Clinical trials: Anthocyanins
Anthocyanin Metabolism
Gastric pH and Anthocyanin Absorption
Anthocyanins are phytonutrients that provide blue, purple and red colors to fruits and vegetables. The purpose of the study is to determine whether absorption of anthocyanins occurs in the acid pH of the stomach and to determine…
- Trial name
- NCT01122160
- Testing
- omeprazole
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Resistance Exercise Performance, Cognitive Function
Effects of New Zealand Blackcurrant Supplementation on Exercise and Cognitive Performance in Resistance-Trained Adults
New Zealand blackcurrant (NZBC) is a supplement made from a berry naturally rich in plant compounds called anthocyanins. Researchers have studied these compounds for years and found that they may help the body by improving blood…
- Conditions
- Resistance Exercise Performance, Cognitive Function, Anaerobic Performance, Dietary Supplementation Athletic Performance
- Trial name
- NZBC-FORCE (NCT07619976)
- Testing
- Low-dose Blackcurrant Supplement, High-dose Blackcurrant Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jacksonville State University
Depressive Symptoms
Berries, Bugs, and the Blues
This study aims to investigate the impact of daily freeze-dried blueberry powder consumption on the gut microbiota, fecal short chain fatty acids, and depressive symptom severity in 40older, sedentary adults with depressive…
- Trial name
- NCT05817383
- Testing
- Freeze-dried Blueberry Powder
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hebrew SeniorLife
Diabetes, Insulin Resistance
Glycemic Index and Polyphenol Bioavailability of Potatoes
The purpose of this study is to determine the glycemic index of four varieties of potatoes and to determine the bioavailability of polyphenols contained in these potatoes.
- Trial name
- GI (NCT01053793)
- Testing
- Glycemic response to different varieties of potatoes
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Guelph Food Research Centre
Glucose Intolerance, Glucose Metabolism Disorders
Acute Study of Anthocyanin-rich Bilberry and Polyphenol-rich Apple Extracts on Postprandial Glycaemic Response
Strategies to control chronic postprandial hyperglycaemia by optimizing the functionality of foods would strengthen efforts to reduce the risk of developing T2D in the general population.
- Trial name
- NCT04004182
- Testing
- Fruit bar with addition of polyphenols
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Cardiovascular Disease
Investigation of the Atherogenic Effects of Uric Acid-modified in Endothelial Dysfunction and the the Preventional Mechanism by Anthocyanidines
The purpose of this study is to confirm the protective effect and mechanism of anthocyanins on hyperuricemia patients with Cardiovascular disease.
- Trial name
- NCT02797028
- Testing
- Anthocyanidins capsule, Allopurinol
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Bioavailability, Cardiovascular Disease
Bioavailability and Metabolism of Anthocyanins Following Acute Cranberry Consumption
This study hypothesis is that anthocyanins from cranberry juice are bioavailable and can be measured in blood and urine after a single acute consumption of cranberry juice.
- Trial name
- NCT00809900
- Testing
- Experimental
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Tufts University
Endothelial Dysfunction, Aging
Effects of Aronia Berries on Vascular Endothelial Function and the Gut Microbiota in Middle-Aged/Older Adults
Aging is the primary risk factor for cardiovascular disease (CVD) largely due to vascular endothelial dysfunction, a major initial step in the development of atherosclerosis.
- Trial name
- NCT03824041
- Testing
- Aronia full spectrum - half dose, Aronia full spectrum - full dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Cardiovascular Physiology
Effects of Tart Cherry and Aronia Extract Supplementation on Selected Physiological Parameters in Endurance-Trained Men
This study will evaluate the effects of four weeks of oral supplementation with a double-standardized tart cherry (Prunus cerasus) and aronia (Aronia melanocarpa) extract on cardiovascular regulation and exercise performance in…
- Trial name
- NCT07885098
- Testing
- Standardized Tart Cherry and Aronia Extract
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Mood, Affect
Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults
This study aims to investigate whether consuming a drink containing powdered blueberries (equivalent to 150 g of fresh fruit) can improve mood and executive function in healthy emerging adults.
- Conditions
- Mood, Affect, Executive Function
- Trial name
- NCT05717452
- Testing
- Blueberry drink
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hypertension, Hypercholesterolemia
Effects of Purple Vegetables on Cardiovascular Disease (CVD) Risk Factors
The hypothesis is that richly coloured purple vegetables, rich in polyphenolic compounds including anthocyanins will have higher antioxidant and other biological activities, than more lightly coloured versions of these foods.
- Conditions
- Hypertension, Hypercholesterolemia, Type II Diabetes, Obesity
- Trial name
- NCT01564498
- Testing
- vegetable
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Guelph
Inflammation;Muscle(S), Oxidative Stress Injury
Effect of 8-week Supplementation With Black Chokeberry on Recovery in Highly Trained Rowers
Purpose: To analyze the effects of 8-week supplementation with anthocyanin compounds contained in black chokeberry (Aronia melanocarpa) on indicators of inflammation and oxidative stress.
- Conditions
- Inflammation;Muscle(S), Oxidative Stress Injury, Permeability; Increased
- Trial name
- NCT06133751
- Testing
- black chokeberry (Aronia melanocarpa)
- Where
- Poland
- Volunteers
- 15 people
- Sponsor
- Poznan University of Physical Education
Healthy, Dietary Bioavailability
Effect of Fruit Elicitation With Melatonin on Human Health
The goal of this clinical trial is to learn if treating fruits with melatonin helps the body absorb and use healthy plant compounds. It will also learn how much melatonin from the fruits is taken up by the body.
- Conditions
- Healthy, Dietary Bioavailability, Plant Extracts, Phenolic Compounds
- Trial name
- NCT07192835
- Testing
- Juice from untreated control fruits, Juice from melatonin-treated fruits
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Healthy Aging
Food Anthocyanins and Flavanols as a Strategy for a Healthy Ageing: Cardiovascular Health and Cognitive Performance
The study examines the effect of cocoa flavanols, red-berries anthocyanins or a combination of both on markers of cardiovascular health and cognition.
- Trial name
- POLYAGE (NCT04348162)
- Testing
- Cocoa flavanols and berries anthocyanins
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Healthy
Anthocyanin Dose-escalation Study in Healthy Young Adults
Anthocyanins are naturally existing, polyphenolic compounds found in the vacuolar sap of the epidermal tissues of flowers and fruits, with a pink, red, blue, or purple color.
- Trial name
- NCT02760511
- Testing
- Anthocyanin
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Shaoguan University
Diabetes Mellitus，Type 2
Purified Anthocyanins Supplementation and High-Density Lipoprotein (HDL) Function
HDL function is impaired in patients with type 2 diabetes mellitus. Anthocyanin, a water-soluble compounds,is beneficial for vascular function by increasing nitric oxide (NO) bioavailability and decreasing oxidative stress.
- Trial name
- NCT02650726
- Testing
- Anthocyanin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Exercise Training
Effect of Aronia Supplementation on the LPS-CD14-TLR2/4 Axis in Football Players
This randomized, double-blind, placebo-controlled trial will investigate the effects of 8-week Aronia melanocarpa supplementation on exercise-induced activation of the LPS-LBP-CD14-TLR2/TLR4 axis in trained male football players.
- Trial name
- ARONIA-TLR (NCT07829523)
- Testing
- Aronia melanocarpa Extract
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hanna Dziewiecka
Healthy Aging, Healthy
Investigating the Effects of Daily Consumption of Blueberry (Poly)Phenols on Vascular Function and Cognitive Performance
Foods rich in certain (poly)phenols, particularly flavonoids, such as berries and cocoa, have been shown to improve measures of vascular function as well as cognitive performance in human intervention studies.
- Trial name
- BluFlow (NCT04084457)
- Testing
- Wild Blueberry powder
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College London
Type 2 Diabetes
A Single Supplement of a Standardised Bilberry Extract Modifies Glycaemic Response
Dietary strategies for alleviating health complications associated with type 2 diabetes (T2D) are being pursued as alternatives to pharmaceutical interventions.
- Trial name
- NCT01245270
- Testing
- Bilberry capsule first, then control cap, Control capsule first then bilberry cap
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- University of Aberdeen
Diastolic Heart Failure, Hypertensive Heart Disease
Physiological Effects of Grape Seed Extract in Diastolic Heart Failure
Diastolic heart failure (also known as "heart failure with normal ejection fraction" or "heart failure with preserved ejection fraction") occurs even though the heart muscle's pumping function is normal.
- Conditions
- Diastolic Heart Failure, Hypertensive Heart Disease, Heart Failure With Preserved Ejection Fraction, Hypertension
- Trial name
- GRAPEVINE-HF (NCT01185067)
- Testing
- grape seed extract (MegaNatural BP, Polyphenolics, Inc.)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan