Clinical trials: Anterior Disc Displacement
Intervertebral Disk Degeneration, Intervertebral Disk Displacement
Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™
Anterior cervical discectomy and fusion (ACDF) has shown good treatment results for a variety of cervical spine diseases such as herniated intervertebral disc (HIVD), cervical spondylotic radiculopathy (CSR) and cervical…
- Conditions
- Intervertebral Disk Degeneration, Intervertebral Disk Displacement, Ossification of Posterior Longitudinal Ligament
- Trial name
- NCT01615328
- Testing
- Cervios ChronOs, Bonion
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Seoul National University Hospital
Temporomandibular Joint Disorders
Effect of Laser Therapy Versus Anterior Re-positioning Splint in the Treatment of Disc Displacement With Reduction
comparing the effects of Laser therapy with anterior re-positioning splint and a placebo group on clinical signs and symptoms of temporo-mandibular dis-function and assessing articular disc morphology and configuration with…
- Trial name
- NCT03576079
- Testing
- Laser therapy, anterior re-positioning splint, inactive Laser therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Herniated Disc, Radiculopathy
Slotted Hole Versus Fixed Hole C-Tek
The purpose of this study is to compare the fusion rates between the EBI, LLC C-Tek™ Anterior Cervical Plate, Slotted Hole Design versus the Fixed Hole Design.
- Conditions
- Herniated Disc, Radiculopathy, Spondylolysis
- Trial name
- NCT00585923
- Testing
- Fixed hole C-Tek™ Plate, Slotted hole C-Tek™ Plate
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Zimmer Biomet
Anterior Disc Displacement
Ultrasound-Guided Botulinum Toxin A Injection for TMJ Disc Displacement With Reduction
This clinical trial was designed to evaluate the effectiveness of ultrasonography-guided botulinum toxin type A (BTX-A) injection into the lateral pterygoid muscle for the management of temporomandibular joint (TMJ) anterior disc…
- Trial name
- NCT07076355
- Testing
- Botulinum Toxin type a (Botox)
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Herniated Disk, Temporomandibular Disorders
Randomized Clinical Trial of Treatment for Temporomandibular Joint (TMJ) Disc Displacement
The effectiveness of physical therapy for treatment of anterior disc displacement without reduction of temporomandibular disorders has not been well defined.
- Trial name
- NCT00936338
- Testing
- splint and joint mobilization self exercise
- Where
- Japan
- Volunteers
- 44 people
- Sponsor
- Tokyo Medical and Dental University
Anterior Disc Displacement
Treatment Outcome of Supervised Exercise and Home Exercise in Patients with Symptomatic Disc Displacement with Reduction
The aim of the study is to evaluate the treatment outcome of supervised exercise and home exercise in patients with symptomatic disc displacement with reduction.
- Trial name
- NCT06651814
- Testing
- Supervised Exercise Group, Home Exercise Group
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
TMJ Disc Disorder
Therapeutic Effect of Microfragmented Adipose Tissue (Lipogems) Injection on Maximum Interincisal Opening Versus Injectable Platelet-rich Plasma (PRP) for the Treatment of Anterior Disc Displacement With Reduction : A Randomized Clinical Trial
this procedure is to remove inflammatory mediators, reduce friction, stimulate the production of new synovial fluid, eliminate suction-cup effect.
- Trial name
- NCT07107399
- Testing
- microfragmented adipose tissue, platelet-rich plasma
- Volunteers
- 16 people
- Sponsor
- Cairo University
Lumbar Disc Herniation, Radiculopathy Lumbar
Comparison of the Effectiveness of Erector Spina Plane Block and Transforaminal Anterior Epidural Injections
Low back pain is one of the leading causes of disability and its social burden and economic cost are quite high. The lifetime prevalence in the population is frequently reported between 40% and 70%.
- Trial name
- NCT05719792
- Testing
- Transforaminal Epidural Steroid Injection, Erector Spina Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Disorder (TMD), Internal Derangement
Computer Guided Single Needle Arthrocentesis
The intra-articular injection is considered the first line of minimally invasive treatment in temporomandibular joint with internal derangement (TMJ-ID) patients who do not respond to conservative treatment.
- Conditions
- Temporomandibular Disorder (TMD), Internal Derangement, Anterior Disc Displacement
- Trial name
- NCT07306936
- Testing
- Computer-guided single needle arthrocentesis, conventional free hand single needle arthrocentesis
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Cervical Spondylosis, Degenerative Intervertebral Discs
An ACDF Multi-Center Study Using ViviGen Cellular Bone Matrix
The purpose of this post-market study is to collect data on ViviGen and how its use affects fusion rates in the cervical spine when used as additional grafting material to fill the cervical spacer.
- Conditions
- Cervical Spondylosis, Degenerative Intervertebral Discs, Herniated Disc
- Trial name
- NCT02814825
- Testing
- ViviGen
- Volunteers
- 100 people
- Sponsor
- DePuy Spine
TMJ Disc Disorder
Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials
comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.
- Trial name
- NCT06441279
- Testing
- intra-articular injection with Platelet lysate (PL)., intra-articular injection with Hyaluronic Acid.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Internal Derangement
Intra-articular Injection of Medications in TMJ After Arthrocentsis
The aim of this study: to evaluate the injection of hyaluronic acid and corticosteroids mixture leads to better clinical outcomes in terms of improve maximum mouth opening and reduce pain compared with hyaluronic acid and prp…
- Trial name
- NCT07598253
- Testing
- Arthrocentesis with ringer solution
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Temporomandibular Joint Internal Derangement (ADWR)
Evaluation of Intravenous Sodium Valproate on Interleukin-6 Levels in Patients With TMJ Disc Displacement
This study aims to evaluate if adding the medication Sodium Valproate to a standard jaw procedure (arthrocentesis) can help reduce inflammation and improve healing in patients with certain jaw joint problems.
- Trial name
- NCT07487675
- Testing
- sodium valproate, TMJ Arthrocentesis
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Temporomandibular Disorders (TMDs), Myofascial Pain - Dysfunction Syndrome of TMJ
Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in the Management of Temporomandibular Joint Disorders
Occlusal splint therapy is a well-established conservative approach for the management of temporomandibular disorders (TMDs); however, variability in clinical outcomes suggests that no single splint design is universally optimal.
- Conditions
- Temporomandibular Disorders (TMDs), Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint, Anterior Disc Displacement
- Trial name
- NCT07760428
- Testing
- Conventional Stabilization Splints, 3d printed Stabilization splint, Novel hybrid stabilization splint
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Temporomandibular Joint Disorders
Evaluation of the Effect of Dextrose Prolotherapy Versus Dry Needling Therapy
The hypertonic dextrose injection; Prolotherapy is a proliferation injection therapy that aims to trigger a low-grade inflammatory response inside the (TMJ), with the resultant captivation of abundant fibroblasts that regenerate…
- Trial name
- NCT05821985
- Testing
- The study group, The Control group
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
TMJ Disc Disorder
Therapeutic Effect of Proliferative Therapy (Prolotherapy) on Pain Using Injectable Hypertonic Dextrose 25% Versus Injectable Dextrose 10% in Retrodiscal Tissues in Patients With Anterior Disc Displacement With Reduction: A Randomized Clinical Trial .
prolotherapy is an injection-based treatment method used to alleviate pain, particularly musculoskeletal pain associated with chronic ligament and tendon injuries.
- Trial name
- NCT06859034
- Testing
- injection of dextrose 10% in retrodiscal tissues, injection of dextrose 25% in retrodiscal tissues
- Volunteers
- 24 people
- Sponsor
- Cairo University
Temporomandibular Joint Dysfunction Syndrome, Arthrocenteses
Arthrocentesis Alone Versus Arthrocentesis With Hyaluronic Acid Injection
Comparison between Arthrocentesis alone arthrocentesis with hyaluronic acid injection in management of temporomandibular joint dysfunction in the form of anterior disc displacement with reduction.
- Conditions
- Temporomandibular Joint Dysfunction Syndrome, Arthrocenteses, Hyaluronic Acid
- Trial name
- NCT05962619
- Testing
- arthrocentesis alone, arthrocentesis with hyaluronic acid injection
- Volunteers
- 42 people
- Sponsor
- Assiut University