Clinical trials: Anterior Cruciate Ligament Reconstruction
Patellar Tendinopathy, Anterior Cruciate Ligament Reconstruction
Quantifying Patellar Tendon Microstructure Using DTI
The goal of this observational study is to understand how diffusion tensor imaging (DTI) relates to other traditional measures and knee function.
- Trial name
- NCT06381492
- Testing
- MRI, Ultrasound (US), Neuromuscular electric stimulation (NMES)
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
ACL Injury
Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study
It is estimated that 48 out of 10,000 people, in the United States, will tear their anterior cruciate ligament (ACL) annually and undergo ACL reconstruction (ACLR).
- Trial name
- NCT04958733
- Testing
- Autologous bone grafting, Absence of autologous bone grafting
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Hartford Hospital
Rotator Cuff Repair, Anterior Cruciate Ligament Reconstruction
Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study
Postoperative pain is usually treated with opioids that have undesirable and sometimes dangerous side effects (e.g., vomiting and respiratory depression)-and yet over 80% of patients still experience inadequate pain relief.
- Conditions
- Rotator Cuff Repair, Anterior Cruciate Ligament Reconstruction, Ankle Arthrodesis or Arthroplasty, Hallux Valgus Correction
- Trial name
- NCT03481725
- Testing
- ACTIVE peripheral nerve stimulation with a percutaneously inserted lead and wearable stimulator (SPR Therapeutics, Cleveland, Ohio)
- Where
- 6 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Diego
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction
ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws
The goal of this clinical trial is to compare the outcome of 2 different screws for Anterior cruciate ligament reconstruction. The main question is if the human allogeneic cortical bone screw reduces tunnel widening in comparison…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injury
- Trial name
- NCT06357091
- Testing
- ACL reconstruction with Shark Screw ACL®, ACL reconstruction with biocomposite screw (Mecta)
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Alexander Rofner-Moretti
Postoperative Pain, Acute, Anterior Cruciate Ligament Injuries
Effectiveness Comparison Between Continuous Cryotherapy and Ice Pack Therapy After Anterior Cruciate Ligament Reconstruction Surgery
A randomized controlled trial study conducted by comparing the VAS score, swelling condition, knee ROM and patient's satisfactory score between applying ice pack cold therapy and applying continuous compressive cryotherapy in a…
- Conditions
- Postoperative Pain, Acute, Anterior Cruciate Ligament Injuries, Cryotherapy Effect
- Trial name
- NCT06629285
- Testing
- Continuous compression cryotherapy, Conventional ice treatment
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Anterior Cruciate Ligament Reconstruction (ACLR)
The Effect of Lateral Extra-Articular Tenodesis on Lower-Extremity Lean Mass Recovery Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to determine whether the addition of Lateral Extra-Articular Tenodesis (LET) influences postoperative lower-extremity LM recovery following bone-patellar tendon-bone (BTB) Anterior Cruciate Ligament…
- Trial name
- NCT07777458
- Testing
- Bone-patellar Tendon-bone (BTB), Bone-patellar Tendon-bone (BTB) and Lateral Extra-Articular Tenodesis (LET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Sports Injury
Clinical Study of Platelet-rich Plasma Promoting Tendon-bone Healing in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injury is a common knee injury, which seriously affects the living ability and sport level of the injured. ACL reconstruction is the main method to treat ACL injury.
- Trial name
- NCT04659447
- Testing
- Platelet-Rich Plasma
- Volunteers
- 60 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Anesthesia; Reaction
Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically
This study aims to compare continuous femoral nerve block with adductor canal block after anterior cruciate ligament reconstruction arthroscopically，especially in the effect on quadriceps strength; and to evaluate which regional…
- Trial name
- NCT02355093
- Testing
- adductor canal block (ACB), Femoral nerve block (FNB), ropivacaine
- Volunteers
- 40 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Anterior Cruciate Ligament Reconstruction
Whole Body Vibration in Individuals Submitted to ACL
The purpose of this study is to analyze the immediate effects of two exercises protocols on the whole body vibration, on the strength of the thigh muscles, joint position sense of the knee and balance in individuals submitted to…
- Trial name
- NCT02609971
- Testing
- Vibration at 50 Hz
- Volunteers
- 46 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Achilles Allograft With or Without InternalBrace for ACL Revision Surgery
This study evaluated outcomes after revision anterior cruciate ligament reconstruction using Achilles tendon allografts with a calcaneal bone block, with or without additional InternalBrace augmentation.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Graft Failure, Knee Instability
- Trial name
- ACL-AlloRev (NCT07564336)
- Testing
- Revision ACL Reconstruction With Achilles Tendon Allograft and InternalBrace Augmentation, Revision ACL Reconstruction With Achilles Tendon Allograft Without InternalBrace Augmentation
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Graz
ACL Reconstruction
A Multi-centre, Double-blind RCT to Investigate the Effect of Alendronate on Knee Function Following ACLR
Anterior cruciate ligament (ACL) is the key ligament connecting the femur to tibia that helps stabilising the knee joint. ACL tear is common.
- Trial name
- NCT05527548
- Testing
- Alendronate (ALN)
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Reconstruction
Effect of PRP Versus BMC in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is an important stabilizer of knee during daily activity and exercise. The ruptured ACL need to be reconstructed by a new tendon graft which passed the bone tunnel and joint during operation.
- Trial name
- NCT05191732
- Testing
- Platelet-Rich Plasma; Bone marrow concentrate
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital