Clinical trials: Antenatal Depression
Anxiety, Pregnancy Related
MoodUP in Improving Psychological Outcomes Among Perinatal Women
Dramatic physiological, psychological, and social changes during the antenatal period may significantly affect a woman's psychosocial and physical conditions, thereby resulting in stress, anxiety, and depressive symptoms.
- Conditions
- Anxiety, Pregnancy Related, Perinatal Depression, Prenatal Stress
- Trial name
- NCT03970057
- Testing
- Internet-based Cognitive Behavioural Therapy, Usual Care
- Where
- Singapore
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Prenatal Depression, Ketamine
Effect of Low-dose Esketamine on Maternal Depression at 3 Years After Childbirth
Postpartum depression refers to the depression after childbirth, which is a common mental disorder in women. The pathogenesis of postpartum depression is not fully understood, and may be related to a variety of factors.
- Conditions
- Prenatal Depression, Ketamine, Postpartum Depression
- Trial name
- NCT05698394
- Testing
- Esketamine
- Where
- 4 sites in China
- Volunteers
- 364 people
- Sponsor
- Peking University First Hospital
Maternal Psychological Distress, Postpartum Depression
Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy
The study is a pilot randomized control trial of a validated intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, developed to reduce risk for postpartum depression.
- Conditions
- Maternal Psychological Distress, Postpartum Depression, Prenatal Stress
- Trial name
- NCT03809572
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cerebral Palsy, Infant Development
Relationship Between Prenatal Maternal Distress and the Quality of General Movements at 3 Months
Depression and anxiety symptoms are common during pregnancy which may disturb the intrauterine environment by affecting the mother's physiological responses to stress, and ultimately impair fetal and postnatal development.
- Conditions
- Cerebral Palsy, Infant Development, Maternal Distress
- Trial name
- NCT05694676
- Testing
- Assessment of the quality of Genaral Movements (GMs), State-Trait Anxiety Inventory-Trait, (STAI-T), Beck Depression Inventory, (BDI)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karamanoğlu Mehmetbey University
Major Depressive Disorder in Pregnancy
Cytokines, PUFA Tissue Concentrations and Treatment Selection in Antenatal MDD
For a number of reasons women with major depressive disorder often discontinue conventional antidepressants when they become pregnant and prefer not to take them when depressive illness develops in the course of pregnancy.
- Trial name
- NCT03101540
- Testing
- Omega-3 PUFA supplementation
- Volunteers
- 27 people
- Sponsor
- William Coryell
Depression / Major Depressive Disorder, Antenatal Depression
Stronger Together: Antenatal Depressive Symptoms - Prevalence and Digital Treatment
The main objective of the current research project is to evaluate the usability, satisfaction of the antenatal iCBT program including telephone coaching for antenatal and postnatal depressive symptoms and collect nationally…
- Trial name
- NCT07639164
- Testing
- Digitalized CBT with phone coaching
- Where
- Finland
- Volunteers
- 1,000 people
- Sponsor
- University of Turku
Stress, Anxiety
Mindfulness in High Risk Pregnancies
Anxiety, depression and stress are common during pregnancy. These have been found to negatively impact mother and child outcomes.
- Conditions
- Stress, Anxiety, Depression, Mindfulness
- Trial name
- NCT04496115
- Testing
- Mindfulness
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Perinatal Mental Health, Gestational Weight Gain
Healthy Adaptation to Pregnancy, Postpartum and Parenthood
Healthy Adaptation to Pregnancy, Postpartum and Parenthood (HAP3) The HAP3 study is evaluating a new digital support program for pregnant women and their partners.
- Conditions
- Perinatal Mental Health, Gestational Weight Gain, Postpartum Weight Retention, Child Development
- Trial name
- HAP3 (NCT07837193)
- Testing
- HAP3 Family App
- Where
- Belgium
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Perinatal Depression, Ketamine
Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Postpartum depression is common in mothers early after childbirth and produces harmful effects not only on mothers, but also on infants and young children.
- Conditions
- Perinatal Depression, Ketamine, Cesarean Delivery, Postpartum Depression
- Trial name
- NCT03336541
- Testing
- Ketamine
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University First Hospital
Anxiety Disorders Generalized, Depression
Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners
This pilot study engaged pregnant couples experiencing elevated symptoms of maternal anxiety or depression with an existing online psychoeducation intervention, the Online Mothers and Babies Course (eMB).
- Trial name
- NCT05867680
- Testing
- Online Mothers and Babies Course (eMB)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Missouri-Columbia
Pregnancy Related, Stress, Psychological
The Stony Brook University Calm-Mom Study
The present trial will evaluate the feasibility, acceptability and preliminary efficacy of 2 different internet-delivered programs for prenatal maternal stress.
- Conditions
- Pregnancy Related, Stress, Psychological, Anxiety, Perinatal Depression
- Trial name
- NCT04018625
- Testing
- SMART Mom, Mama Support
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Stony Brook University