Clinical trials: Antenatal Corticosteroids
Oxidative Stress
Prenatal Corticosteroids and Antioxidants in Preterm Infants
Premature infants are highly susceptible to oxidative stress because of the immaturity of their antioxidant defense system. The use of prenatal glucocorticosteroids administered to the mother improves respiratory function and…
- Trial name
- RESOX (NCT00791687)
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Fundacion Para La Investigacion Hospital La Fe
Adrenocortical Carcinoma, Localized Resectable Neuroblastoma
Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging
This natural history study is collecting health information about infants with adrenal masses found on prenatal and/or neonatal imaging.
- Conditions
- Adrenocortical Carcinoma, Localized Resectable Neuroblastoma, Precancerous Condition
- Trial name
- NCT00445718
- Testing
- computed tomography, 3-Tesla magnetic resonance imaging, Abdominal Sonogram
- Where
- 45 sites in United States, Australia and 1 more
- Volunteers
- 97 people
- Sponsor
- Children's Oncology Group
Neonatal Distress
Caesarean and Corticotherapy
Comparison of two randomized group : caesarean section planned at 38 weeks after 2 antenatal injections of 12 mg of betamethasone 48 h before. caesarean section planned at 39 weeks without corticosteroid.
- Trial name
- NCT00446953
- Testing
- betamethasone
- Where
- 5 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Pregnancy Preterm, Glycemic Control
Metformin to Treat Corticosteroids-induced Hyperglycemia
Antenatal corticosteroids, particularly, betamethasone is routinely administered to pregnant women at risk for preterm delivery to improve neonatal outcomes.
- Conditions
- Pregnancy Preterm, Glycemic Control, Corticosteroids Induced Hyperglycemia
- Trial name
- NCT04332393
- Testing
- Metformin
- Where
- 4 sites in Israel
- Volunteers
- 187 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Premature Birth, Neonatal Hypoglycemia
Higher-Dose Dexamethasone Improves Breathing and Shortens NICU Stay in Preterm Babies
The goal of this observational study was to compare two doses of dexamethasone given to pregnant women at risk of preterm birth. Dexamethasone is a medicine used before birth to help a baby's lungs mature.
- Conditions
- Premature Birth, Neonatal Hypoglycemia, Maternal Infection During Pregnancy, Neurodevelopmental Disorder of Foetus
- Trial name
- NCT07765329
- Testing
- Dexamethasone 12 mg Every 12 Hours, Dexamethasone 6 mg Every 12 Hours
- Where
- Indonesia
- Volunteers
- 200 people
- Sponsor
- Stella Maris Women and Children Hospital
Twin Pregnancy, Antepartum Condition or Complication
Effects of ACS in Twin With LPB: Study Protocol for a RCT
This study will be the first study that evaluates the effectiveness of antenatal corticosteroid (ACS) in late preterm twin neonates.
- Trial name
- NCT03547791
- Testing
- Betamethason Sodium Phosphate, Normal saline
- Where
- South Korea
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hyaline Membrane Disease, Transient Tachypnea
Antenatal Corticoid Therapy for Late Preterm Babies
This study aims to determine the effectiveness of antenatal corticosteroid therapy in late preterm babies. The investigators hypothesis is corticoid accelerates fetal lung maturation even after 34 weeks and reduces risk of…
- Trial name
- ACTLPT (NCT00675246)
- Testing
- Betamethasone
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Late Preterm
Effect of Antenatal Corticosteroids in Late Preterm
To test the effect on premature infants of a one-time course of betamethasone administered in weeks 34-36 of gestation.
- Trial name
- NCT01710384
- Testing
- betamethasone
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Antenatal Corticosteroids
Effect of Antenatal Corticosteroids on Neonatal Hypoglycemia
Comparing the incidence of neonatal hypoglycemia in infants born to mothers who received antenatal corticosteroids to those who did not.
- Trial name
- NCT06716918
- Testing
- Corticosteroid Injection
- Where
- Egypt
- Volunteers
- 188 people
- Sponsor
- Assiut University
Preterm Labor, Premature Birth
Effectiveness of ACS in Extreme Preemies
This is a randomized prospective clinical study that will evaluate the effects of antenatal corticosteroid administration (ACS) vs.
- Trial name
- NCT02351310
- Testing
- Betamethasone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Preterm Birth, Complication of Prematurity
Single Dose Antenatal Corticosteroids (SNACS) for Women at Risk of Preterm Birth
Antenatal corticosteroids (ACS) reduce the risks of neonatal death and morbidities, such as respiratory distress syndrome, in preterm infants.
- Conditions
- Preterm Birth, Complication of Prematurity, Obstetric Labor, Premature, Obstetric Labor Complications
- Trial name
- SNACS Pilot (NCT04494529)
- Testing
- 24 mg betamethasone
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Preterm Pregnancy, Antenatal Corticosteroid
The Effect Of Antenatal Corticosteroids On Early And Late Perinatal Outcomes
In this study, the investigators aims to evaluate whether antenatal corticosteroid administration to women likely to give birth in the late preterm period will reduce early and late neonatal complications and contribute to the…
- Conditions
- Preterm Pregnancy, Antenatal Corticosteroid, Perinatal Problems
- Trial name
- NCT06164080
- Testing
- participants receiving Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Acute Respiratory Distress Syndrome, Respiratory Distress Syndrome, Acute
Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS
1. A predictive model for NARDS was established based on perinatal risk factors. Multivariate Logistic regression analysis was used to screen the independent prenatal risk factors for NARDS.
- Trial name
- NCT06188195
- Testing
- Dexamethasone
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Neonatal Respiratory Distress Syndrome
Effect of Antenatal Corticosteroids on Neonatal Morbidity.
It will be a randomized controlled trial. There will be two study groups. Study group 1 will be given dexamethasone while study group 2 will be given betamethasone. The control group will be given placebo.
- Trial name
- NCT03446937
- Testing
- Dexamethasone Sodium Phosphate Injection, Betamethasone Sodium Phosphate Injection (Medication), Water for injection
- Where
- Nigeria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University Teaching Hospital
Diabetes Mellitus, Type 2, Preterm Birth
Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes
There is a fundamental gap in understanding the maternal and neonatal effects of antenatal corticosteroid (ACS) administration in women with threatened preterm birth (PTB) who have diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Preterm Birth, Pregnancy, High Risk, Diabetes, Gestational
- Trial name
- NCT04542148
- Testing
- Sliding Scale Insulin, Up-Titration of Home Insulin, Continuous Insulin Infusion
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Alabama at Birmingham