Clinical trials: Anterior Cruciate Ligament
Anterior Cruciate Ligament Injury
Effect of Dual Tasks on Gait Symmetry After Anterior Cruciate Ligament Reconstruction
Individuals who received anterior cruciate ligament (ACL) reconstruction demonstrated lower extremity movement asymmetries. The purpose of this study was to determine if psychological impairment was a contributor to lower…
- Trial name
- NCT04461145
- Testing
- command
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
Application of MI-BCI Combined With tDCS in Early Rehabilitation After Anterior Cruciate Ligament Reconstruction
To recover lower-limb motor function is a primary goal for rehabilitation after anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT06513988
- Testing
- MI-BCI combined with tDCS treatment
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Air Force Military Medical University, China
Anterior Cruciate Ligament Reconstruction
Prevention of Skeletal Muscle Adaptations to Traumatic Knee Injury and Surgery
Traumatic knee injury is common and highly debilitating. Surgical reconstruction/repair improves knee biomechanics and function, but neuromuscular dysfunction persist for years despite rehabilitation, hindering resumption of…
- Trial name
- NCT02945553
- Testing
- Neuromuscular electrical stimulation, Microstimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Vermont
Anterior Cruciate Ligament Tear
Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing
The purpose of this study is to determine which surgical method is better for anterior cruciate ligament teas in outcomes.
- Trial name
- NCT01580722
- Testing
- early reconstruction, delay reconstruction
- Where
- Iran
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss
Blood Flow Restriction Training in Rehabilitation Patients
Occlusion training, resistance exercise performed with a specialized venous tourniquet, leads to beneficial changes in muscle at low resistance and minimal stress on the nearby joint.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
- Trial name
- NCT02174770
- Testing
- Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Brooke Army Medical Center
Patellar Tendinopathy, Anterior Cruciate Ligament Reconstruction
Quantifying Patellar Tendon Microstructure Using DTI
The goal of this observational study is to understand how diffusion tensor imaging (DTI) relates to other traditional measures and knee function.
- Trial name
- NCT06381492
- Testing
- MRI, Ultrasound (US), Neuromuscular electric stimulation (NMES)
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Anterior Cruciate Ligament Injuries
Evaluation of the Results of Two Different Methods in Management of Antero-lateral Instability of the Knee
This randomized clinical study will be conducted to compare the results of anterior cruciate ligament reconstruction (ACLR) combined with either anterolateral ligament reconstruction using peroneus longus autograft or…
- Trial name
- NCT06222814
- Testing
- ACL reconstruction combined with anterolateral ligament reconstruction using peroneus longus autograft, ACL reconstruction combined with extra-articular tenodesis (Modified Lemaire)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
ACL Injury
Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study
It is estimated that 48 out of 10,000 people, in the United States, will tear their anterior cruciate ligament (ACL) annually and undergo ACL reconstruction (ACLR).
- Trial name
- NCT04958733
- Testing
- Autologous bone grafting, Absence of autologous bone grafting
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Hartford Hospital
Rotator Cuff Repair, Anterior Cruciate Ligament Reconstruction
Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study
Postoperative pain is usually treated with opioids that have undesirable and sometimes dangerous side effects (e.g., vomiting and respiratory depression)-and yet over 80% of patients still experience inadequate pain relief.
- Conditions
- Rotator Cuff Repair, Anterior Cruciate Ligament Reconstruction, Ankle Arthrodesis or Arthroplasty, Hallux Valgus Correction
- Trial name
- NCT03481725
- Testing
- ACTIVE peripheral nerve stimulation with a percutaneously inserted lead and wearable stimulator (SPR Therapeutics, Cleveland, Ohio)
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Diego
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction
ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws
The goal of this clinical trial is to compare the outcome of 2 different screws for Anterior cruciate ligament reconstruction. The main question is if the human allogeneic cortical bone screw reduces tunnel widening in comparison…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injury
- Trial name
- NCT06357091
- Testing
- ACL reconstruction with Shark Screw ACL®, ACL reconstruction with biocomposite screw (Mecta)
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Alexander Rofner-Moretti
Postoperative Pain, Acute, Anterior Cruciate Ligament Injuries
Effectiveness Comparison Between Continuous Cryotherapy and Ice Pack Therapy After Anterior Cruciate Ligament Reconstruction Surgery
A randomized controlled trial study conducted by comparing the VAS score, swelling condition, knee ROM and patient's satisfactory score between applying ice pack cold therapy and applying continuous compressive cryotherapy in a…
- Conditions
- Postoperative Pain, Acute, Anterior Cruciate Ligament Injuries, Cryotherapy Effect
- Trial name
- NCT06629285
- Testing
- Continuous compression cryotherapy, Conventional ice treatment
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Anterior Cruciate Ligament Reconstruction (ACLR)
The Effect of Lateral Extra-Articular Tenodesis on Lower-Extremity Lean Mass Recovery Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to determine whether the addition of Lateral Extra-Articular Tenodesis (LET) influences postoperative lower-extremity LM recovery following bone-patellar tendon-bone (BTB) Anterior Cruciate Ligament…
- Trial name
- NCT07777458
- Testing
- Bone-patellar Tendon-bone (BTB), Bone-patellar Tendon-bone (BTB) and Lateral Extra-Articular Tenodesis (LET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Sports Injury
Clinical Study of Platelet-rich Plasma Promoting Tendon-bone Healing in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injury is a common knee injury, which seriously affects the living ability and sport level of the injured. ACL reconstruction is the main method to treat ACL injury.
- Trial name
- NCT04659447
- Testing
- Platelet-Rich Plasma
- Volunteers
- 60 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Anesthesia; Reaction
Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically
This study aims to compare continuous femoral nerve block with adductor canal block after anterior cruciate ligament reconstruction arthroscopically，especially in the effect on quadriceps strength; and to evaluate which regional…
- Trial name
- NCT02355093
- Testing
- adductor canal block (ACB), Femoral nerve block (FNB), ropivacaine
- Volunteers
- 40 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Anterior Cruciate Ligament Reconstruction
Whole Body Vibration in Individuals Submitted to ACL
The purpose of this study is to analyze the immediate effects of two exercises protocols on the whole body vibration, on the strength of the thigh muscles, joint position sense of the knee and balance in individuals submitted to…
- Trial name
- NCT02609971
- Testing
- Vibration at 50 Hz
- Volunteers
- 46 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Post Operative Swelling
Geko™ Device in Prevention of Pain and Swelling Following Knee Arthroscopy
report on post-operative effectiveness of the Geko™ device in prevention of pain and swelling after arthroscopic anterior cruciate ligament reconstruction and repairs
- Trial name
- NCT07896499
- Testing
- Geko, control
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Achilles Allograft With or Without InternalBrace for ACL Revision Surgery
This study evaluated outcomes after revision anterior cruciate ligament reconstruction using Achilles tendon allografts with a calcaneal bone block, with or without additional InternalBrace augmentation.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Graft Failure, Knee Instability
- Trial name
- ACL-AlloRev (NCT07564336)
- Testing
- Revision ACL Reconstruction With Achilles Tendon Allograft and InternalBrace Augmentation, Revision ACL Reconstruction With Achilles Tendon Allograft Without InternalBrace Augmentation
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Graz
ACL Reconstruction
A Multi-centre, Double-blind RCT to Investigate the Effect of Alendronate on Knee Function Following ACLR
Anterior cruciate ligament (ACL) is the key ligament connecting the femur to tibia that helps stabilising the knee joint. ACL tear is common.
- Trial name
- NCT05527548
- Testing
- Alendronate (ALN)
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen