Clinical trials: Anti Oxidative Stress
Oxidative Stress, Infertility
Thiol/Disulphide Homeostasis in Unexplained Infertility
The aim in this study is to determine whether there is a relationship between Thiol / Disulphide levels in primary infertile patients and comparing them with infertile patients and the control group.
- Conditions
- Oxidative Stress, Infertility, Antioxidative Stress
- Trial name
- NCT05628766
- Testing
- complete blood count
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Siirt University
Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis. Objectives : 1.
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant
- Trial name
- NCT07089381
- Testing
- Resveratrol 1 gm., Methotrexate
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Metabolic Diseases, Immune System Disorder
Study on the Effects of Wheat and Corn Germ Blend Oil on Antioxidation and Immune Regulation of Dyslipidemia Population
The goal of this clinical trial is to explore the role of wheat and corn germ blended oils in regulating oxidative stress and immunomodulation in dyslipidaemic populations, to explore their effects on intestinal flora…
- Conditions
- Metabolic Diseases, Immune System Disorder, Dyslipidemias, Fatty Acid Metabolism Disorder
- Trial name
- NCT06060509
- Testing
- Phytosterol-rich Wheat and Corn Germ Blended Oil, Peanut oil
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Skin Manifestations, Antioxidative Stress
Omegia Softgel Clinical Research Program
Evaluate the improvement of regulation of skin and blood index composition after consumption of Omegia® Softgel
- Conditions
- Skin Manifestations, Antioxidative Stress, Eye Strain, Vaginal Disease
- Trial name
- NCT05872178
- Testing
- Omegia® Softgel -B, Omegia® Softgel -A
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Male Infertility With Severe Oligo-terato-asteno-spermia
Anti-oxidative Influence From Pomegranate Tablets on Male Sperm Quality in Couples Undergo Infertility Treatments Due to Male Infertility.
Some animal studies revealed that the pomegranate juice may improve sperm quality in terms of concentration, motility and morphology, as well as in fertilization rate. Minor data is available regarding the influence on male sperm.
- Trial name
- Pomegranate (NCT01918163)
- Testing
- Pomegranate pills
- Where
- Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Diabetes
Water-soluble Ubiquinol Supplementation on Blood Glucose, Lipids, Oxidative Stress, and Inflammation in Diabetes
Diabetes is considered an oxidative stress and a chronic inflammatory disease. Coenzyme Q10 (ubiquinone) is recognized as a lipid soluble antioxidant.
- Trial name
- NCT02622672
- Testing
- water-soluble ubiquinol
- Volunteers
- 50 people
- Sponsor
- Yeh
Oxidative Stress, Inflammation
Antioxidant and Anti-inflammatory Effects of Yogurt Enriched With Polyphenols
The purpose of this study is to investigate the possible antioxidant and anti-inflammatory effects of yogurt enriched with polyphenols after 2-week consumption by healthy individuals.
- Trial name
- NCT02494739
- Testing
- Yogurt enriched with polyphenols, Yogurt not enriched with polyphenols
- Where
- Greece
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Healthy
Evaluation of the Antioxidant and Anti-Inflammatory Capacities of the 'Rosy Red Valencia' and 'Olinda Valencia' Sweet Orange Varieties in Healthy Subjects
This study aims to evaluate the antioxidant and anti-inflammatory effects of acute and chronic consumption of two sweet orange (Citrus sinensis) varieties-'Rosy Red Valencia', which is rich in carotenoids such as lycopene…
- Trial name
- NCT06944210
- Testing
- 'Rosy Red Valencia' sweet orange, 'Olinda Valencia' sweet oranges
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Volunteer
Evaluation of Astaxanthin Properties on Anti-fatigue
Ten young, healthy, physically active male college students were crossed over for AST or placebo supplements randomized into placebo or AST trials and orally consumed placebo or AST (28 mg/d) supplements for four days.
- Trial name
- NCT06593535
- Testing
- Astaxanthin (AST trial)
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Early Renal Dysfunction in Diabetes, Diabetic Nephropathy
MMP-9/NGAL Modulation by Piper Crocatum in Early Diabetic Nephropathy
The goal of this clinical trial is to determine whether functional foods made with Piper crocatum (red betel leaf) can reduce kidney damage markers in people with diabetes who have early kidney dysfunction.
