Clinical trials: Anophthalmia
Advanced Cancers (Breast, Ovarian, mCRPC, Pancreatic Ductal Adenocarcinoma (PDAC), Brain Mets) With Specific Mutations (Homologous Recombination Deficiency)
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Open label, multi-centre, Phase Ia/b adaptive design study with an initial 2-stage Dose Escalation Phase followed by a Dose Expansion Phase.
- Trial name
- NCT06458712
- Testing
- DSB2455
- Where
- 21 sites in United States, France and 3 more
- Volunteers
- 180 people
- Sponsor
- Duke Street Bio Ltd
Orbital Atrophy
Autologous Fat Grafting With PRP (Platelet Rich Plasma) to Anophthalmic Sockets
After people lose an eye, for whatever reason, they often experience fat atrophy of the tissues in the orbit. This leads to a sunken appearance that is often not correctable by a cosmetic shell prosthesis.
- Trial name
- NCT01712555
- Testing
- autologous fat grafting with PRP to anophthalmic orbits
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Fox, Donald Munro, M.D., P.C.