Clinical trials: Anxiety, Generalized
Generalized Anxiety Disorder
Cognitive Behavioral Therapy (CBT) for Late Life Anxiety
The purpose of this research study is to assess the acceptability and feasibility of the implementation strategy and fidelity of cognitive-behavioral therapy (CBT) for older adults with Generalized Anxiety Disorder.
- Trial name
- NCT05380115
- Testing
- Cognitive Behavioral Therapy (CBT)
- Sponsor
- Wake Forest University Health Sciences
Pain, Nausea
Pediatric Integrative Medicine Trial Pilot
This study will investigate if adding complementary therapies such as acupuncture, massage and reiki to inpatient pediatric care is feasible and what the effects are on outcomes such as patient symptoms, cost, safety…
- Conditions
- Pain, Nausea, Vomiting, Anxiety
- Trial name
- PIM (NCT02028832)
- Testing
- PIM consult and service provision, Usual care
- Where
- Canada
- Volunteers
- 872 people
- Sponsor
- University of Alberta
Insomnia, Generalized Anxiety Disorder
Safety and Efficacy of Eszopiclone in Patients With Generalized Anxiety Disorder
To determine the safety and efficacy of eszopiclone as adjunctive therapy in the treatment of insomnia in patients with insomnia related to Generalized Anxiety Disorder.
- Trial name
- NCT00235508
- Testing
- Eszopiclone (Lunesta)
- Where
- 64 sites in United States
- Volunteers
- 420 people
- Sponsor
- Sumitomo Pharma America, Inc.
Uterine Fibroids (UF)
Ultrasound-Guided Stellate Ganglion Block Plus Propofol for Perimenopausal Insomnia With Anxiety
Laparoscopic myomectomy is a commonly performed minimally invasive gynecologic procedure. However, surgical trauma, tracheal intubation, and pneumoperitoneum may induce pronounced perioperative stress responses, resulting in…
- Trial name
- SGB-PROP-PIA (NCT07384468)
- Testing
- Ultrasound-Guided Stellate Ganglion Block
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Xiaochen Ji
Anxiety State
Preoperative Anxiety and BATHE Method
The patients were randomized into "Bathe" and "Control" groups by using the closed envelope technique. Demographic data and pre-examination anxiety scores State- Trait Anxiety Inventory (STAI) are recorded as entrance STAI for…
- Trial name
- NCT03468517
- Testing
- Bathe method:
- Where
- Turkey (Türkiye)
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Izmir Ataturk Training and Research Hospital
Generalized Anxiety Disorder
Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo & Active Control in Generalized Anxiety Disorder
The purpose of this study is to demonstrate that quetiapine SR (SEROQUEL®) is efficacious and safe in the acute treatment of patients with Generalized Anxiety Disorder.
- Trial name
- GOLD (NCT00329446)
- Testing
- Quetiapine Fumarate, Escitalopram oxylate
- Where
- 63 sites in United States
- Volunteers
- 800 people
- Sponsor
- AstraZeneca
Anxiety Generalized
Evaluation of Psychotherapeutic Intervention Model in Nursing
This study aims to evaluate the efficacy of a psychotherapeutic intervention model in nursing on the nursing diagnosis ineffective coping.
- Trial name
- NCT06076746
- Testing
- NIC Psychotherapeutic Intervention(s) for İneffective Coping, psychotherapeutic intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Tuğba Aşkan
Alcohol Dependence, Major Depression
Acamprosate in Alcoholics With Comorbid Anxiety or Depression
STUDY OBJECTIVES: The primary objective of this study is to compare the safety and efficacy of acamprosate versus placebo in the treatment of alcohol dependence in adults with co-occurring mood or anxiety disorders (specifically…
- Conditions
- Alcohol Dependence, Major Depression, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- NCT00330174
- Testing
- Acamprosate
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- Medical University of South Carolina
Anxiety Disorders
Study to Assess the Efficacy and Safety of Levetiracetam for the Treatment of Social Anxiety Disorder (Generalized Type)
Preclinical and clinical findings indicate that LEV has some anxiolytic potential. There is reason to believe that compounds with anxiolytic activity may have broad clinical utility across the anxiety spectrum.