- Conditions
- Early Renal Dysfunction in Diabetes, Diabetic Nephropathy, Inflammation and Oxidative Stress in Diabetic Patients
- Trial name
- MMP-9/NGAL (NCT06676124)
- Testing
- Piper crocatum Extract Cookie
- Where
- Indonesia
- Volunteers
- 387 people
- Sponsor
- Hasanuddin University
Memory
Resveratrol for Improved Performance in the Elderly
The investigators aim to conduct a randomized placebo controlled pilot study to determine whether resveratrol, a dietary ingredient, supplementation is safe and improves memory and physical performance in older adults.
- Trial name
- RIPE (NCT01126229)
- Testing
- Low dose Resveratrol, High dose Resveratrol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Laparoscopic Appendectomy, Pain Management
Comparing N-Acetylcysteine (NAC) Versus Alpha-Lipoic Acid (ALA) as Adjuncts for Postoperative Pain Management After Laparoscopic Appendectomy
Postoperative pain remains a major concern following laparoscopic appendectomy, despite advances in minimally invasive surgery and multimodal analgesia.
- Conditions
- Laparoscopic Appendectomy, Pain Management, Anti Oxidative Stress
- Trial name
- NCT07360379
- Testing
- N Acetyl Cysteine, Alpha-Lipoic Acid (ALA)
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Metabolic Syndrome, Oxidative Stress
Impact of Pitavastatin in Hypercholesterolemic Patients With Metabolic Syndrome
The purpose of this study is to evaluate anti-oxidative and anti-inflammatory effects of pitavastatin in hypercholesterolemic patients with the metabolic syndrome.
- Conditions
- Metabolic Syndrome, Oxidative Stress, Inflammation
- Trial name
- NCT00444717
- Testing
- pitavastatin
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Aichi Gakuin University
Sickle Red Blood Cell, Fetal Hemoglobin
Effect of Broccoli Sprouts Homogenate on SS RBC
The overall purpose of this study is to obtain a better understanding of the biological response of red blood cells to sulforaphane contained in fresh broccoli sprouts that have been put through a blending process.
- Conditions
- Sickle Red Blood Cell, Fetal Hemoglobin, Oxidative Stress
- Trial name
- BSH (NCT01715480)
- Testing
- Broccosprouts® (Brassica Protection Products LLC) homogenate
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Duke University
Open-angle Glaucoma, Diabetic Retinopathy
Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy
This study is a multi-armed protocol designed to evaluate the safety and efficacy of two different combinations of nutritional supplements (study drug) (Glauco-Health and Glauco-Select) chosen for their potential to protect…
- Trial name
- NCT02984813
- Testing
- GlaucoHealth, GlaucoSelect
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The New York Eye & Ear Infirmary
Pulmonary Sarcoidosis
The Effect of N-Acetyl-L-Cysteine, on Inflammatory and Oxidative Stress Markers in Pulmonary Sarcoidosis
This is a pilot study investigating the effect of an antioxidant, N-Acetyl-L-Cysteine (NAC), on inflammation and oxidative stress in sarcoidosis.
- Trial name
- NCT01587001
- Testing
- N-acetyl-cysteine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Jewish Health
Cystic Fibrosis
Effect of Sulforaphane in Broccoli Sprouts on Nrf2 Activation
The purpose of this study to investigate the effect of sulforaphane from macerated broccoli sprouts in humans and to evaluate less invasive methods of assessing potential anti-inflammatory drugs in CF.
- Trial name
- NCT01315665
- Testing
- Broccoli sprouts
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Time Restricted Feeding, Overweight and Obesity
Clinical Trials of Effects of Time Restricted Eating on Health Parameters in Adults
In a randomized controlled trial we will research the effect of calorie restriction with early and mid-day time-restricted eating (TRE) and daily calorie restriction on weight loss and human health parameters.
- Conditions
- Time Restricted Feeding, Overweight and Obesity, Inflammation, Hypercholesterolemia
- Trial name
- TRE (NCT05730231)
- Testing
- Effects of calorie restriction and time-restricted eating on human health
- Where
- Slovenia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Skin Condition, Anti-Oxidative Stress
Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet
The objective of this study is to evaluate the effect of liquid vitamin C and glutathione supplements on human skin condition improvement and anti-oxidation.
- Trial name
- NCT07379216
- Testing
- Vitamin C and Glutathione Liquid Sachet
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
C-reactive Protein, Inflammation
Obesity, Inflammation and Oxidative Stress
The purpose of this study is to determine whether or not Vitamin C (1000 mg/day) can reduce markers of inflammation, especially C-reactive protein (CRP), in obese persons with baseline CRP greater than 1 mg/dl.
- Conditions
- C-reactive Protein, Inflammation, Obesity, Oxidative Stress
- Trial name
- NCT01028976
- Testing
- Vitamin C (ascorbic acid)
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley