Clinical trials: Ankle Sprain, open to volunteers
Chronic Ankle Instability
Pelvic Parameters in Males With and Without Ankle Instability
This study aims to investigate the relationship between pelvic alignment and ankle stability in male athletes with and without a history of ankle sprain.
- Trial name
- NCT07594210
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ahmed Korany Abdallah Ahmed
Ankle Sprains, Patellofemoral Pain Syndrome
Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders
Lateral ankle sprain (LAS) and patellofemoral pain syndrome (PFPS) are common musculoskeletal conditions associated with postural instability.
- Trial name
- LAS-PFPS (NCT07508163)
- Testing
- diagnosis of APSI, MLSI, OASI
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ankle Sprain, Ankle Sprain Strain
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Amateur Athletes With Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after…
- Conditions
- Ankle Sprain, Ankle Sprain Strain, Ankle Inversion Sprain
- Trial name
- NCT07760233
- Testing
- Postural Stabilization Training, Vestibulo-Ocular Reflex Exercise in addition to Postural Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Bahçeşehir University
Ankle Sprains
A Mobile Recovery Guidance App for Children and Young Adults With Acute Ankle Inversion Injuries
Ankle sprains are the most common musculoskeletal complaint of children presenting to the emergency department (ED). Healing can often be protracted, leading to prolonged pain, missed school and work, and delayed return to a…
- Trial name
- SPRAIN (NCT05785533)
- Testing
- Smartphone App, Standard of Care
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Naveen Poonai
Ankle Sprain
Semiconductor Embedded Socks for Ankle Sprains
The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains. The main questions it aims to answer are: 1.
- Trial name
- NCT07025733
- Testing
- Semiconductor Embedded Sock, Control Compression Sock
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Ankle Sprain
NMES With PNF for Ankle Sprain Rehabilitation
Ankle sprains are one of the most common sports injuries. In some people, they can lead to chronic ankle problems that affect daily life and sports performance.
- Trial name
- NCT07190599
- Testing
- Proprioceptive neuromuscular facilitation (PNF) with neuromuscular electrical stimulation (NMES), Proprioceptive neuromuscular facilitation (PNF) only
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fooyin University
Ankle Sprains, Instability, Joint
Arthroscopic Versus Open Brostrom for Ankle Instability
Background: Ankle sprains are among the most prevalent lesions in primary care. A substantial number of these ligament lesions will develop ankle instability and require a surgical procedure.
- Conditions
- Ankle Sprains, Instability, Joint, Ligament Injury, Surgery
- Trial name
- NCT03643926
- Testing
- Arthroscopic Brostrom, Open Brostrom
- Where
- 2 sites in Brazil
- Volunteers
- 98 people
- Sponsor
- Federal University of São Paulo
Hamstring Muscle Strain
Effects Of Criteria Versus Time-Based Rehabilitation On Return To Play In Football Players
This randomized controlled trial compares criteria-based rehabilitation (CBR) with time-based rehabilitation (TBR) for football players aged 18-35 with ACL reconstruction, hamstring strain, or ankle sprain.
- Trial name
- NCT07815340
- Testing
- Experimental: Criteria based, Active comparator: Time based rehabilitation
- Where
- 2 sites in Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Musculoskeletal Injury, Pediatrics
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
The TOP-MAP pilot trial has multiple goals. The first goal of this pilot clinical trial is to find out if it will be possible to carry out a study at multiple pediatric emergency department sites (Peds ED) comparing Non-Steroidal…
- Conditions
- Musculoskeletal Injury, Pediatrics, Sprain and Strain of Ankle, Sprain Knee
- Trial name
- TOP-MAP (NCT07145645)
- Testing
- Voltaren Topical Gel, Ibuprofen Oral Suspension 100 mg/5mL, ORA-Blend Oral Suspension
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Ankle Sprain
the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain
Investigators recruited 208 patients with acute ankle sprain who were from the Rehabilitation Department of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2026 to November 2028.
- Trial name
- NCT07405281
- Testing
- hyperbaric oxygen therapy, non Hyperbaric Oxygen Therapy
- Volunteers
- 208 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ankle Sprain, Lateral Ankle Sprain
Dynamic Neuromuscular Stability Exercises With and Without Rhythmic Auditory Stimulation in Lateral Ankle Sprain
To examine the effects of Dynamic Neuromuscular Stability exercises with and without Rhythmic Auditory Stimulation on balance, proprioception, and functional performance in badminton players with lateral ankle sprain.
- Conditions
- Ankle Sprain, Lateral Ankle Sprain, Lateral Ankle Instability, Dynamic Neuromuscular Stabilization (DNS)
- Trial name
- DNS (NCT07726810)
- Testing
- Dynamic Neuromuscular Stabilization with Rhythmic Auditory Stimulation, Dynamic Neuromuscular Stabilization Alone
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Ankle Sprain, Ankle (Ligaments); Instability (Old Injury)
Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy
Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence…
- Conditions
- Ankle Sprain, Ankle (Ligaments); Instability (Old Injury), Pain Management, ERAS
- Trial name
- NCT07460310
- Testing
- Total intravenous anesthesia combined with peripheral nerve block (TIVA + PNB) group, General anesthesia combined with peripheral nerve block (GA + PNB) group, Spinal anesthesia
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Ankle Instability, CAI, Ankle Sprain
Ankle vs. Hip vs. Combined Strengthening in Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition that can develop after a lateral ankle sprain. Up to 40% of people who sprain their ankle experience a recurrence within a year, and as many as 30% develop persistent symptoms…
- Trial name
- SHAC (NCT07606534)
- Testing
- Isometric Ankle Strengthening Program, Hip Strengthening, Combined Isometric Ankle and Hip Strengthening Program
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- University of Liege
Ankle Sprain
Computed Tomography With Stress Maneuvers for Evaluation of Distal Tibiofibular Syndesmosis Instability (CTMETS)
The main aim of this study was to investigate which strategy can diagnose more accurately syndesmotic instability among an existing index test (ankle CT in neutral position) and two new add-on index tests (ankle CT in a stress…
- Trial name
- CTMETS (NCT04095598)
- Testing
- Comparative Ankle Tomography with Stress Maneuvers
- Where
- Brazil
- Volunteers
- 133 people
- Sponsor
- Hospital Israelita Albert Einstein
Ankle Sprain
Surgical Management of Lateral Ankle Instability: Modified Broström-Gould Versus Arthroscopic Allograft Reconstruction of the Anterior Talofibular and Calcaneofibular Ligaments.
Primary Objective: To clarify whether arthroscopic reconstruction with allograft provides tangible benefits over the modified open Broström-Gould technique, or if both are equivalent in efficacy and safety.
- Trial name
- NCT07200271
- Testing
- Arthroscopic reconstruction surgery, Open surgery
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Francisco de Vitoria
Ankle Sprains
Interest of Ultrasound in the Diagnosis of Severity of Lateral Ankle Sprain
Ankle sprain is a frequent and widely trivialized trauma. Misdiagnosed or poorly treated, it can recur and thus develop into chronic ankle instability.
- Trial name
- NCT04846712
- Testing
- Collect data of medical record
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Ankle Sprains, Hypermobility Syndrome
Comparison of MBR + Suture Tape, MBR, and Anatomic Reconstruction for CLAI in GJL Cases: A Prospective Cohort Study
GJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. BPR with suture tape augmentation and anatomic reconstruction may provide more strength and stability.
- Trial name
- NCT05698446
- Testing
- Modified Broström + Suture tape augmentation operation, Anatomic reconstruction operation, Open Modified Broström procedure
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Peking University Third Hospital
Ankle Sprains, Ankle Sprain Strain
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after…
- Conditions
- Ankle Sprains, Ankle Sprain Strain, Ankle Inversion Sprain
- Trial name
- NCT07728526
- Testing
- Postural Stabilization Training, Vestibulo-Ocular Reflex Exercise in addition to Postural Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bahçeşehir University
Ankle Sprain
Functional Recovery After a Recent Lateral Ankle Sprain With Early Initiation of Rehabilitation: Changes in the Ankle-GO Score and Its Association With Return to Sport and Recurrent Sprains.
Lateral ankle sprains are common musculoskeletal injuries, particularly among young adults and athletes. Although recovery is often favorable, lateral ankle sprains may be associated with persistent pain, chronic ankle…
- Trial name
- ASGO (NCT07917273)
- Testing
- Ankle-GO test and questionnaires
- Where
- France
- Volunteers
- 76 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Chronic Ankle Instability, CAI
MOTOR TRAINING VERSUS MOTOR COGNITIVE TRAINING IN ATHLETES WITH CHRONIC ANKLE INSTABILITY
This study aims to evaluate the effect of one-leg balance activity (OLBA) combined with visual feedback using BlazePod™ as a dual motor-cognitive rehabilitation task in basketball players with Chronic Ankle Instability (CAI).
- Trial name
- NCT07078916
- Testing
- Motor-Cognitive Training Group (OLBA + BlazePod™), Motor Training Group (OLBA Only)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University