- Trial name
- NCT00612859
- Testing
- levetiracetam
- Volunteers
- 217 people
- Sponsor
- UCB Pharma
Anxiety Generalized
Web-based Single-session Growth Mindset Intervention for Adolescent Anxiety
Anxiety disorders are the most common mental disorders worldwide. In Hong Kong, 7% of adolescents are diagnosed with anxiety disorders, and one in every four secondary school students reports clinical-level anxiety symptoms.
- Trial name
- NCT05027880
- Testing
- Web-based single-session growth mindset intervention for adolescent anxiety
- Where
- Hong Kong
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia
INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1
The focus of this study is not about what it is like to have a mental disorder, but instead the diagnostic experience. Some people find diagnoses helpful, but some find them upsetting and harmful.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia, Generalised Anxiety Disorder, Bipolar Disorder
- Trial name
- INCLUDE (NCT03131505)
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Generalized Anxiety Disorder
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of ITI-1284 as monotherapy treatment in patients meeting Diagnostic and Statistical Manual of Mental…
- Trial name
- NCT06701903
- Testing
- ITI-1284 10 mg, ITI-1284 20 mg
- Where
- 51 sites in United States, Bulgaria and 3 more
- Volunteers
- 570 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Fiberoptic Bronchoscopy
50% Nitrous Oxide and 50% Oxygen (MEOPA) Conscious Sedation Versus Placebo in Fiberoptic Bronchoscopy
Fiberoptic bronchoscopy may generate pain, anxiety or cough and dyspnea. It may then induce discomfort and then run down its yield.
- Trial name
- NCT00392522
- Testing
- 50% Nitrous Oxide and 50% Oxygen (MEOPA)
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Generalized Anxiety Disorder
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
This is a multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo as adjunctive therapy to GAD treatment in patients meeting Diagnostic…
- Trial name
- NCT06480383
- Testing
- ITI-1284 10 mg, ITI-1284 20 mg
- Where
- 56 sites in United States, Bulgaria and 3 more
- Volunteers
- 705 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Anxiety Disorders, Mood Disorders
Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders
Anxiety disorders are common, chronic, costly, debilitating to quality of life, and are more prevalent than any other class of disorders in every country in the world where surveys have been taken.
- Trial name
- NCT01243606
- Testing
- Single Diagnosis Treatment Protocol, Unified Protocol (UP)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston University Charles River Campus
Generalized Anxiety Disorder
A 5-Week Trial Of PD 0332334 And Alprazolam Extended Release Compared To Placebo In Patients With Generalized Anxiety Disorder
The purpose of this study is to evaluate the safety and efficacy of PD 0332334 compared to placebo in the treatment of Generalized Anxiety Disorder in an adult population
- Trial name
- NCT00921063
- Testing
- PD 0332334, Alprazolam extended release
- Volunteers
- 222 people
- Sponsor
- Pfizer
Generalized Anxiety Disorder
Self-selected or Predetermined Internet-based Treatment for Generalized Anxiety Disorder With Different Types of Support
This study evaluates two types of internet-based treatments for generalized anxiety disorder and two types of support. The treatments are a predetermined program for generalized anxiety disorder and a self-selected treatment.
- Trial name
- NCT03807193
- Testing
- Self-selected treatment, Predetermined treatment, Weekly support
- Where
- Sweden
- Volunteers
- 85 people
- Sponsor
- Linkoeping University
Generalized Anxiety Disorder, Social Anxiety Disorder
Cannabidiol for the Treatment of Anxiety Disorders: An 8-Week Pilot Study
This proposed study aims to evaluate the efficacy of daily Cannabidiol (CBD) Oil Capsules in treating symptoms of DSM-5 anxiety disorders, using a two-arm, 8-week randomized, placebo-controlled trial in adults aged 21-65 years.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03549819
- Testing
- Cannabidiol (CBD) Oil Capsules, Sunflower Lecithin Oil in Capsule
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Anxiety, Anxiety Disorders
Generalized Anxiety Disorder Adjunct Study
This study is being carried out to see if extended release quetiapine fumarate (Seroquel®XL) when added to standard selective serotonin reuptake inhibitor (SSRI) / serotonin-norepinephrine reuptake inhibitor (SNRI) therapy is…
- Conditions
- Anxiety, Anxiety Disorders, Anxiety Neuroses, Anxiety States
- Trial name
- NCT00534599
- Testing
- quetiapine fumarate XR
- Where
- 53 sites in United States
- Volunteers
- 409 people
- Sponsor
- AstraZeneca