Clinical trials: Anorectal Disorder
Anal Fistula, Crohn's Disease
Treatment of Crohn's Fistula Using a Porcine Intestine Submucosa Graft
Healing anal fistulas in Crohn's patients with an anal fistula plug.
- Trial name
- SurgiSIS AFP (NCT00610207)
- Testing
- Surgisis Biodesign Anal Fistula Plug (SurgiSIS AFP)
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Cook Group Incorporated
Fecal Incontinence
Treatment of Patients With Fecal Incontinence
The purpose of this study is to determine if a behavioral treatment method called biofeedback will reduce the frequency of episodes of leakage of fecal material in patient suffering from fecal incontinence.
- Trial name
- NCT00292318
- Testing
- Biofeedback Therapy for Fecal Incontinence: A Randomized Control Study, control group
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- US Department of Veterans Affairs
Anterior Resection Syndrome, Bowel Dysfunction
Studies in Patients With Low Anterior Resection Syndrome (LARS)
Colorectal Cancer is the commonest cancer diagnosed for both genders combined in Hong Kong. In 2015 16.6% of all new cancer cases registered on the Hong Kong registry were cancer of colon and rectum.
- Trial name
- NCT03885999
- Testing
- Fecobionics
- Where
- Hong Kong
- Volunteers
- 12 people
- Sponsor
- Giome
Constipation, Fecal Incontinence
Treating Anorectal Dysfunction in MS
The investigators seek to test whether incorporating the scheduled dosing of a bisacodyl 10 mg rectal suppository every other day improves bowel-related symptoms in patients with multiple sclerosis.
- Conditions
- Constipation, Fecal Incontinence, Multiple Sclerosis
- Trial name
- NCT02609607
- Testing
- Bisacodyl
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- David Levinthal
Anorectal Disorders
Anal Resting Pressure After Bidet, Compared to Sitz Bath
Sitz bath is conventional and empirical remedy and commonly recommended for non-operative treatment of various anal diseases. However, as there was no substitute for sitz bath until now, the patients have to accept the…
- Trial name
- Bidet(2) (NCT02244840)
- Testing
- Electronic bidet, Sitz bath
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Anal Fistula
A Randomized Clinical Trial Comparing Surgisis AFP to Advancement Flap for the Repair of Anal Fistulas
The purpose of this study is to determine whether the Surgisis anal fistula plug is just as effective in healing anal fistulas as compared to the advancement flap procedure.
- Trial name
- Surgisis® AFP (NCT00545441)
- Testing
- Surgisis Biodesign Anal Fistula Plug (Surgisis® AFP), Flap
- Where
- 6 sites in Germany
- Volunteers
- 86 people
- Sponsor
- Cook Group Incorporated
Anorectal Disorder
Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery
The purpose of the study is to evaluate whether being randomized to an aggressive postoperative non-narcotic pain regimen that treats pain from multiple different pathways may decrease postoperative pain levels, decrease…
- Trial name
- NCT03738904
- Testing
- ERAS, Standard of care
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Anal Cancer, Rectal Cancer
A Phase 2 Study of Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal
This is a single arm Phase 2 study. Stage 1 and 2 of the study are monotherapy evaluations of ADXS11-001 in 31 and 24 participants, respectively with persistent/recurrent, loco-regional or metastatic squamous cell carcinoma…
- Trial name
- NCT02399813
- Testing
- Axalimogene filolisbac
- Where
- 10 sites in United States
- Volunteers
- 36 people
- Sponsor
- Advaxis, Inc.
Anorectal Fistulas
A Prospective, Multi-center, Observational Study of the Use of Permacol™ Collagen Paste to Treat Anorectal Fistulas
This will be a prospective, multi-center, post-market, single arm observational study to collect clinical outcome data on the use of Permacol™ Collagen Paste in the treatment of anorectal fistulas.
- Trial name
- NCT01624350
- Testing
- Permacol collagen paste
- Where
- 10 sites in Denmark, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG