Clinical trials: Anterior Cervical Spine Surgery
Myelopathy
Comparing Allograft to Autograft Bone in ACDF Surgeries
Anterior cervical discectomy and fusion (ACDF) is a surgery performed from the front of the neck in which damaged discs are removed and a bone graft is inserted into the space to allow the bone to grow together to set up a bridge…
- Trial name
- NCT03518164
- Testing
- Allograft
- Sponsor
- Rutgers, The State University of New Jersey
Cervical Vertebral Disc Degeneration, Intervertebral Disc Displacement
Cervical Movement Control Before and After Anterior Cervical Discectomy and Fusion
Degenerative cervical disc disease can cause neck pain, nerve symptoms, dizziness, and problems with balance and head movement control.
- Trial name
- MOVE-ACDF (NCT07425613)
- Testing
- Anterior Cervical Discectomy and Fusion
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University of Ljubljana
Dysphagia
Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal)
This prospective, randomized, double blind, controlled study evaluates the effect of a single dose of perioperative IV steroid versus saline on swallowing after anterior cervical spine surgery
- Trial name
- NCT03711474
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Postextubation Stridor
Airway Ultrasound as a Predictor for Postextubation Stridor in Anterior Cervical Spine Surgery
literature on use of the ultrasound (US) in extubation decisions in cervical spine surgery is scarce.The aim of this study will be to evaluate the utility of US as an aid for decision making for extubation in elective cervical…
- Trial name
- NCT03764904
- Testing
- Airway Ultrasound
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Cervical Spine Fusion
Measuring Dysphagia After ACDF Surgery Through A Novel Wearable Sensor
The purpose of this study is to assess the function and reliability of a noninvasive, skin-like electronic sensor. The investigators hypothesize that this skin sensor will address an unmet need to wirelessly and noninvasively…
- Trial name
- NCT04921800
- Testing
- Anterior Cervical Discectomy & Fusion, Application of ADAM mechanoacoustic skin sensor
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Northwestern University
Radiculopathy, Cervical, Myelopathy
A Study of Korean Society of Spine Surgery on the Outcomes of Anterior Cervical Discectomy and Fusion
The purpose of this study is firstly to determine the efficacy of cervical plate for anterior cervical discectomy and fusion using cervical cage, and secondly to investigate the determining factors for surgical outcomes.
- Trial name
- NCT01911013
- Testing
- anterior cervical discectomy and fusion, Cage and Plate, Cage alone
- Where
- 31 sites in South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital
Symptomatic Cervical Disc Disease
Safety and Efficacy Study Comparing ProDisc-C to ACDF Surgery to Treat SCDD
The objective of this clinical investigation is to compare the safety and effectiveness of ProDisc-C to anterior cervical discectomy and fusion (ACDF) surgery in the treatment of symptomatic cervical disc disease (SCDD).
- Trial name
- NCT00291018
- Testing
- Total Disc Replacement, ACDF
- Volunteers
- 368 people
- Sponsor
- Synthes USA HQ, Inc.
Anesthesia, Local
Preoperative Block for Anterior Cervical Spine Surgery
The purpose of this clinical trial study is to compare the analgesic effects of ultrasound-guided intermediate cervical plexus block Versus cervical erector spinae block in patients undergoing anterior cervical spine surgery.
- Trial name
- ESPB/ICPB (NCT06867510)
- Testing
- Block for Anterior Cervical Spine Surgery
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Vocal Cord Dysfunction
Ultrasound Prediction For Vocal Cord Dysfunction In Patients Scheduled For Anterior Cervical Spine Surgeries
Anterior cervical discectomy and fusion (ACDF) is a highly effective and safe method for spinal cord and cervical root decompression.
- Trial name
- NCT04140799
- Testing
- vocal cord ultrasonography
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Stress
Intermediate Cervical Plexus Block on Stress Response
The aim of the present study is to investigate the effect of Bilateral Ultrasound-Guided intermediate cervical plexus Block combined with general anesthesia on the stress and inflammatory response in patients undergoing anterior…
- Trial name
- NCT06064214
- Testing
- u/s guided intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patients Receiving Anterior Cervical Spine Surgery
Swallowing Motor Function After Cervical Spine Surgery With Anterior Approach
Dysphagia is a well-known complication following anterior cervical spine surgery. However, which muscle at oropharyngeal region weakness and the recovery course of these patients are still unknown.
- Trial name
- NCT03891940
- Testing
- patients recieving anterior cervical spine surgery
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Wound Heal
Platysma Incision Cosmesis
The anterior cervical fusion and decompression (ACDF) surgery provides direct access to symptomatic areas of the cervical spine.
- Trial name
- NCT03338608
- Testing
- Anterior Cervical Decompression and Fusion, Vertical Platysma Incision, Transverse Platysma Incision
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Dysphagia, Cervical Spinal Cord Injury
Dysphagia After Anterior Cervical Spine Surgery
The purpose of this research project is to investigate the incidence of impaired swallowing (dysphagia) after anterior cervical spine surgery (ACSS) and to study the long-term effect of dysphagia on nutritional status 12 ± 3…
- Trial name
- NCT04855838
- Testing
- Oral neuromuscular training
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Umeå University
Traumatic Cervical Spine Instability
Anterior Only Surgery for Management of Traumatic Subaxial Cervical Spine Instability
Classic management of cervical spine sublaxation and dislocation is combined anterior and posterior approach. Unfortunately there are disadvantages for this approach like: increasing morbidity related to each approach, increasing…
- Trial name
- NCT03149497
- Testing
- anterior approach only in cervical spine trauma
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- arsany botros saleh
Spinal Fusion, Cervical Spine Degenerative Disease
Early Postoperative Home Exercise Program After Cervical Spine Surgery
The overall objective of this two-group randomized controlled trial is to gather preliminary evidence on the efficacy and safety of early postoperative exercise for improving disability, pain, and general physical health in…
- Trial name
- NCT02720172
- Testing
- Early Home Exercise Program, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Intubation, Intratracheal, Pain, Postoperative
Tracheal Tube Cuff Shape and Pressure
This is a randomized controlled trial focusing on the effect of different tracheal tube cuff shape; the tapered-shaped tracheal tube cuff versus the cylindrical-shaped tracheal cuff in anterior cervical spine surgery.
- Conditions
- Intubation, Intratracheal, Pain, Postoperative, Dysphonia
- Trial name
- NCT04591769
- Testing
- Different tracheal tube cuff design
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Cervical Radiculopathy, Cervical Myelopathy
The Collar Post Anterior Cervical Spine Surgery Study
The Anterior Cervical Discectomy and Fusion (ACDF) represents one of the most commonly performed spinal operations internationally, often in the context of symptomatic radiculopathy or myelopathy secondary to cervical…
- Trial name
- C-PASS (NCT03842072)
- Testing
- Cervical collar
- Where
- 2 sites in Canada
- Volunteers
- 244 people
- Sponsor
- Unity Health Toronto
Ankylosing Spondylitis (AS), Spine Fracture
A Retrospective Cohort Study About Surgical Efficacy for Lower Cervical Fractures in Ankylosing Spondylitis
The purpose of this retrospective cohort study was to observe and compare the efficacy of anterior cervical long segment fixation, posterior long segment fixation, and combined anterior and posterior fixation for the treatment of…
- Trial name
- NCT06873074
- Testing
- anterior long segment cervical fixation, posterior long segment cervical fixation, combined anterior and posterior fixation
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhou Fang
Dysphagia, Cervical Spine Disease
High Dose Steroids for Dysphagia
Few existing data currently indicates that anti-inflammatory drugs could help diminish the local cervical inflammation tough to cause the dysphagia, hoarseness and dyspnea after an anterior surgical approach to the spine.
- Trial name
- SHDD (NCT03256149)
- Testing
- Dexamethasone
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cervical Radiculopathy
Finnish Trial on Practices of Anterior Cervical Decompression (FACADE) Comparing Outpatient vs. Inpatient Care
FACADE is a prospective, randomized, controlled, parallel group non-inferiority trial comparing the traditional hospital surveillance (inpatient, patients staying in the hospital for 1-3 nights after surgery) to outpatient care…
- Trial name
- FACADE (NCT03979443)
- Testing
- Discharge on the day of surgery
- Where
- Finland
- Volunteers
- 104 people
- Sponsor
- Helsinki University Central Hospital