Clinical trials: Anterior Vaginal Wall Prolapse
Anterior Vaginal Wall Prolapse, Pelvic Organ Prolapse
Transobturator Lateral Suspension in Anterior Colporrhaphy
Anterior colporrhaphy (AC) is commonly used for anterior vaginal wall prolapse, but suffers high recurrence rates. This randomized trial assessed whether adding transobturator lateral suspension (TOLS) to AC decreases objective…
- Trial name
- TLSAC (NCT07144397)
- Testing
- TOLS
- Where
- Slovenia
- Volunteers
- 44 people
- Sponsor
- University Medical Centre Maribor
Vaginal Prolapse
The Use of Avaulta for Anterior Repair
Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age.
- Trial name
- NCT00918099
- Testing
- Avaulta mesh, Anterior repair
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Zealand University Hospital
Pelvic Organ Prolapse
Anterior Prolapse Repair With and Without Graft Augmentation
This is a randomized control trial comparing anterior colporrhaphy with augmentation with dermal allograft (ARCUS) to anterior colporrhaphy with a suture-based repair (native tissue).
- Trial name
- ARCUS (NCT04085952)
- Testing
- dermal graft (ARCUS repliform) for anterior colporrhaphy, suture based anterior colporrhaphy
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Cystocele, Uterine Prolapse
Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair
The purpose of this study is determine whether grafted anterior vaginal prolapse repair is more effective and associated with less complications than prolapse repair with suture.
- Conditions
- Cystocele, Uterine Prolapse, Urinary Incontinence
- Trial name
- NCT00535301
- Testing
- grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cystocele, Cystocele, Midline
Continuous Stitches Versus Simple Interrupted Stitches for Anterior Colporrhaphy
The anterior vaginal wall is the segment most commonly affected by prolapse. Traditionally, anterior vaginal wall prolapse is repaired via anterior colporrhaphy (native tissue repair), which is known to have a high recurrence…
- Conditions
- Cystocele, Cystocele, Midline, Vaginal Prolapse, Prolaps Bladder
- Trial name
- NCT05449054
- Testing
- Anterior colporrhaphy
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Pelvic Organ Prolapse
Anterior Vaginal Wall Repair With Mesh in Combination With TVT-O to Reduce Urinary Stress Incontinence
Urinary stress incontinence is defined as leakage of urine during stress. Urinary stress incontinence is a health problem with social, economic and psychological consequences.
- Trial name
- NCT01507714
- Testing
- Preventive transobturator tension free vaginal tape
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- HaEmek Medical Center, Israel
Anterior Vaginal Wall Prolapse
Mesh Repair of Anterior Vaginal Wall Prolapse
The purpose of this study is to determine whether reenforcement with polypropylen mesh compared with traditional anterior colporrhaphy for anterior vaginal wall prolapse results in fewer recurrences.
- Trial name
- NCT00420225
- Testing
- Low-weight prolypropylene mesh
- Where
- Finland
- Volunteers
- 202 people
- Sponsor
- Tampere University
Anterior Vaginal Wall Prolapse, Cystocele
Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
The purpose of this study is to evaluate the success rate of cystocele repair using polypropylene mesh or porcine dermis compared to that of anterior colporrhaphy in a prospective randomized fashion.
- Conditions
- Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
- Trial name
- OARS (NCT01393171)
- Testing
- Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Catheter Related Complication, Anterior Vaginal Wall Prolapse
Comparison of 1 Versus 2 Days Post-Operative Catheterization After Anterior Colporrhaphy
Patients who undergo anterior vaginal wall plastic surgery and place the bladder catheter during surgery are selected. The purpose of the study is to evaluate the presence of statistically significant differences in bladder…
- Trial name
- NCT06429228
- Testing
- Catheter removal after surgery
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Pelvic Organ Prolapse, Cystocele
Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS
Surgical correction of the prolapse in the anterior compartment remains one of the major challenges in urogynecology. Paravaginal defect in level II of vaginal fixation results in the majority of cystoceles.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Cystocele and Incomplete Uterovaginal Prolapse
- Trial name
- STARS (NCT05602246)
- Testing
- Transobturator cystocele repair, Anterior colporrhaphy
- Where
- 8 sites in Czechia, Slovakia
- Volunteers
- 592 people
- Sponsor
- Charles University, Czech Republic
Anterior Vaginal Wall Prolapse, Vaginal Apex/Uterine Prolapse
Demonstrate the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
A prospective, single arm, pre-market, multi-center clinical study to evaluate the safety and performance of the SRS (Lyra Medical) vaginal mesh in POP patients
- Trial name
- NCT02209337
- Testing
- SRS
- Where
- 3 sites in Hungary, Israel
- Volunteers
- 20 people
- Sponsor
- Lyra Medical Ltd.
Cystocele, Rectocele
Clinical Performance of the GYNECARE PROLIFT + M* Pelvic Floor Repair System as a Device for Pelvic Organ Prolapse
The purpose of this study is to evaluate the clinical performance of the PROLIFT system with a new lighter-weight mesh in repair of vaginal prolapse.
- Conditions
- Cystocele, Rectocele, Enterocele
- Trial name
- NCT00833001
- Testing
- GYNECARE PROLIFT+M* Pelvic Floor Repair System
- Where
- 8 sites in Belgium, France and 2 more
- Volunteers
- 126 people
- Sponsor
- Ethicon, Inc.