Clinical trials: Ankylosing Spondylitis, open to volunteers
Osteoarthritis, Ankylosing Spondylitis
15-Hydroxyprostaglandin Dehydrogenase in Osteoarthritis and Ankylosing Spondylitis
To evaluate serum and synovial fluid 15-PGDH levels in patients with osteoarthritis and ankylosing spondylitis and determine their associations with clinical and musculoskeletal ultrasound features.
- Trial name
- HPGD-OA-AS-US (NCT07751263)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ankylosing Spondylitis (AS), Irisin
The Effect of Exercise on Serum Irisin Levels and Clinical Parameters in Patients With Axial Spondyloarthritis.
This study aimed to investigate the effects of high-intensity intermittent exercise and moderate-intensity continuous exercise on serum irisin levels, disease activity, functional status, and quality of life in patients with…
- Trial name
- NCT07327073
- Testing
- High-Intensity Interval Training, Moderate-Intensity Continuous Exercise, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Axial Spondyloarthritis, Axial Spondyloarthritis (AxSpA)
A LONGITUDINAL OBSERVATIONAL STUDY to EVALUATE the EFFICACY of MOVEMENT and IMPLEMENT CONCRETE MOVEMENT RECOMMENDATIONS with the HELP of MOBILITY TRACKING with SMARTWATCHES in SUBJECTS with AXIAL SPONDYLOARTHRITIS
Axial spondyloarthritis (axSpa) is a chronic inflammatoric autoimmune disease of the back with a prevalence around 1,4% (1) . In patients decreased function and decreased quality of life as well as chronic pain are strong burdens…
- Conditions
- Axial Spondyloarthritis, Axial Spondyloarthritis (AxSpA), Axial Spondylarthritis (r-axSpA), Axial Spondyloarthopathy
- Trial name
- SPARTAKUS (NCT06807853)
- Testing
- Smartwatch
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Bonn
Ankylosing Spondylitis
A Study of Comparing Overall Improvement of Patients With Spondyloarthritis Treated With Jitongning Tablets and Placebo
The goal of this clinical trial is evaluating the efficacy and safety of Jitongning tablets in participant population. The main questions it aims to answer are: Based on the proportion of participants who achieved improvement in…
- Trial name
- NCT06000956
- Testing
- Jitongning tablets, a simulated agent of Jitongning tablets
- Where
- 10 sites in China
- Volunteers
- 408 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Ankylosing Spondylitis (AS)
Phase Ia Study of MST-931 in Healthy Adult Subjects
A Phase 1a, randomized, double-blind study of MST-931 in healthy participants. The purpose of this research is to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of a single…
- Trial name
- NCT07903493
- Testing
- MST-931
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mabsoft Therapeutics (Shanghai) Co., Ltd.
Rheumatoid Arthritis (RA, Ankylosing Spondylitis
Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases
Rheumatic diseases are chronic inflammatory conditions that can lead to long-term tissue damage and increased cardiovascular and metabolic risk.
- Conditions
- Rheumatoid Arthritis (RA, Ankylosing Spondylitis, Psoriatic Arthritis, Reactive Arthritis (ReA)
- Trial name
- NCT07329556
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bursa City Hospital
Spondyloarthropathies, Ankylosing Spondylitis
Faecal Analyses in Spondyloarthritis Therapy
This study evaluates the intestinal microbiome and disease activity in patients with spondyloarthropathies receiving immunosuppressive therapy.
- Trial name
- FAST (NCT03839862)
- Testing
- TNF-inhibition
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Ankylosing Spondylitis (AS)
The Effect of Laughter Yoga on Patients With Ankylosing Spondylitis
This study will be conducted to evaluate the effects of laughter yoga on disease activity, pain, functional status, depression/anxiety/stress, and quality of life in ankylosing spondylitis patients.
- Trial name
- NCT07128264
- Testing
- Laughter Yoga
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Arthritis, Rheumatoid, Arthritis, Psoriatic
IMPACT - AndHealth Autoimmune Research Registry
This is a patient research registry aimed at evaluating the effectiveness of a comprehensive, root-cause medical approach ("AndHealth program") for autoimmune disorders.
- Conditions
- Arthritis, Rheumatoid, Arthritis, Psoriatic, Psoriasis, Ankylosing Spondylitis
- Trial name
- NCT05883371
- Testing
- Root-cause autoimmune treatment program
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- AndHealth
Ankylosing Spondylitis
Safety and Efficacy of Allogeneic Bone Marrow MSCs in Ankylosing Spondylitis
The goal of this clinical trial is to learn if allogeneic human bone marrow-derived mesenchymal stem cells (CG-BM1) are safe and show preliminary efficacy in treating patients with ankylosing spondylitis (AS).
- Trial name
- NCT07632599
- Testing
- IV administration of CG-BM1, CG-BM1
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Rheumatoid Arthritis, Ankylosing Spondylitis
Safety and Efficacy of Capsule FMT in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases
PURPOSE: The main purpose is to explore clinical efficacy and safety associated with capsule FMT (cFMT) performed in newly diagnosed, untreated patients with rheumatic and gastrointestinal chronic inflammatory diseases (CIDs).
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Crohn Disease
- Trial name
- FRONT (NCT04924270)
- Testing
- Faecal microbiota transplantation
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Odense University Hospital
Radiographic Axial Spondyloarthritis
A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)
Researchers are looking for new ways to treat radiographic axial spondyloarthritis (r-axSpA). R-axSpA is a type of arthritis that causes pain, stiffness, and inflammation (swelling) in the spine and joints in the pelvis (hip…
- Trial name
- NCT07133633
- Testing
- Tulisokibart
- Where
- 107 sites in United States, Brazil and 12 more
- Volunteers
- 315 people
- Sponsor
- Merck Sharp & Dohme LLC
Ankylosing Spondylitis
A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis
This study employs a randomized controlled trial methodology to systematically evaluate the efficacy and safety of a modified acupotomy technique in the treatment of ankylosing spondylitis.
- Trial name
- UGA-AS RCT (NCT07578220)
- Testing
- Ultrasound-guided acupotomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China-Japan Friendship Hospital
Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS)
An Investigation of the Effect of Smartphone Usage Levels on Cervical Posture, Tongue Pressure, Balance, and Neck Disability in Individuals With Rheumatoid Arthritis and Ankylosing Spondylitis
The purpose of this cross-sectional and comparative study is to investigate the impact of smartphone addiction on the cervical posture, musculoskeletal system, balance, and tongue pressure in individuals diagnosed with Rheumatoid…
- Conditions
- Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS), Forward Head Posture
- Trial name
- NCT07627542
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Merve Şahin
Ankylosing Spondylitis
SLAMF1 Gene Expression in Ankylosing Spondylitis
This cross-sectional study aims to evaluate SLAMF1 gene expression levels in patients with ankylosing spondylitis compared with healthy controls.
- Trial name
- NCT07907913
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ankylosing Spondylitis, AS
Expression of Tim-3 on Neutrophils in Ankylosing Spondylitis
1. To investigate the expression of Tim-3 on neutrophils in ankylosing spondylitis patients and its correlation with disease activity and inflammatory markers. 2.
- Conditions
- Ankylosing Spondylitis, AS, Tim3
- Trial name
- NCT07383805
- Where
- Egypt
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rheumatic Disease
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
The purpose of this study is to assess the incidence of rheumatologic flares, changes in pain scores (VAS), changes in functional outcomes (PROMIS), wound complications, surgical site infections, and return trips to the operating…
- Trial name
- NCT07138898
- Testing
- Methotrexate, Sulfasalazine, Hydroxychloroquine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
Rheumatic Diseases, Adult Onset Still Disease
Rheumatology Patient Registry and Biorepository
To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.
- Conditions
- Rheumatic Diseases, Adult Onset Still Disease, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT04402086
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Yale University
Ankylosing Spondylitis, Rheumatic Arthritis
Biomarkers in Inflammatory Rheumatic Diseases Diagnosis
Ankylosing spondylitis (AS), Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) are three diseases where early diagnosis remains a major challenge.
- Conditions
- Ankylosing Spondylitis, Rheumatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- BIRDD (NCT06778343)
- Where
- Portugal
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Spondyloarthropathy
Identification of Serum Level of Glutathione Peroxidase 4
Analysis of the level of glutathione peroxidase 4 (GPX4) in ankylosing spondylitis and axial psoriatic arthritis patients. The association of glutathione peroxidase 4 (GPX4) with disease activity and severity in ankylosing…
- Trial name
- NCT06554392
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Assiut University