Clinical trials: Antiphospholipid Syndrome
ANTIPHOSPHOLIPID SYNDROME
Hematopoietic Stem Cell Transplantation in Patients With Antiphospholipid Syndrome
Antiphospholipid syndrome is disease believed to be due to immune cells, cells which normally protect the body, but are now producing the protein which leads to abnormal clotting in the body.
- Trial name
- NCT00278616
- Testing
- Stem Cell Transplantation
- Where
- United States
- Sponsor
- Richard Burt, MD
Antiphospholipid Syndrome in Pregnancy
The Value of Placental Vascularization and Placental Volume in Pregnancy in APLS
Antiphospholipid antibodies are autoantibodies directed against phospholipid-binding proteins. Among these groups of antibodies, lupus anticoagulant (LA) and anticardiolipin antibodies (aCL)
- Trial name
- NCT03505840
- Testing
- Ultrasound with Doppler and 3D technology
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Antiphospholipid Syndrome (APS), Direct Oral Anticoagulants (DOACs)
OBServaToIre interNational Des Patients AnTiphospholipidEs traités Par Anticoagulants Oraux Directs
This registry will make it possible to collect large-scale data on SAPL patients, particularly those treated with DOACs, in order to better assess the frequency of thrombotic and hemorrhagic events in this population of…
- Conditions
- Antiphospholipid Syndrome (APS), Direct Oral Anticoagulants (DOACs), Thrombotic and Bleeding Events, Safety
- Trial name
- OBSTINATE 2 (NCT06929182)
- Testing
- "non-high risk" thrombotic APS patients treated with DOAC
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Antiphospholipid Antibody Syndrome in Pregnancy
Obstetric Antiphospholipid Antibody Syndrome : Contribution of the Evaluation of ADAMTS13 Made at the Diagnosis of Pregnancy on Evaluation the Risk of Pre-eclampsia
Study based on data concerning the first pregnancy treated and followed up after the diagnosis of oAPS in the NOH-APS cohort, according to clinical results already published; and on a thematic library collected and preserved at…
- Trial name
- NOH-ADAMTS (NCT04319341)
- Testing
- To study the prognostic value on the occurrence of pre-eclampsia, ADAMTS13 (ADAMTS13 protein and autoantibodies) in patients diagnosed with oAPS
- Where
- France
- Volunteers
- 513 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Antiphospholipid Syndrome, Endothelial Dysfunction
The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syndrome
Patients with hyperuricemia were confirmed to have higher risks of cardiovascular disease, but the exact mechanism remained to be elucidated.
- Conditions
- Antiphospholipid Syndrome, Endothelial Dysfunction, Hyperuricemia, Gout
- Trial name
- URIC (NCT01818505)
- Where
- Taiwan
- Volunteers
- 210 people
- Sponsor
- National Taiwan University Hospital
Systemic Lupus Erythematosus (SLE), Systemic Sclerosis
Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases
This study evaluates the safety and efficacy of YTS109 cells in adults with relapsed/refractory autoimmune diseases, such as Systemic Lupus Erythematosus (SLE), including LN and SLE-ITP, Sjogren's Syndrome, etc.
- Conditions
- Systemic Lupus Erythematosus (SLE), Systemic Sclerosis, Sjogren's Syndrome (SS), Inflammatory Myopathy
- Trial name
- NCT07236801
- Testing
- YTS109 cell
- Where
- 2 sites in China
- Volunteers
- 18 people
- Sponsor
- China Immunotech (Beijing) Biotechnology Co., Ltd.
Anti-Phospholipids Syndrome (APS), Systemic Lupus Erythematosus (SLE)
Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE)
The purpose of that register is to collect medical information about patients suffering of APS with or without associated SLE.
- Trial name
- SAPL-LUPUS (NCT02782039)
- Where
- 2 sites in France
- Volunteers
- 868 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Antiphospholipid Syndrome
Measurement of Anti-dsDNA by Both CLIFT & ELISA
detection of anti-ds DNA in patients with rheumatic diseases by two methodes : immunofluorescence \& ELISA
- Trial name
- NCT03303508
- Testing
- anti-ds DNA
- Volunteers
- 100 people
- Sponsor
- Assiut University
Primary Antiphospholipid Syndrome
The Safety and Efficiency of Sirolimus in Primary Antiphospholipid Syndrome: a Randomized Control Study
This study is an Investigator initiated, randomized, multicenter, double-blind, placebo-control study. The aim of this study is to evaluate the safety and efficiency of Sirolimus for primaty antiphospholipid syndrome patients at…
- Trial name
- NCT06504420
- Testing
- Sirolimus
- Volunteers
- 70 people
- Sponsor
- Peking University People's Hospital
Antiphospholipid Syndrome in Pregnancy
Dose Intralipid Infusion Reduces Pregnancy Complications Caused by Antiphospholipid Antibody Syndrome?
This study will address the value of adding intralipid infusion in reducing pregnancy complications related to antiphospholipid syndrome
- Trial name
- NCT04274803
- Testing
- Intralipid, 20% Intravenous Emulsion, Conventional therapy of antiphospholipis syndrome
- Where
- Egypt
- Sponsor
- Tanta University
Antiphospholipid Syndrome
Telitacicept Followed With Rituximab Therapy on APS Secondary to SLE
The aim of this study was to observe the clinical efficacy and safety of rituximab (RTX) combination with telitacicept (TA) in patients of systemic lupus erythematosus secondary antiphospholipid syndrome (APS).
- Trial name
- NCT05644210
- Testing
- Telitacicept, Rituximab, Aspirin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Qilu Hospital of Shandong University