Clinical trials: Antioxidants
Cerebral Stroke, Malondialdehyde
Effect of Astaxanthin Supplementation on Plasma Malondialdehyde Levels and NIHSS of Stroke Patients
This is an interventional randomized, controlled trial in analyzing the effects of astaxanthin supplementation on plasma malondialdehyde levels and NIHSS of acute ischemic stroke patients.
- Conditions
- Cerebral Stroke, Malondialdehyde, Oxidative Stress
- Trial name
- NCT03945526
- Testing
- Astaxanthine
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Universitas Indonesia
Acute Myocardial Infarction, Ischemia-reperfusion Injury
Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.
Background: Acute myocardial infarction (AMI) has remained a leading cause of mortality and disability worldwide. Although percutaneous coronary angioplasty (PCA) is the best treatment for these patients, paradoxically this…
- Conditions
- Acute Myocardial Infarction, Ischemia-reperfusion Injury, Reperfusion Injury, Myocardial, Reperfusion Arrhythmias
- Trial name
- NCT05215743
- Testing
- Antioxidant therapy, NaCl 0.9%
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Chile
Healthy
Safety of Ginkgo Biloba Leaf Extract
Primary objective: The primary objective of this study is to assess the effect of Ginkgo biloba L. leaf extract (IDN 5933) in comparison to placebo in human subjects treated at therapeutic doses for 6 months on the level of DNA…
- Trial name
- GiBiEx (NCT03004508)
- Testing
- Gingko Biloba Extract
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- IRCCS San Raffaele
Preoperative Care, Antioxidants
Palatability of Antioxidant Biscuits
Patients who are due to have planned bowel surgery will be invited to take part in the study. Those that consent, will be given a 5 day supply of 'Fitabisc' (a biscuit designed to have the potential to provide nutritional…
- Trial name
- Fitabisc2 (NCT04027504)
- Testing
- Fitabisc
- Where
- United Kingdom
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Chronic Spontaneous Urticaria (CSU)
Effects of Diet and Oxidative Stress on Disease Severity and Response to Omalizumab in Chronic Spontaneous Urticaria
Chronic spontaneous urticaria (CSU) is an immune-mediated skin disorder characterized by pruritic wheals and/or angioedema. This study aims to evaluate the relationship between diet-derived antioxidant capacity and oxidative…
- Trial name
- NCT07431658
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Breast Neoplasm, Breast Cancer
Effect of a Clinical Nutrition Intervention Program in Breast Cancer Patients During Antineoplastic Treatment
The aim of this study is to evaluate the effect of a 6-mo individualized and specialized food-based nutrition intervention program in breast cancer patients' body composition, metabolism and antioxidant activity associated with…
- Trial name
- NCT03625635
- Testing
- Individualized food-based intervention
- Where
- Mexico
- Volunteers
- 34 people
- Sponsor
- Humberto Francisco Astiazaran Garcia, PhD
Friedreich Ataxia
Safety Study of Idebenone to Treat Friedreich's Ataxia
This study will determine the highest dose of idebonone that can safely be given to patients with Friedrich's ataxia, an inherited degenerative disease that causes loss of muscle coordination, speech problems, weakness and…
- Trial name
- NCT00015808
- Testing
- Idebenone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Atopic Asthma
Randomized Controlled Trial of Silymarin in Asthma
The purpose of this study is to determine if intake of the antioxidant enzyme inducer, silymarin, will improve lung function and symptom scores in participants with asthma.
- Trial name
- NCT01049178
- Testing
- Oral Silymarin, Oral Silymarin, maintenance dose
- Where
- United States
- Sponsor
- Vanderbilt University
Pressure Sores, Intensive Care
The Effect of Antioxidants on the Immune Response and Wound Healing in Critically Ill Patients
The purpose of this study is to investigate whether the addition of omega-3 and antioxidants to nutritional support in critically ill patients in the intensive care unit influences the immune and anti-inflammatory systems and so…
- Trial name
- NCT00487097
- Testing
- Eicosapentanoic acid, docosahexaenoic acid
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
Lung Diseases
Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air
This work will focus on the anti-inflammatory and antioxidant pathways in lung diseases by measuring HO-1 in induced sputum and CO in exhaled air in cases of four respiratory diseases, asthma, chronic obstructive pulmonary…
- Trial name
- NCT01140685
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Breast Neoplasms
The Impact of Chronic Mitochondrial Antioxidant Supplementation on CardiovascularToxicity in Breast Cancer Patients
Investigate the protective effect of chronic MitoQ supplementation on cardiovascular toxicity induced by doxorubicin-based adjuvant chemotherapy in breast cancer patients.
