Clinical trials: Antiplatelet Therapy
SCAD, ACS (Acute Coronary Syndrome)
Spontaneous Coronary Artery Dissection - AntipLatelet Therapy Intensity in Guided coNservative Management (SCAD-ALIGN) Trial
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome in which blood flow to the heart muscle is reduced or interrupted.
- Trial name
- SCAD-ALIGN (NCT07683923)
- Testing
- Acetylsalicylic acid ASA, ASA plus Clopidogrel
- Where
- 5 sites in Canada, Germany and 3 more
- Volunteers
- 3,518 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Coronary Artery Disease
Potential Impact of Cigarette Smoking on Platelet Reactivity in Patients on Dual Antiplatelet Therapy With P2Y12 Inhibitors
All consecutive patients undergone PTCA in the period between July 2013 and December 2013 are eligible to be enrolled. Study population are divided in : Group 1: smokers on dual antiplatelet therapy with ASA (100 mg once a day)…
- Trial name
- COPTER (NCT02026713)
- Testing
- quit smoking for a 2 weeks period
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Roma La Sapienza
Acute Coronary Syndrome
Can Very Low Dose Rivaroxaban in Addition to Dual Antiplatelet Therapy (DAPT) Improve Thrombotic Status in Acute Coronray Syndrome (ACS) ACS
A prospective, randomised, open label study of 3 clinically licensed treatments for ACS to assess the effects of these treatments on blood tests of endogenous fibrinolysis.
- Trial name
- VaLiDate-R (NCT03775746)
- Testing
- Clopidogrel 75Mg Tablet, Rivaroxaban 2.5Mg Tablet, Ticagrelor 90Mg Tablet
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- East and North Hertfordshire NHS Trust
Ischemic Stroke, TIA
Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events
Nondisabling cerebrovascular events represent the largest group of cerebrovascular disease with a high risk of recurrent stroke.
- Trial name
- ADANCE (NCT01924325)
- Testing
- Apixaban, Clopidogrel, Aspirin
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xijing Hospital
Coronary Artery Disease
The Study to Evaluate the Safety and Efficacy of the Onyx Family
Observation of the safety and efficacy of 1-month dual antiplatelet therapy (DAPT) after percutaneous coronary intervention using Onyx family stents in elderly patients aged 75 years or older
- Trial name
- NCT06577896
- Testing
- Onyx family
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Pusan National University Yangsan Hospital
Coronary Artery Disease
EDUCATE: The MEDTRONIC Endeavor Drug Eluting Stenting: Understanding Care, Antiplatelet Agents and Thrombotic Events
EDUCATE is a prospective, multi-center study designed to collect real-world safety and clinical outcomes in subjects receiving one or more Endeavor Zotarolimus-Eluting Stents and either clopidogrel and aspirin or prasugrel and…
- Trial name
- EDUCATE (NCT01069003)
- Testing
- Thienopyridine Therapy, Surveillance Arm
- Where
- United States
- Volunteers
- 2,272 people
- Sponsor
- Medtronic Vascular
Type2 Diabetes Mellitus, Coronary Heart Disease
Anti-thrombotic and Glucose Lowering Therapy in Diabetic Patients Undergoing PCI
Diabetes mellitus (DM) is one of the main risk factors for ischemic events in patients with coronary artery disease (CAD) and diabetes is a factor in several post-PCI (Percutaneous Coronary Intervention) risk scores.
- Trial name
- ARTHEMIS (NCT04481997)
- Testing
- Exposure to Anti-thrombotic treatment agents and glucose lowering therapy
- Where
- 12 sites in Portugal
- Volunteers
- 1,000 people
- Sponsor
- Associacao para Investigacao e Desenvolvimento da Faculdade de Medicina - CETERA
Acute Coronary Syndrome
Platelet Sub-study of the Neomindset Trial
The general purpose of the Neomindset trial is to evaluate the non-inferiority hypothesis for ischemic events and the superiority hypothesis for bleeding events resulting from platelet P2Y12 receptor inhibitors given as…
- Trial name
- NCT05767723
- Testing
- Dual antiplatelet therapy: Acetylsalicylic acid + ticagrelor OR Acetylsalicylic acid + prasugrel, Monotherapy: Ticagrelor alone OR Prasugrel alone
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Hospital Israelita Albert Einstein
Myocardial Infarction
STREAM-Strategic Reperfusion (With Tenecteplase and Antithrombotic Treatment) Early After Myocardial Infarction
This study aims at evaluating, in a proof of concept approach, the outcome of patients presenting with acute ST-elevation myocardial infarction within 3 hours of symptom onset in either a pre-hospital setting or community…
- Trial name
- NCT00623623
- Testing
- primary PCI, enoxaparin, catheterisation
- Where
- 201 sites in Austria, Belgium and 14 more
- Volunteers
- 1,899 people
- Sponsor
- Boehringer Ingelheim