Clinical trials: Anxiety, Generalized
Generalized Anxiety Disorder, Sleep Disturbances
Mechanisms of Sleep Disturbance in Children With Generalized Anxiety Disorder (GAD)
Anxiety disorders are among the most common mental disorders in children, affecting approximately 1 out of every 10 children and adolescents.
- Trial name
- NCT01032473
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Bronchoscopy, General Anesthesia
Preprocedural Video Education for Bronchoscopy Anxiety
The goal of this clinical trial is to learn whether preprocedural video education can reduce anxiety in adult patients who are scheduled to undergo bronchoscopy under general anesthesia.
- Trial name
- NCT07639437
- Testing
- Verbal + Audiovisual educational video, Verbal only
- Where
- Indonesia
- Volunteers
- 58 people
- Sponsor
- RSUP Persahabatan
Generalised Anxiety Disorder, Anxiety Disorders
CBT and the Neural Circuits of Anxiety
This study will aim to test whether specific neural circuitry changes, proposed on the basis of a neurocognitive model of anxiety, are a mechanism of action for Cognitive Behavioural Therapy (CBT) interventions.
- Conditions
- Generalised Anxiety Disorder, Anxiety Disorders, CBT, Anxiety Depression
- Trial name
- NCT05549102
- Testing
- Cognitive Behavioural Therapy, Waiting List
- Where
- United Kingdom
- Volunteers
- 174 people
- Sponsor
- UCLH/UCL Joint Research Office
Generalized Anxiety Disorder, Comorbid Opiate Dependence in Remission
Anxiety in Recovering Opiate Dependence
This is a 16 week study of the efficacy of quetiapine in treating symptoms of generalized anxiety disorder (GAD) in subjects with comorbid opiate dependence.
- Conditions
- Generalized Anxiety Disorder, Comorbid Opiate Dependence in Remission, Status Post Methadone-Maintenance Treatment
- Trial name
- NCT00668265
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Beth Israel Medical Center
Schizophrenia, Stress Disorders, Post-Traumatic
Optimizing Cognitive Remediation
Veterans with mental illness face challenges with community reintegration, including achieving vocational success, attaining their educational goals and going back to school, and maintaining a high quality of life.
- Conditions
- Schizophrenia, Stress Disorders, Post-Traumatic, Generalized Anxiety Disorder, Mood Disorders
- Trial name
- NCT04395157
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Anxiety, Decision Making
Impact of Anxiety on the Decision-making Processes of Anesthesiologists
Except for exaggerated situations in which aspiration risk seems obvious (or absent), the choice of a rapid sequence induction protocol for general anesthesia is often made under uncertainty, according to the individual…
- Conditions
- Anxiety, Decision Making, General Anesthesia
- Trial name
- DECIDINH (NCT05364801)
- Testing
- Survey
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Major Depressive Disorder, Depression
Cognitive Training for Mood and Anxiety Disorders
The purpose of this study is to investigate the effects of a computerized cognitive training program (an attention and memory exercise performed on a computer) on thinking and memory in individuals with mood and anxiety…
- Conditions
- Major Depressive Disorder, Depression, Bipolar Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT02256566
- Testing
- emotional memory training exercise, memory training exercise
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anxiety Disorders
An Eight-week Study Evaluating the Efficacy and Tolerability of Two Doses of SSR149415 in Outpatients With Generalized Anxiety Disorder
The objective is to evaluate the efficacy and safety of two doses of SSR149415 (250 mg and 100 mg twice daily) compared to placebo and paroxetine 20 mg once daily in outpatients with generalized anxiety disorder
- Trial name
- NCT00374166
- Testing
- SSR149415, Paroxetine
- Where
- United States
- Volunteers
- 325 people
- Sponsor
- Sanofi
Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder
CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
Anxiety-, obsessive-compulsive and trauma- and stressor-related disorders reflect a significant public health problem. This study is designed to evaluate the predictive power of a novel biomarker based on a CO2 challenge, thus…
- Conditions
- Obsessive-Compulsive Disorder, Post Traumatic Stress Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder
- Trial name
- NCT05467683
- Testing
- Exposure-Based Therapy
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Jasper A. Smits
Generalized Anxiety Disorder
Exploratory Study to Evaluate the Effect of SYN111 (Rufinamide) in Patients With Generalized Anxiety Disorder (GAD)
A Multi-Centered Randomized, Double-Blind, Placebo-Controlled, Phase 2, Exploratory Study to Evaluate the Effect of Rufinamide on Anxiety in Patients with Moderate to Severe Generalized Anxiety Disorder.
