Clinical trials: Anti-inflammatory Agents
Rheumatoid Arthritis, Osteoarthritis
Effect of Anti-inflammatory (ITIS) Diet in Rheumatoid Arthritis
to study the effect of anti-inflammatory diet on clinical and biological outcomes in rheumatoid arthritis
- Trial name
- NCT04999683
- Testing
- ITIS diet
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, San Diego
Asthma
Open-Label Trial of the Use of Minocycline in the Treatment of Asthma
The tetracycline minocycline has, in addition to its anti-infective properties, anti-inflammatory properties which may be of use in the treatment of asthma.
- Trial name
- NCT00536042
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- State University of New York - Downstate Medical Center
Arthritis, Rheumatoid
Comparing The Effectiveness And Safety Of 2 Doses Of An Experimental Drug, CP-690,550, To Methotrexate (MTX) In Patients With Rheumatoid Arthritis Who Have Not Previously Received MTX
This study is designed to compare the effectiveness of the experimental drug, CP-690,550, to methotrexate in preventing joint damage and improving symptoms of rheumatoid arthritis.
- Trial name
- ORAL1069 (NCT01039688)
- Testing
- CP-690,550, Disease-modifying antirheumatic drug
- Where
- 176 sites in United States, Argentina and 28 more
- Volunteers
- 956 people
- Sponsor
- Pfizer
Shoulder Pain, Injury of Shoulder Region
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure.
- Conditions
- Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff
- Trial name
- NCT01538459
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lifespan
Cancer, Cachexia
A Feasibility Study of Multimodal Exercise/Nutrition/Anti-inflammatory Treatment for Cachexia - the Pre-MENAC Study
A multicentre, open, randomized phase II study comparing a multimodal intervention (oral nutritional supplements, celecoxib and physical exercise) for cachexia versus standard cancer care.
- Trial name
- NCT01419145
- Testing
- Multimodal intervention, Standard care
- Where
- 3 sites in Norway, United Kingdom
- Volunteers
- 46 people
- Sponsor
- Norwegian University of Science and Technology
Osteoarthritis
Feasibility Study of Anti-inflammatory Cytokines in Whole Blood in Osteoarthritis Patients
This is a feasibility study to determine if anti-inflammatory cytokines can be concentrated from patients with osteoarthritis.
- Trial name
- NCT01050894
- Where
- 3 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Dermatitis, Atopic, Dermatitis
Effect of Benralizumab in Atopic Dermatitis
Atopic Dermatitis (AD), also known as eczema, is a common skin disease characterized by itchy lesions. The prevalence of AD has increased over the past few decades, with 15-30% of children and 2-10%of adults being affected.
- Conditions
- Dermatitis, Atopic, Dermatitis, Eczema, Skin Diseases
- Trial name
- NCT03563066
- Testing
- Benralizumab
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Gastric Ulcer, Duodenal Ulcer
Cytokine Gene Polymorphisms in Gastric Diseases
Recently, cytokine polymorphisms are considered to play an important role in the pathogenesis of peptic ulcer and gastric cancer.
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Gastric Cancer
- Trial name
- NCT00197470
- Testing
- IL-1, TNF-alpha, Il-10
- Where
- Japan
- Sponsor
- Hamamatsu University
Ankylosing Spondylitis, Axial Spondyloarthritis
Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis
This is a 6-week randomized, double-blind trial of 4 different non-steroidal anti-inflammatory drugs in patients with axial spondyloarthritis to compare the change of pain score from baseline at 4 weeks to the change of pain…
- Trial name
- NCT03473665
- Testing
- Indomethacin, Diclofenac, Meloxicam
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Columbia University
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Wet Macular Degeneration
Sub-tenon Triamcinolone Acetonide in Age-Related Macular Degeneration as Adjunct to Ranibizumab
In the Western World, Age Related Macular Degeneration (ARMD) is a leading cause of blindness. This disease was once thought to be a natural part of aging, but recent research has introduced effective treatments.
- Trial name
- STAR (NCT01249937)
- Testing
- Ranibizumab, Triamcinolone Acetonide
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Osteoarthritis
Anti-inflammatory Agents and Cholesterol Metabolism
We hypothesize that administration of anti-inflammatory medications such as celecoxib, naprosyn and diclofenac will cause changes in the blood plasma and white blood cells of patients such that they will be less able to…
- Trial name
- NCT01279395
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Winthrop University Hospital
Osteoarthritis, Arthritis, Rheumatoid
A Study of Rabeprazole for Prevention of Non Steroidal Anti-inflammatory Drug -Associated Gastroduodenal Injury
The aim of this study is to determine whether rabeprazole is superior to placebo in preventing dyspepsia and gastroduodenal injury in subjects with osteoarthritis (OA) and/or rheumatoid arthritis (RA) and/or bone pain.
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Dyspepsia
- Trial name
- NCT01140828
- Testing
- Rabeprazole
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Chinese University of Hong Kong
Chronic Kidney Disease
Ticagrelor and Anti-inflammatory Effects
Antiplatelet treatment in patients with end stage renal disease (ESRD) on hemodialysis (HD) is still challenging because of bleeding and thrombotic complications.
- Trial name
- NCT02406911
- Testing
- Ticagrelor
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Kyunghee University Medical Center
Crohn's Disease, Pediatric
Comparison of a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis
The primary purpose of this study is to compare the efficacy of enteral nutrition compared to steroids in inducing remission of active pediatric Crohn's disease.
- Trial name
- NCT00265772
- Testing
- MODULEN IBD (R) (specific Enteral Nutrition), prednisolon
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Hôpital Necker-Enfants Malades
Obstetric Pain
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
During labor there is an increased production of inflammatory mediators called cytokines. Higher concentration of certain cytokines has been linked to adverse neonatal and maternal outcomes.
- Trial name
- NCT00361712
- Testing
- Preemptive epidural analgesia, Standard of care
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Yellow Fever Vaccine, Yellow Fever
Yellow Fever Vaccine on Statin/ Non Statin Subjects
Since the 1st pandemic of the 21st century caused by SARS coronavirus, the world has experienced outbreaks of swine origin H1N1 influenza, Ebola and Zika viruses, which have all resulted in global health crises.
- Trial name
- NCT03116802
- Testing
- Stamaril (live attenuated yellow fever vaccine)
- Where
- Singapore
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Inflammation, Cardiovascular Risk Factor
Anti-Inflammatory Effect of Tocotrienol Supplementation in Subjects With Moderately Elevated Inflammation
The objective of this study is to address the anti-inflammatory effect of tocotrienol supplementation in subjects with moderately elevated inflammation.
- Trial name
- INTOC (NCT03532763)
- Testing
- Tocotrienol-rich fraction
- Where
- Malaysia
- Volunteers
- 180 people
- Sponsor
- Malaysia Palm Oil Board
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
The purpose of this study is to assess whether peri-procedural administration of rectal indomethacin, compared to placebo, can reduce the incidence of post-ERCP pancreatitis.
- Trial name
- NCT01774604
- Testing
- Indomethacin
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Alzheimer Disease
Multicenter Trial of Prednisone in Alzheimer's Disease
This is a randomized placebo controlled, double blind study. Patients who meet eligibility criteria and decide to participate in the study will be randomly assigned to receive either drug treatment or a placebo.
- Trial name
- NCT00000178
- Testing
- Prednisone
- Where
- 19 sites in United States
- Sponsor
- National Institute on Aging (NIA)
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