- Trial name
- NCT05146843
- Testing
- Mitoquinone
- Volunteers
- 44 people
- Sponsor
- D'Or Institute for Research and Education
Healthy
Acute Effect of Functional Crackers on Postprandial Metabolism
The aim of this interventional study was to investigate the postprandial effect of two types of functional crackers, with 10% grape seed flour or 40% barley flour, enriched with β-glucan, in metabolic biomarkers of healthy…
- Trial name
- Crade23 (NCT05977543)
- Testing
- Functional crackers enriched with grape seed flour, Functional crackers with 40% barley flour and enriched with β-glucans
- Where
- Greece
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of the Aegean
Exercise-induced Oxidative Stress
Physiological Effect of Ataulfo Mango (Manguifera Indica) Beverage in Exercise
The aim of this study is to assess the antioxidant capacity of two mango base beverages (AM1, AM2), against exercise-induced oxidative stress.
- Trial name
- NCT03182543
- Testing
- Mango pulp beverage, Mango pulp and peel beverage, Control beverage
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Mothers, Lactation
Effect of Intracellular Content From Lactobacillus Casei CRL-431 on Antioxidant Capacity of Breast Milk
The objective of the present study was to evaluate the effect of the consumption of the intracellular content of Lactobacillus casei CRL-431 on the antioxidant capacity of breast milk
- Trial name
- NCT04335708
- Testing
- Postibiotic formulation
- Where
- Mexico
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Centro de Investigación en Alimentación y Desarrollo A.C.
Female, Infertility
The Effect of Ovamax on Oocyte Quality
Oocyte quality is a basic parameter that affects embryo quality and therefore it influences the outcome of assisted reproduction. It has been suggested that oocyte quality is improved by the intake of vitamins and antioxidants.
- Trial name
- NCT06203223
- Testing
- Ova-max
- Where
- Greece
- Volunteers
- 97 people
- Sponsor
- Aristotle University Of Thessaloniki
Oxidative Stress, Endothelial Function
Effect of Tahini in Oxidative Stress and Endothelial Function in Diabetes
Cardiovascular disease (CVD), a cluster of disorders that affect heart and blood vessels, is the leading cause of morbidity and mortality around the world and is responsible for 17.9 million deaths annually worldwide.
- Conditions
- Oxidative Stress, Endothelial Function, Blood Pressure, Arterial Stiffness
- Trial name
- NCT05396079
- Testing
- tahini and bread, margarine, cheese and bread
- Where
- Greece
- Volunteers
- 12 people
- Sponsor
- Harokopio University
Oxidative Stress
Safety and Tolerability of Antioxidant (AT-001)for Reducing Brain Oxidative Stress
The purpose of this study is to determine the safety, bioavailability, and effectiveness of an organic yeast-selenium compound in reducing brain oxidative stress.
- Trial name
- NCT01731093
- Testing
- AT-001
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Alltech Life Sciences Inc.
Urolithiasis
Lime Powder Regimen (LPR) for Prevention of Renal Stone Recurrence
Lime powder regimen (LPR) is a lime-derived composition enriches with citrate/citric acid and potassium. LPR was invented to treat the renal stone patients with high risk of stone recurrence after stone removal.
- Trial name
- NCT03258190
- Testing
- Lime Powder Regimen
- Where
- Thailand
- Volunteers
- 137 people
- Sponsor
- Chulalongkorn University
Cellulite (Orange Peel Skin)
Safety and Efficacy of a Dietary Supplement in Females With Cellulite
To investigate the safety and efficacy of a dietary supplement on cellulite alleviation, fat deposits and quality of life.
- Trial name
- NCT01321268
- Testing
- dietary supplement for cellulite (PUFA, resveratrol, lycopene, beta carotene, lutein), Viatmin E
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Papilloma Viral Infection, Papillomavirus Infections
Efficacy of VIUSID® Plus GLIZIGEN® in Patients With Papilloma Virus Esophageal
A randomized, double-blind, phase II clinical trial was conducted versus placebo in 110 patients with esophageal human papillomavirus.
- Conditions
- Papilloma Viral Infection, Papillomavirus Infections, Esophageal Viral Wart, Esophageal Verrucous Carcinoma
- Trial name
- NCT03584308
- Testing
- Viusid®, Glizigen®
- Where
- Cuba
- Volunteers
- 110 people
- Sponsor
- Catalysis SL