Clinical trials: Antioxidants
Hard-to-heal Wounds
Evaluation of the Efficacy of an Antioxidant Dressing in Chronic Wound Healing
The aim of this study is to compare the effect of antioxidant dressing (active product) on chronic wound healing with the use of non-active wound dressing for healing in a moist environment (standard clinical practice) in…
- Trial name
- REOX (NCT03934671)
- Testing
- Antioxidant dressing (active product), Usual care dressing that create a moist environment (standard clinical practice)
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- University of Jaén
Coronary Artery Disease
L-carnitine and Coenzyme Q10 in Relation to the Oxidative Stress, Antioxidant Enzymes Activities, Inflammation, and the Risk of Coronary Artery Disease
Cardiovascular disease (CVD) is the leading cause of Taiwan. L-carnitine (LC) and coenzyme Q10 is recognized as lipid soluble antioxidants.
- Trial name
- NCT01819701
- Testing
- LC-1000, LC-2000, Q10-150
- Where
- Taiwan
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Contribution of Ethanol on Hydroxytyrosol Formation
Relevance of the Ethanol Dose in the Generation of Endogenous Hydroxytyrosol
Health benefits for humans derived from low dose intake of ethanol could partially be explained by its interaction with dopamine (DA) oxidative metabolism.
- Trial name
- NCT01788670
- Testing
- Ethanol, Water
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Menopause, Nutritional Intervention
Short-term Supplementation, Bone Turnover and Antioxidant Status in Menopause
This is a 8-week, double-blinded, placebo-controlled, randomized intervention trial to investigate the effects of Mg and Zn supplementation on antioxidant status and bone hormonal parameters.
- Conditions
- Menopause, Nutritional Intervention, Bone Diseases
- Trial name
- NCT03672513
- Testing
- Zinc Supplement, Magnesium supplement
- Where
- Spain
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Diabetic Retinopathy
Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy
The present study aims to support previous research on antioxidant therapy effects in diabetic retinopathy outcome. The investigators intend to assess 180 patients with diabetic retinopathy in different stages (moderate, severe…
- Trial name
- NCT03702374
- Testing
- Combined antioxidant therapy
- Where
- Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Pneumonia, Viral, Covid19
Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19
Introduction: SARS-CoV2 infection produces severe pneumonia with pulmonary alveolar collapse. There is no specific treatment to date.
- Conditions
- Pneumonia, Viral, Covid19, ARDS, Oxidative Stress
- Trial name
- ANTIOX-COVID (NCT04570254)
- Testing
- Vitamin C, Vitamin E, Melatonin
- Where
- Mexico
- Volunteers
- 110 people
- Sponsor
- Unidad Temporal COVID-19 en Centro Citibanamex
H Pylori Gastritis, H Pylori Infection
Efficacy of Carminal in Helicobacter Pylori Gastritis
Eighty patients will be included and randomized in two groups, one group (40 patients) will be administered 30 ml of the supplement Carminal, once a day, plus therapy for HP gastitis and the control group (40 patients) will be…
- Conditions
- H Pylori Gastritis, H Pylori Infection, H Pylori Eradication, Gastritis Associated With Helicobacter Pylori
- Trial name
- NCT07179237
- Testing
- Carminal Oral solution
- Where
- 2 sites in Serbia
- Volunteers
- 80 people
- Sponsor
- Catalysis SL
Gynecologic Laparoscopic Surgery
COMPARISON OF OXIDANT-ANTIOXIDANT LEVELS WITH STRESS HORMONES IN SPINAL ANESTHESIA AND GENERAL ANESTHESIA IN LAPAROSCOPIC TUBE LIGATION
The aim of this observational study is to investigate the effect of anesthesia method applied in laparoscopic tubal ligation on stress factors in women aged 15-45.
- Trial name
- LAP TUBE LİG (NCT06710522)
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- KADİR TEOMAN
Autosomal Dominant Polycystic Kidney Disease
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
The purpose of this study is to characterize oxidative stress and the Nrf2 antioxidant response in early stages of Autosomal Dominant Polycystic Kidney Disease (ADPKD), while identifying candidate biomarkers.
- Trial name
- NCT04344769
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiovascular Diseases
Hypolipidemic and Antioxidant Capacity of Spirulina and Exercise
The purpose of this study is to demonstrate that Spirulina maxima intake and a dosed physical activity program will decrease, both independently and synergistically, cardiovascular risks (Dyslipidemias and oxidative stress) in…
- Trial name
- NCT02837666
- Testing
- Supplementation with Spirulina maxima, Washout, Isoenergetic diet
- Where
- Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Essential Hypertension
Study MIPAE - Melatonin and Essential Arterial Hypertension
Study MIPAE - Melatonin and essential arterial hypertension. Study with dietary supplement, prospective and monocentric (randomized control trial).
- Trial name
- MIPAE (NCT05257291)
- Testing
- Melatonin
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Kidney Calculi
Are There Protective Effects of Antioxidants, Calcium Channel Blocker and Angiotensin Receptor Blocker Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury?
This study will be conducted to evaluate the protective effects and mechanisms of antioxidants (vitamins A, C, E and Selenium), calcium channel blocker (Verapamil) and angiotensin receptor blocker (Lozartan) against shock wave…
- Trial name
- SWL (NCT01675362)
- Testing
- Antioxidant group, Calcium Channel Blockers, Angiotensin receptor blocker group
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Coronary Artery Disease
Effect of Grape Seed Extract Plus Ascorbic Acid on Endothelial Function
A pilot study of 15 subjects will be conducted to confirm an acute effect of grape seed extract on endothelial function. We then will perform a a randomized, double blind, placebo controlled crossover study designed to…
- Trial name
- NCT00554242
- Testing
- Grape seed extract and ascorbic acid
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston University
Stress Oxidative
Natural Antioxidant Intake After Exercise Can Oxidative Stress in the Third Trimester of Pragnancy
Pregnancy is a condition that increased requirements of energy and oxygen, and if this condition is not maximally that can lead oxidative stress and produce free radicals which is affect in the pregnancy process.
- Trial name
- MDA (NCT04226183)
- Testing
- pregnancy workout
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Heart Failure, Sleep Disorders
Melatonin Supplementation to Improve Sleep in Patients With Heart Failure
The purpose of this study is to determine whether melatonin can improve sleep, quality of life and markers of heart failure in patients with heart failure.
- Trial name
- NCT00869869
- Testing
- melatonin
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Hypertension, Hypercholesterolemia
Effects of Purple Vegetables on Cardiovascular Disease (CVD) Risk Factors
The hypothesis is that richly coloured purple vegetables, rich in polyphenolic compounds including anthocyanins will have higher antioxidant and other biological activities, than more lightly coloured versions of these foods.
- Conditions
- Hypertension, Hypercholesterolemia, Type II Diabetes, Obesity
- Trial name
- NCT01564498
- Testing
- vegetable
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Guelph
Dietary Supplement, Cognition
Nutritional Supplement's Effects on Cognition
This is a prospective, placebo controlled study, examining the effects of dietary supplement's effects on cognition and confirming safety.
- Conditions
- Dietary Supplement, Cognition, Healthy
- Trial name
- NCT05941949
- Testing
- Softgel Cognitive Formulation containing Astaxanthin, Grape Juice Extract and All Natural Vitamin E
- Where
- Australia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Brain Aging
Milk Intervention Study for Brain Aging
The purpose of this study is to learn if increased dairy food consumption helps brain health in older adults by protecting nerve cells from damage.
- Trial name
- NCT02957422
- Testing
- 1% Milk, Control
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Celiac Disease
The Effect of Unripe Carob Fruit in Celiac Patients
The aim of this study was to investigate the effects of the consumption of cookies produced by adding the unripe part of carob fruit, which has high insoluble fiber, polyphenol and antioxidant content, on the oxidative parameters…
- Trial name
- NCT06300164
- Testing
- Unripre Carob
- Volunteers
- 30 people
- Sponsor
- Toros University
Autism Spectrum Disorder, Autism
GAIP ASD Research Study
This clinical research study evaluates the safety and preliminary effects of AdiaVita (umbilical cord blood-derived stem cells and exosomes) combined with glutathione versus glutathione alone in people aged 3 and older with…
- Conditions
- Autism Spectrum Disorder, Autism, ASD, Autism Spectrum Disorder (ASD)
- Trial name
- NCT07622316
- Testing
- Umbilical Cord Blood-Derived Stem Cells and Exosomes, Glutathione
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Greater Atlanta Integrative Pediatrics