Clinical trials: Antibiotic Resistance, Microbial
Antibiotic Resistance, Ocular Surface Microbiome
Antibiotic Resistance In Eye Surgeries
In this study, the investigators seek to determine the effect of antibiotic use post-surgery on antimicrobial resistance. The investigators will be studying adults (aged 18 or older) who will undergo eye surgery at University of…
- Conditions
- Antibiotic Resistance, Ocular Surface Microbiome, Gut Resistome
- Trial name
- ARIES (NCT04750655)
- Testing
- Moxifloxacin (Topical)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of California, San Francisco
Periodontitis
Long-term Safety of Minocycline in Patients With Gum Disease
This study will look at the safety of using the study medicine for a long time. It will see if the germs get used to the medicine, making it not work as well, if it's used by people with gum disease for a long time.
- Trial name
- NCT00668746
- Testing
- Minocycline HCl microspheres
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- OraPharma
Pneumonia
Detection of Microorganisms and Antibiotic Resistance Genes Using the Curetis Unyvero LRT55 Application
The Curetis Unyvero LRT55 Application is intended to detect and to identify genes of 21 microorganisms and 19 genes associated with antibiotic resistance in 4 hours.
- Trial name
- LRT55 (NCT01922024)
- Testing
- LRT55 Testing
- Where
- 9 sites in United States
- Volunteers
- 2,124 people
- Sponsor
- Curetis GmbH
Methicillin-resistant Staphylococcus Aureus
Project CLEAR - Changing Lives by Eradicating Antibiotic Resistance
This randomized controlled trial will compare strategies to reduce the risk of methicillin-resistant Staphylococcus aureus (MRSA) infection and re-hospitalization in MRSA carriers.
- Trial name
- CLEAR (NCT01209234)
- Testing
- Standard-of-Care Education, MRSA Decolonization
- Where
- 24 sites in United States
- Volunteers
- 2,140 people
- Sponsor
- University of California, Irvine
Periapical Abscess
"Is Antibiotic Therapy Necessary for Patients Undergoing Extraction of Teeth With Abscess?"
This is a triple-blind randomized controlled trial conducted at the Department of Oral and Maxillofacial Surgery, Subbaiah Institute of Dental Sciences, Shimoga.
- Trial name
- NCT07694531
- Testing
- Amoxicillin 500mg
- Where
- India
- Volunteers
- 176 people
- Sponsor
- Subbaiah Institute of Dental Sciences
Acute Otitis Media
Reduced Clavulanate Formulation of Amoxicillin-Clavulanate in Children 6-23 Months With Acute Otitis Media
To evaluate the safety profile of amoxicillin-clavulanate potassium containing a reduced concentration of clavulanate potassium, 600 mg/21.5 mg/5 mL (a ratio of 28:1), administered at 90/3.2 mg/kg/day (formulation 1) or at…
- Trial name
- NCT02630992
- Testing
- Amoxicillin-Clavulanate potassium
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Nader Shaikh
Infection With Multi-drug Resistant Organisms
FMT for Multidrug Resistant Organism Reversal
This proposed protocol involves the use of the fecal microbiota transplantation (FMT) to suppress or reverse colonization with multidrug resistant organisms (MDRO) in subjects with recurrent MDRO infections due to organisms of…
- Trial name
- NCT02312986
- Testing
- Fecal microbiota transplantation (FMT)
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine
Antibiotic Resistant Strain
A Trial of Encapsulated Fecal Microbiota for Vancomycin Resistant Enterococcus Decolonization
The objective of this study is to provide preliminary insight into the safety and efficacy of fecal microbiota transplantation (FMT) for the eradication of gastrointestinal carriage of vancomycin-resistant Enterococcus.
- Trial name
- NCT03063437
- Testing
- Encapsulated fecal microbiota preparation
- Where
- 2 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Microbiome Health Research Institute
Child Development
Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso
The use of antibiotics has saved millions of human lives, however consumption of antibiotics can select for antibiotic resistant organisms and may lead to changes in commensal microbiome.
- Trial name
- ARMCA (NCT03187834)
- Testing
- Azithromycin, Amoxicillin, Cotrimoxazole
- Where
- 2 sites in United States, Burkina Faso
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Childhood Mortality
Mortality Reduction After Oral Azithromycin: Mortality Study
Our long-term goal is to more precisely define the role of mass azithromycin treatments as an intervention for reducing childhood mortality.
- Trial name
- MORDORIMort (NCT02047981)
- Testing
- Azithromycin
- Where
- 6 sites in United States, Malawi and 3 more
- Volunteers
- 190,238 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vesicoureteral Reflux, Urinary Tract Infections
Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)
In this 2-year, multisite, randomized, placebo-controlled trial involving 607 children with vesicoureteral reflux that was diagnosed after a first or second febrile or symptomatic urinary tract infecton, we evaluated the efficacy…
- Trial name
- RIVUR (NCT00405704)
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- 19 sites in United States
- Volunteers
- 607 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Antibiotic Resistant Infection, Nosocomial Infection
Inulin for Infections in the Intensive Care Unit
Normal gut bacteria prevent colonization and subsequent infection with MDR organisms (MDROs) through competition for resources and other mechanisms.
- Conditions
- Antibiotic Resistant Infection, Nosocomial Infection, Pathogen Transmission, Nutrition Disorders
- Trial name
- NCT03865706
- Testing
- Inulin Oral Suspension, Broad-spectrum antibiotics
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Columbia University
Infection
Antibiotic Prophylaxis for Transrectal Prostate Biopsy
This study is being conducted in men scheduled to undergo transrectal ultrasound-guided prostate biopsy (TRUSP). Traditionally prior to prostate biopsy, an antibiotic, ciprofloxacin, has been given to men to prevent…
- Trial name
- NCT01659866
- Testing
- Ciprofloxacin, trimethoprim-sulfamethoxazole, cefuroxime
- Where
- United States
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Northwestern University