Clinical trials: Anti-inflammatory Agents
Parkinson's Disease
Radiation Therapy (RT) for Parkinson's Disease (PD)
The purpose of this study is to investigate the use of ultra-low, anti-inflammatory doses of radiation therapy (RT) for the treatment of Parkinson's Disease (PD).
- Trial name
- NCT07218952
- Testing
- Radiation therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Glaucoma
Steroids and/ or Non-steroidal Anti-inflammatory Drugs in the Postoperative Regime After Trabeculectomy.
PURPOSE: Glaucoma is the leading cause of non-curable blindness globally. Patients with glaucoma will get a gradual narrowing of the visual fields caused by compression at the optic nerve head due to increased intraocular…
- Trial name
- SNAP (NCT04054830)
- Testing
- Voltaren Ophtha 1 mg/ml, GSK, Monopex 1 mg/ml, Théa
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
HIV Infection
Pilot Study of Diflunisal in HIV-infected Adults
Diflunisal is an anti-inflammatory drug (like ASA or ibuprofen) that has been used as a painkiller for 20 years. Recent research shows that it may have an anti-HIV effect in the laboratory.
- Trial name
- NCT01676363
- Testing
- Diflunisal
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of British Columbia
Bronchopulmonary Dysplasia, Encephalomalacia
Randomized Trial of Hydrocortisone in Very Preterm High-Risk Infants
The purpose of this study is to determine whether treatment of very preterm infants at high-risk for lung and brain injury with low dose hydrocortisone results in improved pulmonary and neurologic outcomes.
- Conditions
- Bronchopulmonary Dysplasia, Encephalomalacia, Premature Birth
- Trial name
- NCT00167544
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Nationwide Children's Hospital
Osteoarthritis
Anti-inflammatory Effect of Serum of Osteoarthritis Patients After Administration of the Oléogrape®SEED, an Extract of Grape and Olive
Osteoarthritis is a degenerative disease that affects a growing proportion of the population. There is currently no treatment to halt this process.
- Trial name
- OléograpeSEED (NCT02566798)
- Testing
- Extract of grape and olive, Lactose
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Nantes University Hospital
PreDiabetes
Effects of Moringa Oleifera Leaves on Glycemia, Lipemia and Inflammatory Profile in Prediabetic Patients
Moringa oleifera (MO) is a traditional food in tropical and subtropical areas and has attained a growing interest for its medicinal properties. It's a nutrient-rich vegetable, high in protein and polyphenol content.
- Trial name
- NUTRIMOL-DB (NCT04734132)
- Testing
- Moringa
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Myocardial Infarction (MI)
Evaluating Metabolic and Anti-inflammatory Effect of Genistein on Post-myocardial Infarction Patients
The goal of this clinical trial is to learn if genistein works to provide a beneficial effect to show lipid lowering effect and anti-inflammatory effects and slow the progression of atherosclerosis in post-myocardial infarction…
- Trial name
- NCT06689566
- Testing
- genistein
- Where
- Taiwan
- Volunteers
- 73 people
- Sponsor
- National Taiwan University Hospital
Inflammation
Effects of Dietary Supplements on Response to Air Pollution
This study will determine if a comprehensive antioxidant/anti-inflammatory dietary supplement pack can offer protection against a decline in lung function and increase in inflammation and oxidative stress following acute exposure…
- Trial name
- NCT01488656
- Testing
- Antioxidant, anti-inflammatory dietary supplement
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Utah State University
Polyvascular Disease, Cardiovascular Disease
Anti-Inflammatory and Anti-Platelet Effect of Clopidogrel and Aspirin vs Aspirin Alone in Symptomatic Polyvascular Disease and in Patients With Multiple Recurrent Cardiovascular Events
This is a monocentric, randomized, opened study to assess the anti-inflammatory and anti-platelet effect of Clopidogrel and aspirin versus aspirin or clopidogrel alone in patients with symptomatic polyvascular disease and with…
- Trial name
- NCT00775762
- Testing
- aspirin, clopidogrel, clopidogrel plus aspirin
- Where
- Italy
- Volunteers
- 213 people
- Sponsor
- Catholic University of the Sacred Heart
Schizophrenia
Anti-inflammatories and Adolescent Schizophrenia
A double-blind controlled trial assessing the efficacy of anti-inflammatories on symptoms and cognition of adolescents with schizophrenia
- Trial name
- NCT04020588
- Testing
- Celecoxib 200mg, Minocycline 100mg
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Hospital Psiquiatrico Infantil Dr. Juan N. Navarro, Mexico
Multiple Sclerosis, Relapsing-Remitting
Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis
Multiple sclerosis (MS) is an inflammatory autoimmune disease associated with an imbalance between pro- and anti-inflammatory markers (cytokines) resulting in a demyelinating and neurodegenerative disease.
- Trial name
- NCT04972929
- Testing
- Spinal Manipulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Alabama at Birmingham
Chronic Kidney Disease, Inflammation
Anti-Inflammatory Effects of Rosiglitazone in Patients With Stage 4 and 5 Chronic Kidney Disease
The purpose of this study in patients with stage 4 and 5 chronic kidney disease is to determine whether rosiglitazone can reduce inflammatory markers and to investigate its effect on intima media thickness, calcification and…
- Trial name
- Hercules (NCT00169923)
- Testing
- rosiglitazone
- Where
- 2 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Leiden University Medical Center
Postoperative Ileus
Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve
Hypothesis: Electrical stimulation of the abdominal vagus nerve has anti-inflammatory effects which lead to a faster postoperative recovery after abdominal surgery.
- Trial name
- NCT02524626
- Testing
- Vagus stimulation
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- KU Leuven
Chronic Lung Disease
The Anti-inflammatory Effect of Prophylactic Macrolides on Children With Chronic Lung Disease
The purpose of this study is to determine if the prophylactic use of azithromycin will reduce the total number of days when unscheduled treatment is given outside of the home in a clinic, urgent care, emergency room or hospital…
- Trial name
- NCT02544984
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Periodontitis, Diabetes Type 2
Effect of Periodontal Therapy in the Systemic Status of Individuals With Chronic Periodontitis and Diabetes Type 2
This study will evaluate if periodontal mechanical treatment is capable to alter immunological and genetical parameters related to systemic health in patients with chronic periodontitis ant diabetes type 2.
- Trial name
- NCT02589314
- Testing
- Mechanical periodontal therapy, nonsurgical periodontal therapy
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Irreversible Pulpitis, Post-endodontic Pain
Comparative Evaluation of Diclofenac Sodium and Ibuprofen for Post-Endodontic Pain Management
This randomized controlled trial aims to compare the effectiveness of Diclofenac sodium and Ibuprofen in reducing pain after root canal treatment.
- Conditions
- Irreversible Pulpitis, Post-endodontic Pain, Root Canal Treatment
- Trial name
- DIPI-PEP (NCT07565012)
- Testing
- Ibuprofen, Diclofenac sodium
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Human Nutrition, Omega-3 Fatty Acids, Microalgae, Micronutrients
"Health Promoting Effects of the Microalgae Phaeodactylum Tricornutum"
The aim of the research project is to investigate the uptake of omega-3 fatty acids into the blood plasma through the consumption of the microalgae Phaeodactylum tricornutum (PT) in a human study.
- Trial name
- UniHoh-Algen (NCT04288544)
- Testing
- Microalgae, Omega-3-fatty acid capsule, sea fish
- Where
- 2 sites in Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Liver Transplant; Complications, Infections
Inflammatory and Anti-Inflammatory Gene Expressions in Liver Transplant Patients
In our study, some inflammatory Interleukin-2 , Interleukin-6, Interferon-γ, Tumor Necrosis Factor-α and anti-inflammatory Interleukin-4 and Interleukin-10 cytokine genes expressions and Triggering Receptor Expressed On Myeloid…
- Conditions
- Liver Transplant; Complications, Infections, Gene Amplification, Immune Response
- Trial name
- NCT05852964
- Testing
- Molecular Immunology , gene expressions
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pain, Quality of Life
Evaluation of the Effects of Different Analgesics on Pericoronitis Pain and Quality of Life
Pericoronitis is a painful inflammatory condition which is well known for its negative impact on quality of life of those affected.
- Trial name
- NCT03745599
- Testing
- Diclofenac, Flurbiprofen, Benzydamine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Near East University, Turkey
Gingivitis
Clinical Evaluation and Assesment of Ginigivitis Patients Treated by Yarrow Natural Extract in Compare to a Contro Group
A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry…
- Trial name
- NCT06070571
- Testing
- Yarrow and moringa mixture
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Deraya University
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