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Shirley Ryan AbilityLab
Foot Fusion
Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions
STUDY OBJECTIVES: Demonstrate equivalent clinical and radiologic outcomes to the "gold standard" (ABG) in a representative clinical model (hindfoot and ankle fusions) STUDY HYPOTHESIS: Augment® Bone Graft is an equivalent bone…
- Trial name
- NCT00583375
- Testing
- Augment® Bone Graft, Standard of Care
- Where
- 37 sites in United States, Canada
- Volunteers
- 414 people
- Sponsor
- BioMimetic Therapeutics
Ankle Injuries
A Prospective Study Comparing Different Clinical Decision Rules in Adult and Pediatric Ankle Trauma
Comparison of the reliability of different examination techniques to detect fractures in patients with ankle trauma.
- Trial name
- LEFO (NCT01205841)
- Testing
- Ottawa Ankle and Foot Rules, Buffalo Rule, Ottawa Ankle and Foot Rules + application of a tuning fork to the distal fibula and tibia
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- KU Leuven
Leg Injuries, Ankle Injuries
Medico Economic Evaluation of Dermal Substitute Integra® for Coverage of Inferior Limb Traumatic Skin Loss
Comparison of 2 techniques of surgery on patients with inferior limb traumatic wounds: the innovative technique Integra® and the technique of reference: the flap surgery.
- Conditions
- Leg Injuries, Ankle Injuries, Foot Injuries
- Trial name
- INTEGRA® (NCT00906672)
- Testing
- INTEGRA®, Flap technique
- Where
- 7 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Bordeaux
Lower Limb; Fusion, Congenital, Lower Limb Fracture
Investigating Auto Adjusting Dynamic AFO
Offloading Ankle Foot Orthoses (AFOs) are devices designed for people following lower-limb reconstruction to restore mobility by reducing mechanical loading through the injury site and redistributing it proximally.
- Conditions
- Lower Limb; Fusion, Congenital, Lower Limb Fracture, Ankle Foot Injury
- Trial name
- NCT04623853
- Testing
- Variable Stiffness AFO
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Washington
Ankle Disease, Ankle Injuries and Disorders
Dexmedetomidine Vs Dexamethasone in Popliteal Nerve Block
Effect of Perineural Dexmedetomidine vs. Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery.
- Conditions
- Ankle Disease, Ankle Injuries and Disorders, Foot Injury, Foot Diseases
- Trial name
- NCT06304324
- Testing
- 0.9% Sodium chloride, 0.1mg/kg Dexamethasone, 0.05ug/kg Dexmedetomidine
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Foot Ulcer
Functional Ankle Taping Correction on Plantar Foot Ulcer Healing in Diabetic Patients
This study will investigate the effects of Functional ankle taping correction on plantar foot ulcer healing in diabetic patients.
- Trial name
- NCT06065488
- Testing
- ankle kinesio tap
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- MTI University
Pain, Postoperative, Pain, Acute Postoperative
Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery
Liposomal Bupivacaine (Exparel) has been recently studied as the active agent utilized in various nerve block. Due to its liposomal form allowing for extended delivery, Exparel has been used in various peri-operative nerve blocks…
- Conditions
- Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
- Trial name
- NCT05494645
- Testing
- Exparel, Peripheral Nerve Block
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- St. Luke's Hospital, Pennsylvania
Foot Ankle Injuries
Compare Continuous Gastrocnemius Plane Block With Intravenous Analgesia After Foot and Ankle Surgery
This study aims to evaluate the efficacy and safety of a continuous gastrocnemius plane block for perioperative analgesia in patients undergoing foot and ankle surgery under elective general anesthesia.
- Trial name
- NCT05463809
- Testing
- Continuous Gastrocnemius plane block with ropivacaine, oxycodone
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Diabetic Foot Ulcer, Wound Healing
Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle Surgery
This observational prospective cohort study will evaluate whether routine blood tests are associated with the functional quality of calcaneal bone marrow aspirate mesenchymal stem cells in adults undergoing clinically indicated…
- Conditions
- Diabetic Foot Ulcer, Wound Healing, Foot Ulcer Due to Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2
- Trial name
- IQF-BMA (NCT07802106)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Sao Francisco