- Trial name
- NCT00595231
- Testing
- SYN111
- Where
- 2 sites in United States
- Volunteers
- 239 people
- Sponsor
- Biotie Therapies Inc.
Anxiety Disorders
Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety
Anxiety is the most common mental health problem in children and adolescents. This two-phased study will test the effects of an experimental computerized intervention aimed at reducing threat-based thinking (i.e., interpretation…
- Trial name
- NCT04245501
- Testing
- Cognitive Bias Modification for Interpretations (CBM-I), Interpretation Control Condition (ICC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Denver
Generalized Anxiety Disorder
A Trial of the Safety and Tolerability of SEP-363856 in Adults With Generalized Anxiety Disorder
This is a global, Phase 3, multicenter, open-label extension trial designed to evaluate the long-term safety, tolerability and efficacy of SEP-363856 administered at doses of 50 milligrams (mg) or 75 mg per day in adult…
- Trial name
- NCT07786454
- Testing
- SEP-363856
- Where
- 2 sites in United States
- Volunteers
- 1,120 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Generalized Anxiety Disease
A Phase 1 Study To Estimate The Effects Of PD 0332334 On Lithium Pharmacokinetics In Healthy Subjects
The purpose of this study is to investigate if PD 0332334 affects the pharmacokinetics of lithium by co-administering both drugs to healthy adults.
- Trial name
- NCT00820794
- Testing
- Lithium, PD 0332334
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Anxiety Disorders
Developing a Novel Digital Therapeutic for the Treatment of Generalized Anxiety Disorder
The investigators propose to develop and adapt Unwinding Anxiety phone app specifically for individuals with generalized anxiety disorder.
- Trial name
- NCT03683472
- Testing
- Unwinding Anxiety Phone App
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- MindSciences, Inc.
Anxiety Disorder
Combination of Paroxetine CR and Quetiapine for the Treatment of Refractory Generalized Anxiety Disorder
The purpose of this study is to examine the safety and efficacy of quetiapine for generalized anxiety disorder patients who remain symptomatic despite treatment with paroxetine CR.
- Trial name
- NCT00113295
- Testing
- Continued Paroxetine CR, Quetiapine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Generalized Anxiety Disorder
A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder
The purpose of this study is to evaluate the safety and efficacy of an investigational anti-anxiety medication relative to placebo in patients with generalized anxiety disorder (GAD)
- Trial name
- NCT00236054
- Testing
- Gabitril
- Where
- 19 sites in United States
- Volunteers
- 440 people
- Sponsor
- Cephalon
Anxiety; Generalized, Breast Diseases
Randomized, Placebo-Controlled Study: Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Patients
The study is designed to see if lavender aroma therapy reduces pre-operative anxiety in breast surgery patients.
- Conditions
- Anxiety; Generalized, Breast Diseases, Surgery
- Trial name
- NCT01837966
- Testing
- Lavender oil
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- NYU Langone Health
Chronic Pain, Generalized Anxiety Disorder
LIFU for Chronic Pain and Generalized Anxiety Disorder
A proof of concept case study to investigate accelerated LIFU protocol in chronic pain and anxiety populations.
- Trial name
- NCT07686354
- Testing
- Low Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Polytechnic Institute and State University
Stress Biomarkers, Anxiety
Evaluation of the Stress Levels of Children and Their Parents
The stress levels of the participating child and their parents were evaluated using saliva to measure the stress biomarkers.
- Trial name
- NCT06990919
- Testing
- Saliva collection
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Baskent University
Bipolar Disorder, Anxiety
Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)
The primary objective is to test the hypothesis that Quetiapine XR (Extended Release) monotherapy and adjunctive therapy is effective in the acute treatment of bipolar depression and comorbid generalized anxiety disorder in…
- Conditions
- Bipolar Disorder, Anxiety, Anxiety Disorders, Substance Use Disorders
- Trial name
- NCT00671853
- Testing
- Quetiapine XR
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University Hospitals Cleveland Medical Center