Clinical trials: Antibiotic Treatment
Stage III Periodontitis
Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management
To better understand and treat your gum disease, dentists now use a system that stages its severity and grades its speed, rather than using old labels.
- Trial name
- NCT07316023
- Testing
- Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded nanoparticles, Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded macroparticles, Non- surgical periodontal therapy only
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Nada Mahmoud Soliman
Anaplastic Large Cell Lymphoma
SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma
This phase II trial is studying how well giving SGN-30 together with combination chemotherapy works in treating patients with newly diagnosed anaplastic large cell lymphoma.
- Trial name
- NCT00365274
- Testing
- Cyclophosphamide, Doxorubicin hydrochloride, vincristine sulfate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Cancer Institute (NCI)
Periodontal Disease, Periodontal Disease Stage 2
ABX Versus CHX in NSPT
The study aims to compare the efficacy of a novel mouthwash based on microRepair ABX and an antibacterial complex with that of 0.12% chlorhexidine, both used as adjuncts to scaling and root planing.
- Conditions
- Periodontal Disease, Periodontal Disease Stage 2, Periodontal Disease, AVDC Stage 3
- Trial name
- ABXvsCHX (NCT07520968)
- Testing
- ABX Mouthwash as adjunctive to non surgical periodontal treatment, CHX as adjunctive to non surgical periodontal treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Community-acquired Pneumonia
Shortened Antibiotic Treatment of 5 Days in Community-Acquired Pneumonia
CAP5 is an investigator-initiated multicentre non-inferiority randomized controlled trial which aims to assess the efficacy and safety of shortened antibiotic treatment duration of community-acquired pneumonia (CAP) in…
- Trial name
- CAP5 (NCT04089787)
- Testing
- Intervention, Control
- Where
- 7 sites in Denmark
- Volunteers
- 395 people
- Sponsor
- Thomas Benfield
Staphylococcal Skin Infections, Streptococcal Infections
A Single-Dose Pharmacokinetics and Safety Study of Ceftobiprole in Pediatric Patients =3 Months to <18 Years of Age
This study will assess the pharmacokinetics (how drugs are absorbed, distributed in the body and removed over time) and safety of a single dose of ceftobiprole in pediatric patients undergoing treatment with systemic antibiotics…
- Trial name
- NCT01026636
- Testing
- Ceftobiprole
- Volunteers
- 64 people
- Sponsor
- Basilea Pharmaceutica
Ulcerative Colitis
Trial of Antimicrobials Versus Placebo in Addition to Fecal Transplant Therapy in Ulcerative Colitis
The investigators will test the hypothesis that giving antibiotics prior to fecal transplant therapy for active UC increases the proportion of patients in remission at the end of treatment.
- Trial name
- FMT (NCT02606032)
- Testing
- Metronidazole, Doxycycline, Terbinafine
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Hamilton Health Sciences Corporation
Endodontic Disease, Root Canal Infection
Comparison of Antibacterial Efficacy of Three Final Irrigants
This study was conducted to determine the antibacterial affect of three different solutions used as final irrigant during endodontic therapy.
- Trial name
- NCT03853200
- Testing
- QMix Root Canal Irrigant, 17%EDTA+2%Chlorhexidine, EDTA
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Helicobacter Pylori Infection
Auto Fecal Microbial Transplant Post Helicobacter Pylori Antibiotic Therapy
Current guidelines mandate Helicobacter pylori (H. Pylori) eradication with 2-3 antibiotics for 14 days ,This may result in multiple side effects and in eradication of important bacterial species to human health, exposing humans…
- Trial name
- NCT05329636
- Testing
- Fecal Microbial Transplant (FMT), Auto Fecal Microbial Transplant (FMT) via enema
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Dyspepsia, Peptic Ulcer
Amoxicillin/Metronidazole Based Quadruple Therapy for Helicobacter Pylori Eradication
No trial has examined the the efficacy of amoxicillin and metronidazole based quadruple therapy for Helicobacter pylori treatment.
- Trial name
- NCT02175901
- Testing
- Lansoprazole, Bismuth Potassium Citrate, Amoxicillin
- Where
- China
- Volunteers
- 215 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Healthy Volunteers
The Immunostimulatory Effects of Gentamicin
Gentamicin is one of the few aminoglycoside antibiotics which are approved for parenteral use in Singapore. As with other aminoglycosides, gentamicin is primarily bactericidal against Gram-negative organisms.
- Trial name
- NCT05303909
- Testing
- Gentamicin
- Where
- Singapore
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Endocarditis, Bacterial
Short-course Antibiotic Treatment in Gram-positive Cocci Infective Endocarditis
Background: it is well known that most serious complications of infective endocarditis (IE) appear in the so-called "critical phase" of the disease, which are the first days after diagnosis.
- Trial name
- SATIE (NCT04222257)
- Testing
- Antibiotics
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Carmen Olmos Blanco
Acute Wounds
Efficacy Study of a New Antimicrobial Wound Dressing to Treat Wounds Caused by Curettage and Electrodesiccation
The purpose of this pilot clinical study is to compare healing rates, pain levels, and incidence of wound complications including infection with the use of a moist PROCELLERA™ Antimicrobial Wound Dressing when compared to a…
- Trial name
- NCT00816101
- Testing
- Procellera™ Antimicrobial Dressing, Mepilex® Border Lite, Adhesive Bandage
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Vomaris Innovations
Periodontal Diseases, Smoking
Clinical Evaluation of Smoker Periodontal Subjects After Lactobacillus-reuteri Probiotics and Antibiotics Therapy
It is a clinical trial conducted on smokers with chronic periodontitis in which the participants are divided into two groups and one group is provided with antibiotics while the other with probiotics as an adjunct to non-surgical…
- Trial name
- NCT04209777
- Testing
- Probiotic Blend Chewable Tablet, Antibiotics
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pyelonephritis Acute
3-day IV Antibiotic Treatment Versus 3-day IV Followed by 7-day Oral Antibiotic Treatment for AP in Children
Antibiotic therapies currently recommended for the treatment of acute pyelonephritis (AP) in children, whether fully by the oral route or initially intravenous (IV, 3 days) followed by the oral route, have a duration of 7 to 14…
- Trial name
- PYELOCOURT (NCT05544565)
- Testing
- IV Antibacterial Agents, Orally antibacterial agents, Fecal/Rectal Swab
- Where
- 15 sites in France
- Volunteers
- 480 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Wall Prosthesis Infections
Early Abdominal Wall Prosthesis Infections: Epidemiology, Risk Factors and Factors Linked to Recovery
Abdominal wall prosthesis infections are among the complications most feared by digestive surgeons. Indeed, this complication is associated with high morbidity and is difficult to manage (antibiotic therapy? surgical revision?).
- Trial name
- AWPI (NCT06498245)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Cholangitis, Secondary Biliary, Treatment Compliance
Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy
Application of multi-center, prospective study on the severity of postoperative cholangitis biliary atresia classification, according to the degree of cholangitis targeted therapy, to improve the therapeutic effect of…
- Conditions
- Cholangitis, Secondary Biliary, Treatment Compliance, Antibodies Drug Specific
- Trial name
- NCT04370145
- Testing
- Sulperazon, Teicoplanin, Meropenem Injection
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Tongji Hospital
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Overactive Bladder (OAB), Urinary Tract Infection (Diagnosis)
Methenamine Hippurate Following Intradetrusor OnabotulinumtoxinA Injection
The goal of this clinical trial is to compare methenamine hippurate prophylaxis to routine antibiotic prophylaxis following onabotulinumtoxinA (BOTOX-A) injections in women with overactive bladder (OAB).
- Trial name
- META (NCT06953271)
- Testing
- Methenamine Hippurate, Typically prescribed oral antibiotic prophylaxis
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Quality of Life, Infection, Bacterial
Retrospective Chart Review of Treataprost Added to Antibiotic Treatment in Patients With Chronic Prostatitis
Multicenter, Retrospectivecohort study in patients with Chronic Prostatitis, Chronic Bacterial Prostatitis (Category II) and Chronic Pelvic Pain Syndrome (Category IIIA, IIIB) and 140 patients without other significant…
- Conditions
- Quality of Life, Infection, Bacterial, PSA, Prostatitis
- Trial name
- Treataprost (NCT05306314)
- Testing
- TREATAPROST
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- GMG Grand Medical
Gastritis, Indigestion, Helicobacter Pylori Infection, Gastric Cancer, Peptic Ulcer
Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradication: A Prospective, Randomized Controlled Clinical Trial
This study aims to evaluate the efficacy of vonoprazan combined with different antibiotics in dual therapy for Helicobacter pylori eradication treatment.
- Trial name
- NCT07068607
- Testing
- Vonoprazan, Tetracycline 500mg tid, Minocycline
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yongquan Shi