Clinical trials: Anterior Cruciate Ligament/Surgery
ACL Injury, ACL Tears
Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction
This is a prospective, multi-center, randomized, double-blind, placebo-controlled trial evaluating the efficacy of oral tranexamic acid (TXA) in improving postoperative outcomes following anterior cruciate ligament reconstruction…
- Conditions
- ACL Injury, ACL Tears, ACL Surgery
- Trial name
- NCT07115056
- Testing
- Tranexamic Acid (TXA)
- Where
- 6 sites in United States
- Sponsor
- Campbell Clinic
Anterior Cruciate Ligament Reconstruction
Anesthesic Techniques for Surgery of the Anterior Cruciate Ligament of the Knee in Ambulatory Surgery. Randomized Pilot Monocentric Trial
Surgery of the anterior cruciate ligament of the knee is frequently a young patient surgery. The post-operative pain of this surgery is managed according to recommendation.
- Trial name
- CLICA (NCT02257164)
- Testing
- Femoral nerve block, obturator nerve block, intraarticular injection
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anterior Cruciate Ligament Injury
Single- vs. Double-Bundle ACL Reconstruction
The purpose of this double-blind, randomized clinical trial to compare outcomes of single-bundle (SB) to anatomic double-bundle (DB) ACL reconstruction.
- Trial name
- NCT01319409
- Testing
- Anatomic Double-Bundle ACL Reconstruction, Anatomic Single-Bundle ACL Reconstruction
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Pittsburgh
ACL Injury, Anterior Cruciate Ligament Injuries
Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes
The purpose of this research is to find out whether the way information about surgery is presented to patients affects patient satisfaction, knowledge retention, and surgical outcomes such as anxiety
- Trial name
- NCT05273463
- Testing
- Video-Based Intervention, Classroom-Based Intervention
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Knee Injuries, Anterior Cruciate Ligament
Medical and Economical Evaluation of Computer-assisted Reconstruction of the Anterior Cruciate Ligament (ACL)
A poor outcome in anterior cruciate ligament (ACL) reconstruction is often related to tunnel position. The researchers believe that improving the accuracy of tunnel position will lead to an improved outcome in ACL surgery.
- Conditions
- Knee Injuries, Anterior Cruciate Ligament, Arthroscopy
- Trial name
- NCT00492609
- Where
- France
- Volunteers
- 285 people
- Sponsor
- University Hospital, Grenoble
Cruciate Ligament Reconstruction
Comparison of Tendon and Muscle-Tendon Semitendinosus Grafts After ACL Reconstruction
Aim: Comparison of tendon to bone ingrowth in bone tunnels and intra-articular remodeling of the graft after anterior cruciate ligament surgery with a muscle-tendon graft and those with a tendon graft.
- Trial name
- CandyStripe (NCT07404046)
- Testing
- ACL reconstruction
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Dubrava
Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries
Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries
This observational study aims to evaluate the long-term recovery and clinical outcomes of patients undergoing minimally invasive (arthroscopic) surgeries for sports-related shoulder and knee injuries.
- Conditions
- Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries, Tibial Meniscus Injuries, Shoulder Dislocation or Subluxation
- Trial name
- SK-COHORT (NCT07501013)
- Testing
- Standard of Care Shoulder Arthroscopy, Standard of Care Knee Arthroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Surgical Adhesions
JOCOAT Safety and Tolerability Clinical Trial GLAD-04
This study will assess the safety and efficacy of a new liquid anti-adhesion device, JOCOAT(TM) APN-3003 in patients undergoing knee anterior cruciate ligament reconstruction (ACLR) surgery.
- Trial name
- NCT07081815
- Testing
- JOCOAT(TM) APN-3003
- Volunteers
- 24 people
- Sponsor
- ARC Medical Inc.
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament (ACL) Revision Surgery: French National Study
This is a national multicentric study led by the French Arthroscopy Society (SFA) evaluating clinical practice in anterior cruciate ligament (ACL) revision surgery (epidemiological data, morphological data, operative data…
- Trial name
- NCT06379308
- Testing
- questionaries, datas of medical record
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ACL Surgery, ACL Injuries
Developing and Validating the Risk-taking Intention and Sport Engagement After ACL Reconstruction (RISE-ACL) Scale
Psychological factors play a critical role in recovery following anterior cruciate ligament (ACL) reconstruction. While tools such as the ACL - Return to Sport after Injury (ACL-RSI) focus on psychological readiness, emphasizing…
- Conditions
- ACL Surgery, ACL Injuries, ACL Reconstruction
- Trial name
- RISE-ACL (NCT06748066)
- Testing
- RISE-ACL development, RISE-ACL scale validation
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Caen
Knee Arthritis Osteoarthritis, Cruciate Ligament Rupture
A Retrospective and Prospective Study: Monocompartimental Knee Arthroplasty Combined With Anterior Cruciate Ligament Reconstruction Surgery - a Pilot Study
This study aims to collect datas about patient who underwent simultaneous monocompartimental knee replacement and anterior cruciate ligament recontruction
- Trial name
- MONO-LCA (NCT07377669)
- Testing
- UKA + ACLr
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Ruptured Anterior Cruciate Ligament, Partial Tear Ligament
Proprioceptive Function, Postural Stability & Clinical Outcome After Stump Preserving Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) is known to serve a number of functions in the knee joint. Besides providing mechanical stability, it also contributes to proprioceptive function.
- Trial name
- NCT01348945
- Testing
- conventional ACL rehabilitation program
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament
Effects of Femoral vs Saphenous Nerve Blocks on Function After ACL Repair
The primary objective of the study is to compare motor strength in knee extension between two groups of patients. One group receiving a proximal thigh block of the femoral nerve, and one receiving a distal thigh block of the…
- Trial name
- NCT01919658
- Testing
- nerve block
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Robert A. Gallo
Anterior Cruciate Ligament Reconstruction, Subchondral Microfractures of Tibia
Subchondral Microfracture of Tibia After Arthroscopic Anterior Cruciate Ligament Surgery Reconstruction
The arthroscopic anterior cruciate (ACL) ligament reconstruction surgery is widespread. The creation of the tibial tunnel, retrograde or antegrade, is not consensual.
- Trial name
- NCT01588977
- Where
- 3 sites in France
- Volunteers
- 43 people
- Sponsor
- Hospital Ambroise Paré Paris
ACL - Anterior Cruciate Ligament Rupture
Microbiological Molecular Profile of the Knee Joint During Primary Reconstruction or Revision Surgery of the ACL
Anterior cruciate ligament (ACL) reconstructions are common surgical procedures, but a significant number fail for reasons that are not fully understood.
- Trial name
- INFECTIOGEN (NCT07009392)
- Testing
- NGS Analysis
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Injuries
Operation Korsband
This study aims to investigate if a detailed and comprehensive survey can identify, explain and prevent the risk factors for ACL injury.
- Trial name
- NCT05752695
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Linnaeus University
Anterior Cruciate Ligament Injuries, Posterior Cruciate Ligament Tear
Interference Screw Mectascrew-C Postmarket Study
An observational prospective study with the aim to analyze the presence at 6 months of a specific composite IS (Medacta Mectascrew C) in the reconstructive treatment of ruptured ACL or PCL by means of an autograft or allograft.
- Trial name
- NCT05791656
- Testing
- Mectascrew-C
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Medacta International SA
Anterior Cruciate Ligament Reconstruction
Prevention of Skeletal Muscle Adaptations to Traumatic Knee Injury and Surgery
Traumatic knee injury is common and highly debilitating. Surgical reconstruction/repair improves knee biomechanics and function, but neuromuscular dysfunction persist for years despite rehabilitation, hindering resumption of…
- Trial name
- NCT02945553
- Testing
- Neuromuscular electrical stimulation, Microstimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Vermont
Anterior Cruciate Ligament Tear
Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing
The purpose of this study is to determine which surgical method is better for anterior cruciate ligament teas in outcomes.
- Trial name
- NCT01580722
- Testing
- early reconstruction, delay reconstruction
- Where
- Iran
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Postoperative Pain, Acute, Anterior Cruciate Ligament Injuries
Effectiveness Comparison Between Continuous Cryotherapy and Ice Pack Therapy After Anterior Cruciate Ligament Reconstruction Surgery
A randomized controlled trial study conducted by comparing the VAS score, swelling condition, knee ROM and patient's satisfactory score between applying ice pack cold therapy and applying continuous compressive cryotherapy in a…
- Conditions
- Postoperative Pain, Acute, Anterior Cruciate Ligament Injuries, Cryotherapy Effect
- Trial name
- NCT06629285
- Testing
- Continuous compression cryotherapy, Conventional ice treatment
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)