Clinical trials: Ankle Fracture
Ankle Injuries
A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
The role of operative fixation of unstable, displaced lateral malleolus fractures is well-established (Mayer, Mak, and Yablon). However, the optimal type of fixation remains the subject of debate.
- Trial name
- NCT00718302
- Testing
- Antiglide Plate, Lateral Plate
- Where
- 10 sites in United States, Canada
- Volunteers
- 249 people
- Sponsor
- Boston Medical Center
Ankle Fractures, Surgery
Immediate Weight-Bearing Ankle Study
This single-centre historical control group comparative study will compare outcomes of surgically-treated rotational ankle fractures and the current routine practice of early protected weightbearing and range of motion with…
- Trial name
- NCT03032653
- Testing
- Late Rehabilitation, Early Rehabilitation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Fraser Orthopaedic Research Society
Hyperpronated Foot, Reconstruction Surgeries of the Foot
Evaluate the Continued Safety and Performance of the Foot and Ankle Products
The objective of the registry is to evaluate the continued safety and performance of Arthrex foot and ankle products, including the ProStop® implant for hyperpronated foot; Bio-Compression Screw for reconstruction surgeries of…
- Conditions
- Hyperpronated Foot, Reconstruction Surgeries of the Foot, Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle, Fixation of Small Bone Fragments of the Foot/Ankle
- Trial name
- NCT04715139
- Testing
- Products listed in Group/Cohort Description
- Where
- 7 sites in United States, Germany and 1 more
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Arthrex, Inc.
Ankle Fractures, Foot Fracture
Waterproof Casting Versus Standard Casting for Short Leg Walking Casts
The purpose of the study is to determine whether the use of waterproof padding in short leg walking casts will lead to an increase in cast-related complications, as compared to the standard non-waterproof casting in children.
- Conditions
- Ankle Fractures, Foot Fracture, Ankle Sprains, Foot Sprain
- Trial name
- NCT04961957
- Testing
- Waterproof padding, Non-waterproof padding
- Where
- United States
- Sponsor
- West Virginia University
Ankle Fractures
Outcome of Low Energy Ankle Fractures
Ankle fractures are among the most common osseous injuries to the lower extremity, and remain a significant source of morbidity for both the young and the elderly.
- Trial name
- NCT03212768
- Testing
- Trans-syndesmotic fixation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long term effectiveness and safety of AUGMENT® Bone Graft vs. autologous bone graft.
- Trial name
- NCT02879149
- Testing
- AUGMENT® Bone Graft, Standard of Care
- Where
- 26 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- BioMimetic Therapeutics
Postoperative Pain
Peripheral Nerve Block Anaesthesia for Ankle Fracture Surgery - an Exploratory Study: Is Rebound Pain a Problem?
The purpose of this exploratory study is to characterize the postoperative pain profile of patients undergoing operation with internal fixation of an ankle fracture under nerve block anaesthesia.
- Trial name
- NCT02100098
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Herlev Hospital
Ankle Fractures
Postoperative Aspirin and Ankle Fracture Healing
This study aims to identify if postoperative aspirin use leads to a delay in fracture healing. NSAIDs have long been avoided in the management of fractures, due to the belief that they may impair fracture healing.
- Trial name
- NCT03765619
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Fixation of Lateral Malleolus in Ankle Fracture Type A&B by Plate Versus Intramedullary Screw
Plate Versus Intramedullary Screw for Lateral Malleolus Fracture in Ankle Fracture Type A&B
The aim of this study is to compare the short term : Clinical, radiographic and functional outcome, and healing time and rate of complications between fixation of lateral malleolar fracture in Danis_Weber_A\&B fracture ankle by…
- Trial name
- NCT07447336
- Testing
- Fixation of lateral malleolar fracture in Danis_Weber_A&B fracture ankle by plate versus intramedullary screw fixation
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Sohag University
Ankle Fractures
Intramedullary Nailing Versus Plate Fixation of Ankle Fractures. A Prospective, Randomized Controlled Trial.
The purpose of this study is to make a survey of functional outcome, radiological outcome and complication rate after intramedullary nailing (IMN) and plate fixation of Weber B ankle fractures in elderly patients, and contribute…
- Trial name
- NCT03377205
- Testing
- Compression screws and neutralization plate, Acumed Fibular Rod System
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Muscle Atrophy, Muscle Weakness
Evaluating Muscle Function After Ankle Surgery
Patients who are forced to rest or reduce activity as a result of illness, injury, or surgery often experience resulting muscle weakness.
- Conditions
- Muscle Atrophy, Muscle Weakness, Fractures
- Trial name
- NCT00060970
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Foot Surgery, Ankle Surgery
Periarticular Injection Versus Popliteal Block
This study aims to determine the effectiveness and safety of two standard of care perioperative procedures for controlling pain following ankle and hindfoot osteotomy or fusion or ankle fracture repair.
- Trial name
- PvP (NCT04575688)
- Testing
- Exparel, Bupivicaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Campbell Clinic
Immobilization, Muscle Disuse Atrophy
Neuromuscular Electrical Stimulation During Immobilization Due to Ankle Fractures
Rationale: Situations such as fractures of the lower extremity can necessitate a prolonged period of immobilization in otherwise healthy individuals.
- Trial name
- ANKL-ES (NCT02469506)
- Testing
- Neuromuscular Electrical Stimulation (NMES)
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- Maastricht University Medical Center
Lateral Malleolus Fracture
A Study to Compare Two Different Managements After Ankle Surgery: Immediate and Delayed Weight-bearing.
The investigators will compare two types of rehabilitation in patients who undergo a surgery for treatment of malleolar fractures: immediate complete weight-bearing and delayed weight-bearing.
- Trial name
- NCT04429217
- Testing
- immediate post-operative complete weight-bearing after surgery, delayed weight-bearing for 6 weeks after surgery
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Foot Deformities, Acquired, Disorder of Joint of Foot
A Clinical Study of Outcomes in Foot and Ankle Bone Grafting Using map3® Cellular Allogeneic Bone Graft
This is a single arm pilot study in patients requiring surgical fusion in the foot or ankle. Patients will receive map3® Cellular Allogeneic Bone Graft containing donor matched stem cells.
- Conditions
- Foot Deformities, Acquired, Disorder of Joint of Foot, Fracture of Foot, Deformity of Bone
- Trial name
- NCT02161016
- Testing
- map3
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- RTI Surgical
Ankle Fractures
Fibular Nail vs Plate in Ankle Fractures
Randomised Controlled Trial to Compare the Efficacy of Fibular Nail Fixation vs Plate Fixation in Ankle Fracture Management
- Trial name
- NCT04303663
- Testing
- Fibular Plate, Fibular Nail
- Sponsor
- Chinese University of Hong Kong
Ankle Fractures, Syndesmotic Injury
Biodegradable Magnesium Screws for Unstable Ankle Fracture Surgery
Ankle fractures are among the most common injuries that need surgery. When the broken bones make the ankle unstable, surgeons usually fix them with metal screws and plates.
- Trial name
- NCT07693933
- Testing
- RemeOs Magnesium-Based Biodegradable Screw
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Massachusetts General Hospital
Deep Vein Thrombosis, Pulmonary Embolism
The D-KAF (Dalteparin in Knee-to-Ankle Fracture) Trial
It is known that patients who fracture their legs sometimes develop blood clots (known as deep vein thrombosis) in their legs. These clots may cause pain and swelling in the leg or they may detach and travel to the lungs…
- Trial name
- NCT00187408
- Testing
- Low Molecular Weight Heparin (dalteparin)
- Where
- 13 sites in Canada
- Volunteers
- 700 people
- Sponsor
- Sunnybrook Health Sciences Centre
Ankle Syndesmotic Injury Associated With Pott's Fracture
Correlation Between Ultrasound Findings Vs Intraoperative Findings in Syndesmotic Injury in Pott's Fracture Weber b and c
This study aims to assess and compare ultrasound findings, radiographic findings and intraoperative findings in cases of Pott's fractures weber types B and C to evaluate the accuracy of ultrasound in diagnosis of syndesmotic…
- Trial name
- NCT06945939
- Testing
- Fixation of Pott's fracture b and c
- Volunteers
- 20 people
- Sponsor
- Benha University
Ankle Fractures
Arthroscopic Assisted Open Reduction Internal Fixation Versus Open Reduction Internal Fixation in Ankle Fractures
The objective of this study is to compare the functional outcomes of patients with ankle fractures treated by Arthroscopic assisted Open Reduction Internal Fixation (AORIF) versus Open Reduction Internal Fixation (ORIF).
- Trial name
- NCT03084263
- Testing
- Arthroscopic Assisted Open Reduction Internal Fixation, Open Reduction Internal Fixation
- Where
- United States
- Sponsor
- Corewell Health West